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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Kefir's anti‑cancer potential was tested on CRC cell lines, Caco‑2 and HT‑29, through cytotoxicity, proliferation, and apoptotic assays. …"
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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Metallic coating thickness assessment over nonmagnetic metals using eddy current technology
منشور في 2019احصل على النص الكامل
doctoralThesis -
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Tensile Test Optimization Using the Design of Experiment and Soft Computing
منشور في 2023"…The results reveal that the area of the contact point exerts the most significant influence on the tensile test, followed by the operator and temperature. …"
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Photoactivatable RuII Complex Bearing 2,9‐Diphenyl‐1,10‐phenanthroline: Unusual Photochemistry and Significant Potency on Cisplatin‐Resistant Cell Lines
منشور في 2018"…Complex 1 demonstrated only marginal activity in the dark; its cytotoxicity increased significantly upon photoactivation with a high phototoxicity index (PI = [IC50 dark]/[IC50 light]) ranging from 39.2‐fold in A549 to over 100‐fold in MDA‐MB‐231. …"
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A Testing Framework for Blockchain-Based Energy Trade Microgrids Applications
منشور في 2024"…Before its deployment, an energy blockchain trading application needs to be tested in a virtual environment that is analogous to the real-world setting to ensure correct implementation and identify potential obstacles and opportunities. …"
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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Prescription Pattern of Antidepressants and the Potential for Personalized Medicine in the Qatari Population
منشور في 2021"…The number of patients, prescriptions, and diagnostic indications were analyzed. The chi-square test was used for identifying statistically significant association of the number of individuals prescribed with age category or gender. …"
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Willingness to participate in genome testing: a survey of public attitudes from Qatar
منشور في 2020"…Willingness to participate was significantly associated with basic literacy in genetics, a family history of genetic diseases, and previous experience with genetic testing through premarital screening. …"
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The effect of Dopamine Agonists on patients with advanced Parkinson's disease subjected to subthalamic deep brain stimulation. (c2000)
منشور في 2000"…Striatal dopamine concentration gets significantly reduced, and clinical symptoms, especially the motor handicap, prevail. …"
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masterThesis -
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Characterizing the Acoustic Behavior of Hexagonal Periodic Cellular Cores
منشور في 2020احصل على النص الكامل
doctoralThesis -
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Packed‐Bed Microreactor Under Taylor Flow for MOFs Catalyst Testing Demonstrated on Phenylacetylene Hydrogenation
منشور في 2024"…This study demonstrates the potential of the proposed catalyst testing system as a rapid and efficient approach for early‐stage exploration studies, particularly when limited quantities of catalyst, typically in the gram scale or less, are available.…"