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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Effect of corporate ethics and social responsibility on OCB: the role of employee identification and perceived CSR significance
منشور في 2021"…Partial least square structural equation modeling (PLS-SEM) is used to analyze the data and multi-group analysis is conducted to investigate the role of perceived CSR significance. …"
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Staff Development: A Study Into The Significance of Staff Professional Development Programs for Educators and Students Achievement
منشور في 2011"…Literature review conducted puts forth the rationale for such research work. In this context, various models of staff development have been discussed along with pros and cons. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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Numerical Evaluation of Shear Strength Enhancement in RC Beams Incorporating Various Web Opening Configurations and Pre-Stressed Fe-SMA Bar Sizes
منشور في 2024"…This study presents a numerical investigation to enhance the shear strength of RC beams with various web opening shapes by integrating pre-stressed Fe-SMA (Iron-based Shape Memory Alloy) bars. …"
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Shear Behavior of One-Way Reinforced Concrete Hollow Slabs Voided with PET Void Formers
منشور في 2023احصل على النص الكامل
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Modelling the utilization rates of pedestrian crosswalks
منشور في 2023"…The Multiple Linear Regression (MLR) model was also used to determine the utilization rate needed to develop the zebra crossing utilization model. …"
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Modelling the utilization rates of pedestrian crosswalks
منشور في 2023"…The Multiple Linear Regression (MLR) model was also used to determine the utilization rate needed to develop the zebra crossing utilization model. …"
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Ventilation System Modelling and Turbulence Minimisation
منشور في 2014"…Analytical procedures enabling the construction of simple, compact models including the relatively pointwise and significantly distributed system elements are proposed. …"
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The effectiveness of physical models in teaching anatomy
منشور في 2016"…The meta-analytical results are: educational methods using physical models yielded significantly better results when compared to all other educational methods for the overall knowledge outcome (p < 0.001) and for spatial knowledge acquisition (p < 0.001). …"
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The Impact of Implementing Maturity Models on IT Project Performance
منشور في 2021"…This research found that the implementation of maturity models have a significant relationship with the performance of IT projects, and plays an important role in influencing. …"
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