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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Adaptation Funding and Greenhouse Gas Emissions: Halo Effect or Complacency?
منشور في 2022"…Using a staggered difference-in-differences approach and an event study analysis, we find that receiving adaptation funding significantly and negatively affects several CO2 emissions measures, providing preliminary evidence of the presence of a halo effect of adaptation funding. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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Effectiveness of Positron Emission Tomography for Predicting Chemotherapy Response in Colorectal Cancer Liver Metastases
منشور في 2010"…The impetus for this research was finding viable cancer in patients with clearly negative findings on PET. We hypothesized that PET uptake levels were artificially decreased after chemotherapy. …"
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CO2 emissions integrated fuzzy model: A case of seven emerging economies
منشور في 2023"…Paper observes that (i) CO2 emissions from fossil fuels is the most significant factor distressing the carbon emission problem of E7 economies. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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CO<sub>2</sub> emissions integrated fuzzy model: A case of seven emerging economies
منشور في 2023"…Paper observes that (i) CO<sub>2</sub> emissions from fossil fuels is the most significant factor distressing the carbon emission problem of E7 economies. …"
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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Time series analysis of environmental quality in the state of Qatar
منشور في 2022"…The results indicate that electricity consumption, energy consumption, and the crop production index have a positive and significant relationship with GHGs, while economic growth has a negative and significant relationship in the long term with these gases. …"
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The Sustainability (Environmental and Economical) impact of upgrading Bahrain building regulations for affordable housing units: Case study in Bahrain
منشور في 2014"…The rapid increase of population and continues growth of cities in Bahrain leads to significant pressure on the ministry of housing to expand their housing development projects to serve the present and future population needs. …"
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Time series analysis of environmental quality in the state of Qatar
منشور في 2022"…The results indicate that electricity consumption, energy consumption, and the crop production index have a positive and significant relationship with GHGs, while economic growth has a negative and significant relationship in the long term with these gases. …"
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Does trade openness mitigate environmental degradation in Organisation for Economic Co‐operation and Development (OECD) countries? Implications for achieving sustainable developmen...
منشور في 2024"…Our findings suggest that as income levels rise, the indirect effect gradually outweighs the direct effect, leading to a significant reduction in long‐term CO<sub>2</sub> emissions in OECD countries.…"
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Effects of ethanol addition to diesel–biodiesel blends on the CI engine characteristics
منشور في 2024"…Thermal efficiency shows a reverse behaviour, with a small negative impact of ethanol addition. Biodiesel addition significantly increases carbon monoxide (CO) emissions, reaching an average of 190% across all speeds. …"
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Alterations in blood Lipoprotein & Apolipoprotein B profile induced by moderate acute & chronic alcohol intake in the rat model. (c2002)
منشور في 2002"…On the other hand, a 3% alcohol consumption (as beer or whisky) maintained for a two months period did not have an effect on fasting plasma TAG concentration while total and LDL cholesterol concentrations showed a significant decrease and HDL cholesterol concentration was moderately increased. …"
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masterThesis