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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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The Conceptualization, Perceptions, and Practice of Positive Education in University Student Accessibility Departments
منشور في 2023"…It is aiming to be the happiest country in the world; accordingly, the government and its educational entities are launching positive education and mental health initiatives, networks and workshops. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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Distribution network line protection in the presence of distributed generation
منشور في 2015"…When calculating the fault current levels in the network to choose the protection relay settings, it is important to correctly account for the fault contributions of inverter based DGs that represent a significant proportion of DGs connected to the distribution network. …"
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Modeling Human Resource Training Using Social Network Theory and Analytics
منشور في 2022"…Data were collected from 130 employees who have undergone training at their workplace in the past. Results from social network analysis and partial least squares path modelling show that the social network variables of betweenness, efficiency and tie strength positively impact training, while density and degree have no significant impact. …"
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masterThesis -
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Modelling the Impact of Bottlenecks on Arterial Travel Time Using Neural Networks
منشور في 2012احصل على النص الكامل
doctoralThesis -
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Securing Wireless Sensor Networks Against DoS attacks in Industrial 4.0
منشور في 2023"…Wireless Sensor Networks (WSNs) play a vital role in Industrial 4.0 by facilitating significant data collection for monitoring and control purposes. …"
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Willingness to pay for digital wellbeing features on social network sites: a study with Arab and European samples
منشور في 2024"…Multiple regression analyses revealed that SNUD and the need for cognition emerged as significant and positive predictors of WTP in both the European and Arab samples. …"
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Exploring social media adoption in small and medium enterprises in Iraq: pivotal role of social media network capability and customer involvement
منشور في 2022"…Notably, the positive effect of social media usage and SMEs’ performance was positively moderated by the capability of the social media networks and customer involvement. …"