يعرض 1 - 20 نتائج من 1,366 نتيجة بحث عن '(( significantly target based ) OR ( significant ((nn decrease) OR (we decrease)) ))', وقت الاستعلام: 0.12s تنقيح النتائج
  1. 1

    Exploring the Significance of Publication-Age-Based Parameters for Evaluating Researcher Impact حسب Ghulam Mustafa (458105)

    منشور في 2023
    "…</p><h2>Other Information</h2><p dir="ltr">Published in: IEEE Access<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1109/access.2023.3304013" target="_blank">https://dx.doi.org/10.1109/access.2023.3304013</a></p>…"
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    Treating Cancers Using Nature’s Medicine: Significance and Challenges حسب Samson Samuel (6828956)

    منشور في 2021
    "…In recent decades, the emphasis on identifying therapeutic plant-based active principles led to significant advancements in the identification and use of natural compounds to treat various diseases (Figure 1) [2,3]. …"
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    Detection of statistically significant network changes in complex biological networks حسب Raghvendra Mall (581171)

    منشور في 2017
    "…</p><h3>Methods</h3><p dir="ltr">In this paper, we propose an improvement over the state-of-the-art based on the Generalized Hamming Distance adopted for evaluating the topological difference between two networks and estimating its statistical significance. …"
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    Significance of Avicennia Marina in the Arabian Gulf Environment: A Review حسب Kaiprath Puthiyapurayil Haseeba (21392966)

    منشور في 2025
    "…This review addresses the current knowledge gap by providing an overview of Avicennia marina distribution in the Gulf, exploring the significance of its ecosystem services, analyzing the impacts of stressors, and examining conservation and restoration efforts, with attention to nature-based and biotechnological approaches for promoting mangrove growth and conservation in the Gulf.…"
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    Targeting acute myeloid leukemia cells with novel photosensitive ruthenium-based metal-organic compounds. (c2015) حسب Azar, Daniel Fadi

    منشور في 2016
    "…In this study, we aim to establish a ruthenium-based model for effectively targeting AML, with the goal of later developing approaches to selectively target AML with complexes based on this model. …"
    احصل على النص الكامل
    احصل على النص الكامل
    masterThesis
  8. 8

    Nanoparticle enrichment mass-spectrometry proteomics identifies protein-altering variants for precise pQTL mapping حسب Karsten Suhre (67967)

    منشور في 2024
    "…</i>) where we quantify over 18,000 unique peptides from nearly 3000 proteins in more than 320 blood samples from a multi-ethnic cohort in a bottom-up, peptide-centric, mass spectrometry-based proteomics approach. We identify 184 protein-altering variants in 137 genes that are significantly associated with their corresponding variant peptides, confirming target specificity of co-associated affinity binders, identifying putatively causal cis-encoded proteins and providing experimental evidence for their presence in blood, including proteins that may be inaccessible to affinity-based proteomics.…"
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    A Novel Steganography Technique for Digital Images Using the Least Significant Bit Substitution Method حسب Shahid Rahman (16904613)

    منشور في 2022
    "…Therefore, the proposed work, in this paper, is based on the Least Significant Bit (LSB) substitution method. …"
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    A New Restriction Endonuclease-Based Method for Highly-Specific Detection of DNA Targets from Methicillin-Resistant Staphylococcus aureus حسب Maria W. Smith (18807382)

    منشور في 2014
    "…We developed a new approach for analysis of PCR amplicons based on restriction endonuclease digestion. The first stage of the restriction enzyme assay is hybridization of a target DNA to immobilized complementary oligonucleotide probes that carry a molecular marker, horseradish peroxidase (HRP). …"
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    A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

    منشور في 2024
    "…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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    Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex حسب Wesam S. Ahmed (10170053)

    منشور في 2022
    "…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …"
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    Deep random vector functional link transformer network with multiple output layers for significant wave height forecasting حسب Aryan Bhambu (18767731)

    منشور في 2025
    "…This paper introduces a novel random vector functional link transformer (RFT) and ensemble deep random vector functional link transformer (edRFT) networks to capture the dynamic characteristics of significant wave heights. The model employs hidden blocks based on transformer encoders to effectively capture complex sequential dependencies in the data. …"
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    Protecting Private Attributes in App Based Mobile User Profiling حسب Imdad Ullah (18372291)

    منشور في 2020
    "…<p dir="ltr">The Analytics companies enable successful targeted advertising via user profiles, derived from the mobile apps installed by specific users, and hence have become an integral part of the mobile advertising industry. …"
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    Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

    منشور في 2019
    "…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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    Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications حسب Sumama Nuthana Kalva (17302906)

    منشور في 2025
    "…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …"
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