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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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LCMV-Based EEG & FNIRS-Based Brain Source Localization of Mental Stress
منشور في 2024احصل على النص الكامل
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Face-To-Face, Blended, Hybrid, and Online Instructional Delivery Methods: a Comparative Study of English Language Learners’ Grades in a Mathematics Course in a Higher Education Ins...
منشور في 2020"…Assumptions of analysis of variance (ANOVA) were examined. The ANOVA revealed that there was a significant difference in students’ average grades between the different instructional delivery methods. …"
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β-2-himachalen-6-ol protects against skin cancer development in vitro and in vivo
منشور في 2017"…A significant decrease in protein levels of p53 and Bcl-2 and a significant increase in p21 and Bax were observed. …"
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Temporomandibular joint osseous characteristics in skeletal short and long facial types with and without temporomandibular disorders: A three-dimensional comparative study
منشور في 2025"…Short facial patients showed significant variance in condyle length and width, while long facial patients demonstrated major differences in condyle height. …"
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Teachers and students interacting around the textbook
منشور في 2001"…Significant differences were found in teacher questions, student communication, and teacher feedback. …"
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The relationship between Determinants of Risk Governance assurance and efficacy of the Public projects in the Government of Dubai from the perspective of Internal Audit Function
منشور في 2018"…By collecting the opinions of managers and executives working in the risk management sector, these factors were appraised and classified. Furthermore, different variables were analysed to find that some of them may be more significant than others. …"
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Renewable Energy, Coal as a Baseload Power Source, and Greenhouse Gas Emissions: Evidence from U.S. State-Level Data
منشور في 2017"…It is estimated that a 10% increase in the share of renewable energy could decrease CH4 emissions by about 0.26%. …"
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article