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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Does standalone phacoemulsification lower intraocular pressure in glaucomatous eyes? A systematic review and meta-analysis
منشور في 2025"…In conclusion, standalone phacoemulsification significantly lowers IOP and reduces the need for glaucoma medications in patients with glaucoma.…"
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Nomograph derivation for underwater sour gas releases in shallow waters based on computational fluid dynamics simulations
منشور في 2024"…<p dir="ltr">Ruptured <u>underwater pipelines</u> releasing sour gas (i.e., natural gas with high concentrations of H<sub>2</sub>S) pose significant threats to environmental safety due to their toxic and contaminative properties. …"
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Release of colloids in saturated porous media under transient hydro-chemical conditions: A pore-scale study
منشور في 2021"…<p dir="ltr">The deposition and consequent release of colloids pose a significant challenge to the environment, groundwater quality and human health. …"
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Renewable Energy, Coal as a Baseload Power Source, and Greenhouse Gas Emissions: Evidence from U.S. State-Level Data
منشور في 2017"…After controlling for other sources of emissions, U.S. states that produce a larger share of renewable energy are found to have lower GHG emissions. It is estimated that a 10% increase in the share of renewable energy could decrease CH4 emissions by about 0.26%. …"
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Cellulose-based materials for antimicrobial water treatment: functionalization strategies and applications
منشور في 2025"…Water contamination by pathogenic microorganisms poses a significant threat to public health and ecosystems, necessitating the development of sustainable and efficient water decontamination technologies. …"
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Antibacterial Activities of Selected Pure Compounds Isolated from Gut Bacteria of Animals Living in Polluted Environments
منشور في 2020"…Using purified compounds, assays were performed to determine their antibacterial properties using serial dilution method, cytotoxic effects using lactate dehydrogenase release, and cell viability using MTT assay. The results revealed that the purified compounds exhibited significant antibacterial activities (p < 0.05) against selected Gram-negative (Pseudomonas aeruginosa) and Gram-positive bacteria (Streptococcus pyogenes) with effective MIC₅₀ and MIC₉₀ at μg concentrations, and with minimal effects on human cells as observed from LDH and MTT assays. …"
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Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma
منشور في 2020"…Finally, only in lower sumac dose, significant decreases in methylation status of three out of five gene promoters–ATM, PTEN, and TIMP3 (PITX2 and RASSF1 promoters were not changed). …"
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Gut bacteria of Cuora amboinensis (turtle) produce broad-spectrum antibacterial molecules
منشور في 2019"…Antimicrobial resistance is a major threat to human health, hence there is an urgent need to discover antibacterial molecule(s). …"
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Symptoms of depression and anxiety in anorexia nervosa
منشور في 2014"…For those with AN, psychological, nutritional and biological parameters improved significantly during hospitalisation. Levels of serotonin markers were significantly lower in the AN group compared to the control group, at admission and at discharge. …"
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Renal Function Decline in Recipients and Donors of Kidney Grafts
منشور في 2015"…In living donors, renal function decline after the first year corresponded to 0.7 ml/min/1.73 m2, was significantly lower than that of recipients (p < 0.001), and was determined by donor age at nephrectomy. …"
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Morphological changes in amblyopic eyes in choriocapillaris and Sattler’s layer in comparison to healthy eyes, and in retinal nerve fiber layer in comparison to fellow eyes through...
منشور في 2021"…The mean reflectivity of the choriocapillaris and Sattler’s layer in amblyopic eyes were significantly lower than in healthy eyes (p = 0.003 and p = 0.008 respectively). …"
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The Protective Effects of Daucus carota L. ssp. carota and Cannabis sativa L. Extracts against Cisplatin Induced Nephrotoxicity in Animal Models
منشور في 2021"…In addition, COE treatment caused a significant decrease in urinary albumin excretion. Furthermore, Western blot analysis with the antibodies against COX-2 was significantly lower in cisplatin-intoxicated mice with COE in comparison to mice treated with cisplatin alone. …"
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Modification of glucocorticoid effects on body weight gain, plasma lipids by changes in diet composition
منشور في 2003"…Prednisolone-treated groups revealed significantly lower intestinal absorption. However, prednisolone-treated high-carbohydrate (HC) fed rats showed significantly higher weight gain, concomitant with a significant increase in feed efficiency. …"
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Structure-activity relationships of copper-based metal-organic Frameworks: Investigating antibacterial mechanisms against gram-positive and gram-negative bacteria
منشور في 2025"…<p dir="ltr">Bacterial infection poses a significant concern and represents a global threat. …"