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Detection of statistically significant network changes in complex biological networks
منشور في 2017"…</p><h3>Methods</h3><p dir="ltr">In this paper, we propose an improvement over the state-of-the-art based on the Generalized Hamming Distance adopted for evaluating the topological difference between two networks and estimating its statistical significance. …"
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Why does the adverse effect of inappropriate MRI for LBP vary by geographic location? An exploratory analysis
منشور في 2019"…The aim was to explore whether the known risk of increased length of disability (LOD) associated with eMRI scanning not adherent to guidelines for occupational LBP varies according to patient and area-level characteristics, and the potential reasons for any observed variations.…"
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Proteomic Characterization Of Clinical Candida glabrata Isolates With Varying Degrees Of Virulence And Resistance To Fluconazole
منشور في 2024"…Candida glabrata, an opportunistic fungal pathogen, is a significant contributor to mortality among individuals with weakened immune systems. …"
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Performance and microbial community variations of anaerobic digesters under increasing tetracycline concentrations
منشور في 2017"…Results revealed that for all of the tested tetracycline concentrations, no major sustained impact on methane production was observed. Instead, a significant increase in propionic acid was observed in the reactor subjected to the highest concentration of tetracycline (20 mg/L). …"
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How does varying the number of personas affect user perceptions and behavior? Challenging the ‘small personas’ hypothesis!
منشور في 2022"…Our study results from eye-tracking and survey data suggest that when using interactive persona systems, the number of personas can be increased from the conventionally suggested ‘less than ten’, without significant negative effects on user perceptions or task performance, and with the positive effects of increasing engagement with the personas, having a more diverse representation of the end-user population, as well as users accessing personas from more varied demographic groups for a design task. …"
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Stemming cardiovascular diseases in Qatar
منشور في 2015"…The importance of diabetes as a risk factor, however, was found to be higher than other countries in the Gulf region and significantly higher than the US.</p><p>“Public health officials should design programmes to improve the prevention, diagnosis, and management of risk factors such as diabetes and hypertension,” says Christos, as well as work on effective awareness campaigns to create a culture of preventive health in Qatar.…"
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Olodaterol for the treatment of chronic obstructive pulmonary disease
منشور في 2016"…In 48- and 6-week Phase III clinical trials of olodaterol evaluating various lung function and symptomatic outcomes in patients with moderate to very severe COPD, olodaterol use was associated with significant improvements in spirometry outcomes, such as postbronchodilator forced expiratory volume in one second (FEV1), as well as dyspnea severity and quality-of-life measures. …"
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The efficacy of colchicine in the management of coronavirus disease 2019
منشور في 2020"…If colchicine proved to be effective, it would be a significant milestone in the management of COVID-19, a disease with limited available therapeutic options.…"
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Breast Disease-Related Educational Outcomes at the University of Florida
منشور في 2000"…Limiting breast surgery to a single service does not appear to improve resident accumulation and retention of breast disease-related knowledge. …"
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The effect of self-reported flossing behavior on cardiovascular disease events and mortality Findings from the 2009-2016 National Health and Nutrition Examination Surveys
منشور في 2025"…Participants in the not flossing group had significantly elevated CRP levels, even after multivariable adjustments. …"
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COVID‐19 effect on patients with noncommunicable diseases: A narrative review
منشور في 2022"…Physical distancing and lockdown made significant obstacles to populations, particularly healthcare systems. …"
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Combined bronchodilators (tiotropium plus olodaterol) for patients with chronic obstructive pulmonary disease
منشور في 2015"…Several well-designed randomized trials confirmed that the synergistic effect of both drugs in combination was able to improve lung function and health-related quality of life without a significant increase in adverse effects. …"
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Systematic analysis of healthcare big data analytics for efficient care and disease diagnosing
منشور في 2022"…It contains a gigantic amount of data, especially a plethora of data types that has been significantly useful in diverse research domains. In healthcare domain, the researchers use computational devices to extract enriched relevant information from this data and develop smart applications to solve real-life problems in a timely fashion. …"
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Anti-amyloid monoclonal antibody therapies in Alzheimer’s disease – a scoping review
منشور في 2025"…Across the sample, reductions in amyloid burden were frequently reported (10 trials), with a smaller subset of studies reporting significant cognitive and functional improvements (4 trials), primarily lecanemab and aducanumab in addition to one pooled analysis of solanezumab. …"