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يعرض 1 - 20 نتائج من 541 نتيجة بحث عن '(( significantly negative roles ) OR ( significant increase decrease ))', وقت الاستعلام: 0.10s تنقيح النتائج
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    The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... حسب Wesal Habbab (17346961)

    منشور في 2019
    "…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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    A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

    منشور في 2024
    "…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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    Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex حسب Wesam S. Ahmed (10170053)

    منشور في 2022
    "…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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    The significance of general skills training for early career graduates: relationships with perceived organizational support, job satisfaction and turnover intention حسب Pinnington, Ashly

    منشور في 2023
    "…Findings– The main finding is that participation in general skills training (PGST) does not directly impact turnover intention, rather POS is a mechanism through which this negative relationship operates. This study also found significant evidence for serial mediation by POS on PGST and its relationship with turnover intention. …"
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    Phospholipase C negatively regulates Rac/Cdc42 activation in antigen-stimulated mast cells حسب El-Sibai, Mirvat

    منشور في 2007
    "…The Rho GTPases Rac and Cdc42 play a central role in the regulation of secretory and cytoskeletal responses in antigen-stimulated mast cells. …"
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    article
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    Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion حسب Khoury, Nathalie

    منشور في 2014
    "…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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    article
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    Transcriptional alterations of protein coding and noncoding RNAs in triple negative breast cancer in response to DNA methyltransferases inhibition حسب Ramesh Elango (7542068)

    منشور في 2021
    "…A number of studies have associated alterations in DNMT activity to tumorigenesis; however, the exact role of DNMTs in shaping the genome in triple negative breast cancer (TNBC) is still being unraveled.…"
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    Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells حسب Shebaby, Wassim N.

    منشور في 2014
    "…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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    article
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    The Role of Media Literacy in Countering Misinformation حسب Hamzeh, Dana

    منشور في 2023
    "…It highlights the importance of implementing digital media literacy within the educational system to enable the young generation to fight the negative consequences of social media. Results indicate a significant positive association between youth media exposure and them believing in COVID-19 conspiracy theories. …"
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    masterThesis
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    Assessing uncertainty in image-based monitoring: addressing false positives, false negatives, and base rate bias in structural health evaluation حسب Vagelis Plevris (14158863)

    منشور في 2025
    "…The Base Rate Bias plays a significant role, as low probabilities of actual damage often lead to misinterpretation of positive results. …"
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    Challenging others when posting misinformation: a UK vs. Arab cross-cultural comparison on the perception of negative consequences and injunctive norms حسب Muaadh Noman (17760902)

    منشور في 2024
    "…Moreover, UK participants’ reporting of how others perceive negative impact on the person being challenged and injunctive norms were significant predictors, while for the Arabs, only the perceived relationship costs emerged as a significant predictor. …"
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    Structure-activity relationships of copper-based metal-organic Frameworks: Investigating antibacterial mechanisms against gram-positive and gram-negative bacteria حسب Muhammad Hubab (20639153)

    منشور في 2025
    "…<u>Transmission Electron Microscopy</u> (TEM) analysis verified the significant <u>biocidal</u> activity of Cu-MOFs against both the Gram-negative (<i><u>Escherichia coli</u></i>) and Gram-positive (<u>Staphylococcus aureus</u> and <i>Bacillus subtilis</i>) bacteria, by disrupting their cell membranes and inducing cell death primarily through Cu<sup>2+</sup> <u>ion release</u>. …"
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    Structure-Activity Relationships of Copper-Based Metal-Organic Frameworks: Investigating Antibacterial Mechanisms against Gram-Positive and Gram-Negative Bacteria حسب Muhammad Hubab (20639153)

    منشور في 2025
    "…Transmission Electron Microscopy (TEM) analysis verified the significant biocidal activity of Cu-MOFs against both the Gram-negative (Escherichia coli) and Gram-positive (Staphylococcus aureus and Bacillus subtilis) bacteria, by disrupting their cell membranes and inducing cell death primarily through Cu<sup>2</sup><sup>+</sup> ion release. …"
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    The Role of Leaders in Reducing Role Ambiguity to Enhance Employee Motivation and Commitment: A Study Among School leaders and Staff in Al Ain Schools حسب ALDHAERI, ALYAZYA

    منشور في 2024
    "…With rapid organizational change in UAE schools under the educational reforms and aspirations to participate in the knowledge economy, this study seeks to examine the role of leaders in Al Ain public schools in mitigating the negative impact of role ambiguity on employee dedication and motivation. …"
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    The role of institutional quality in reducing environmental degradation in Canada حسب Shahriyar Mukhtarov (19325662)

    منشور في 2024
    "…Estimation findings showed that institutional quality, renewable energy use, and total factor productivity exert a statistically significant and negative influence on CO<sub>2</sub> emissions. …"