Recombinant prostate-specific antigen proaerolysin shows selective protease sensitivity and cell cytotoxicity حسب Abi-Habib, Ralph

"…Recombinant modified proaerolysin had no furin sensitivity and markedly increased prostate-specific antigen sensitivity relative to wild-type proaerolysin. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Cardiac phosphodiesterases are differentially increased in diabetic cardiomyopathy حسب Hanna, Rita

"…However, DCM was not associated with changes in PDE4A gene expression irrespective of the disease stage. Significance We show for the first time differential and time-specific regulations in cardiac PDEs, data that may prove useful in proposing new therapeutic approaches in T1D-induced DCM.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Board changes and CEO turnover حسب Dah, Mustafa A.

"…For firms that decrease independence, the CEO turnover performance sensitivity significantly decreases following SOX. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"

Effect of increasing the number of anchors on the flexural performance of FRP-strengthened RC beams حسب Hawileh, Rami A.

"…The first beam was strengthened and unanchored, and the other two beams were strengthened and anchored with one or two 14-mm diameter FRP anchors on each side, respectively. Results showed that increasing the number of anchors significantly improved the flexural behavior of the strengthened beam in terms of the beam's response at failure and the strain utilized in the FRP laminates. …"
احصل على النص الكامل

Performance and microbial community variations of anaerobic digesters under increasing tetracycline concentrations حسب Xiong, Yanghui

"…An increase in the abundance of tetracycline resistance genes associated with ribosomal protection proteins was observed after 30 days of exposure to high concentrations of tetracycline, while other targeted resistance genes showed no significant changes. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Increased Levels of Circulating and Tumor-Infiltrating Granulocytic Myeloid Cells in Colorectal Cancer Patients حسب Salman M. Toor (8854751)

"…<p dir="ltr">Increased levels of myeloid cells, especially myeloid-derived suppressor cells (MDSCs), have been reported to correlate with bad prognosis and reduced survival in cancer patients. …"

Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

"…Global gene expression profiling of LY411575-treated cells revealed changes in multiple signaling pathways, including focal adhesion, insulin, TGFβ, IL6, and Notch signaling, and decreased the expression of genes associated with functional categories of tissue development. …"

Vocal Changes in Patients With Polycystic Ovary Syndrome حسب Hannoun, Antoine

"…There was no statistically significant difference in the acoustic parameters except for an increase in the relative average perturbation (P value = 0.035) and a decrease in maximum phonation time (P value = 0.001) in patients with PCOS. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion حسب Khoury, Nathalie

"…Western blotting results revealed an upregulation in Bax:Bcl‑2 ratio, confirming the pro‑apoptotic effect of kefir, and an increase in p53 independent‑p21 expression upon kefir treatment. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Increasing methylation of sperm rDNA and other repetitive elements in the aging male mammalian germline حسب Ramya Potabattula (4401160)

"…Here, we used bisulfite pyrosequencing and show that methylation of the rDNA transcription unit including upstream control element (UCE), core promoter, 18S rDNA, and 28S rDNA in human sperm also significantly increases with donor's age. …"

The Association of Hypertension with Increased Mortality Rate During the COVID-19 Pandemic: An Update with Meta-analysis حسب Ahmad R. Al-Qudimat (17337808)

"…Meta-regression analysis results also showed a statistically significant association between hypertension and COVID-19 mortality.…"

Targeted Inactivation of Rin3 Increases Trabecular Bone Mass by Reducing Bone Resorption and Favouring Bone Formation حسب Mahéva Vallet (18456729)

"…Bone histomorphometry showed a lower osteoclast surface / bone surface (Oc.S/BS%) at 8 weeks in Rin3⁻/⁻ mice compared to wild type (24.1 ± 4.7 vs. 29.7 ± 6.6; p = 0.025) but there were no significant differences in markers of bone formation at this time. …"

Triple helix components supporting STEM education to increase future STEM careers in the United Arab Emirates حسب Husain, Fatima Yousif

"…Increasing communication between government schools, universities, and industry can benefit STEM education programs and STEM careers. …"
احصل على النص الكامل

Increased levels of CSF total but not oligomeric or phosphorylated forms of alpha-synuclein in patients diagnosed with probable Alzheimer’s disease حسب Nour K. Majbour (8809316)

"…CSF total α-syn (t-α-syn) significantly increased in the AD group (p < 0.0001) compared to controls, while oligomeric- and phosphorylated-Ser129-α-syn did not change significantly. …"

Effective Approach for Increasing the Heteroatom Doping Levels of Porous Carbons for Superior CO2 Capture and Separation Performance حسب Abdelmoaty, Yomna H

احصل على النص الكامل

Essays on the effect of excess compensation and governance changes on firm value حسب Dah, Mustafa A.

"…Our results suggest that an increase in director excess compensation decreases the likelihood of CEO turnover, reduces the turnover-performance sensitivity, and increases managerial entrenchment. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Increased MicroRNA Levels in Women With Polycystic Ovarian Syndrome but Without Insulin Resistance: A Pilot Prospective Study حسب Alexandra E. Butler (6189536)

Auto-immunoproteomics analysis of COVID-19 ICU patients revealed increased levels of autoantibodies related to the male reproductive system حسب Frank Schmidt (207186)

Perceptions of Science Teachers Regarding Instruction that Increase High School Students' Motivation to Learn Science in Al Ain City حسب ALKHATIB, SARA

"…For the demographic variables, the gender of the teacher affects their attitude and skill in favor of male teachers. The results showed that there were statistically significant differences due to the age of the instructor, and these differences were in favor of teachers who were thirty years old and older. …"
احصل على النص الكامل