Metformin treatment inhibits motility and invasion of glioblastoma cancer cells حسب Al Hassan, Marwa

"…Furthermore, metformin’s efficiency in inhibiting 2D cell motility and cell invasion in addition to increasing cellular adhesion was also demonstrated in SF268 and U87 cells. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion حسب Khoury, Nathalie

"…Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.…"
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Aqueous urtica dioica leaves extract inhibits proliferation of acute myeloid leukemia cells in vitro حسب Rizk, Sandra

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Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy حسب Jia-Zhen Wu (6844793)

"…In both cell-free and cellular models of α-synuclein aggregation, after administration of DHM and Sal B, we observed significant inhibition of α-synuclein accumulation and aggregation. …"

The efficacy data of two household cleaning and disinfecting agents on Lens culinaris Medik and Vicia faba seed germination حسب Abou Elezz, Ahmed

"…A chemical analysis was performed using the ion chromatography (IC) to evaluate the effect of chloride and acetate anions uptake on the seedling germination in addition to other essential nutrients. A significant inhibition in seedling growth was observed with increasing the treatment concentration. …"
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Cucurbita pepo inhibits benign prostatic hyperplasia induced by testosterone in sprague-dawley rats. (c2011) حسب Nawfal, Tania M.

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Transglutaminase inhibition protects against oxidative stress-induced neuronal death downstream of pathological ERK activation حسب Sleiman, Sama F.

"…These small molecules inhibit increases in neuronal transamidating activity induced by oxidative stress; they also protect neurons downstream of pathological ERK activation when added well after the onset of the death stimulus. …"
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Targeted Inactivation of Rin3 Increases Trabecular Bone Mass by Reducing Bone Resorption and Favouring Bone Formation حسب Mahéva Vallet (18456729)

"…We conclude that Rin3 negatively regulates trabecular bone mass in mice by inhibiting osteoclastic bone resorption and favouring bone formation. …"

p53 Inhibition in Pancreatic Progenitors Enhances the Differentiation of Human Pluripotent Stem Cells into Pancreatic β-Cells حسب Idil I. Aigha (14913774)

"…NKX6.1 was overexpressed during MPCs specification. Inhibition of p53 using pifithrin-μ (PFT-μ) at the MPC stage resulted in a significant increase in the number of PDX1+/NKX6.1+ cells and a reduction in the number of CHGA+/NKX6.1− cells. …"

<i>Haematococcus pluvialis</i> Microalgae Extract Inhibits Proliferation, Invasion, and Induces Apoptosis in Breast Cancer Cells حسب Nouralhuda Alateyah (21363215)

"…TI significantly suppressed BC cell growth, inhibited migration and invasion and induced apoptosis. …"

A novel phosphorylated STAT3 inhibitor enhances T cell cytotoxicity against melanoma through inhibition of regulatory T cells حسب Abou-Ghazal, Mohamed K.

"…Similar effects were not observed in Treg-depleted CD3+CD25− T cell populations, confirming that the T cell activation by WP compounds is secondary to their inhibition of the Tregs. These results suggest that WP1066 enhances T cell cytotoxicity against melanoma through inhibition of Tregs.…"
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Resveratrol Inhibits Oxidative Stress and Prevents Mitochondrial Damage Induced by Zinc Oxide Nanoparticles in Zebrafish (<em>Danio rerio</em>) حسب Roberta Giordo (299595)

"…Mechanistically, we further showed that resveratrol inhibits ROS increase, prevents mitochondrial membrane potential dysfunction, and counteracts cell apoptosis/necrosis elicited by ZnO NP. …"

A novel inhibitor of STAT3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T cells حسب Abou-Ghazal, Mohamed K.

"…Although WP1066 did not induce immunological memory or enhance humoral responses to EGFRvIII, this compound reduced the production of immunosuppressive cytokines and chemokines (TGF-β, RANTES, MCP-1, VEGF), markedly inhibited natural and inducible Treg proliferation, and significantly increased cytotoxic immune responses of T cells. …"
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The efficacy data of two household cleaning and disinfecting agents on Lens culinaris Medik and Vicia faba seed germination حسب Ahmed Abou Elezz (16931832)

"…A chemical analysis was performed using the ion chromatography (IC) to evaluate the effect of chloride and acetate anions uptake on the seedling germination in addition to other essential nutrients. A significant inhibition in seedling growth was observed with increasing the treatment concentration. …"

L1-CAM knock-down radiosensitizes neuroblastoma IMR-32 cells by simultaneously decreasing MycN, but increasing PTEN protein expression حسب Rached, Johnny

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Curcumin Induces Apoptotic Cell Death via Inhibition of PI3-Kinase/AKT Pathway in B-Precursor Acute Lymphoblastic Leukemia حسب Shilpa Kuttikrishnan (3520079)

Morphological changes in amblyopic eyes in choriocapillaris and Sattler’s layer in comparison to healthy eyes, and in retinal nerve fiber layer in comparison to fellow eyes through... حسب Masri, Oussama Samer

"…Results The method of measuring reflectivity is good to excellent reliability for all regions of interest except the fourth. The mean reflectivity of the choriocapillaris and Sattler’s layer in amblyopic eyes were significantly lower than in healthy eyes (p = 0.003 and p = 0.008 respectively). …"
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Selective induction of apoptosis in T-cell acute lymphoblastic leukemia by pristimerin through dual PI3K/AKT pathway inhibition and ROS generation حسب Shilpa Kuttikrishnan (3520079)

"…Prist significantly increases reactive oxygen species (ROS) levels and depletes glutathione (GSH), leading to mitochondrial dysfunction and cytochrome c release. …"

Antitumor activity of β-2-himachalen-6-ol in colon cancer is mediated through its inhibition of the PI3K and MAPK pathways حسب Daaboul, Hamid E.

"…Western blot analysis revealed a significant decrease in p-Erk, p-Akt, pro-caspase-3 and Bcl-2 and an increase in p53, p21, Bax and PARP proteins. …"
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A novel inhibitor of signal transducers and activators of transcription 3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T ce... حسب Abou-Ghazal, Mohamed

"…Although WP1066 did not induce immunologic memory or enhance humoral responses to EGFRvIII, this compound reduced the production of immunosuppressive cytokines and chemokines (transforming growth factor-β, RANTES, MCP-1, vascular endothelial growth factor), markedly inhibited natural and inducible Treg proliferation, and significantly increased cytotoxic immune responses of T cells. …"
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