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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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Drivers obesity and road crash risks in the United States
منشور في 2015"…<p dir="ltr">We assessed obesity trends in US drivers involved in fatal crashes since 1999 and distinguished whether crash risk factors were different between obese and non-obese drivers. …"
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GIS-based spatiotemporal analysis for road traffic crashes; in support of sustainable transportation Planning
منشور في 2023"…Road traffic crashes pose a significant challenge worldwide, necessitating increased efforts to reduce them and promote sustainable transport systems. …"
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احصل على النص الكامل
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GIS-based spatiotemporal analysis for road traffic crashes; in support of sustainable transportation Planning
منشور في 2023"…<p>Road traffic crashes pose a significant challenge worldwide, necessitating increased efforts to reduce them and promote sustainable transport systems. …"
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The development of psychological and associated mental health disorders after road traffic crashes and other injuries
منشور في 2015"…<p dir="ltr">Injury contributes approximately 12% of the world’s burden of injury and there is increasing evidence that injury results in the new onset of a range of psychiatric disorders. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …"
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Suppression of Unstable Flow by Using Rough Surfaces at Small Mass Flow Rates in a Radial Diffuser
منشور في 2006احصل على النص الكامل
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Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance
منشور في 2025"…Therefore, coaches should consider longer continuous bouts when planning SSGs‐based training to significantly decrease TMD and enhance technical‐tactical performance in soccer SSGs.…"
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YOLO-DefXpert: An Advanced Defect Detection on PCB Surfaces Using Improved YOLOv11 Algorithm
منشور في 2025"…Accurately identifying small defects on PCB surfaces remains a considerable challenge, particularly under complex background conditions, due to the intricate and compact layout of the boards. …"
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Optical pavement treatments and their impact on speed and lateral position at transition zones: A driving simulator study
منشور في 2021"…Previous studies have highlighted that crash rates are usually higher in these sections. …"
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An Analysis of Thermal Comfort at the School Outdoor Spaces: A Case Study of the American School of Creative Science, Dubai, UAE
منشور في 2022"…Additionally, the addition of vegetation alone had an impact on the microclimate decreasing it by 5%. Thus, combining the strategies of vegetation, shade, green facades/roofs and small water features resulted in 5% to 25% reduction in PET depending on the corresponding location being analyzed. …"
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Past, present and future global mangrove primary productivity
منشور في 2024"…However, significant regional changes were identified, including substantial increases in NPP in the Southwest Australian Shelf (60.58 ± 97.9 %), the Warm Temperate Northeast Pacific (43.75 ± 65.7 %), and the Warm Temperate Northwest Pacific (31.55 ± 55.7 %), as well as decreases in <u>Southeast Asian </u>provinces like the Java Transitional (11.45 ± 6.2 %) and Western Coral Triangle (7.61 ± 9.6 %). …"