Pregnancy-related issues in women with multiple sclerosis: an evidence-based review with practical recommendations حسب Beatriz Canibaño (18102676)

"…At short-term, pregnancy leads to a reduction of relapses during the third trimester, followed by an increased risk of relapses during the first three months postpartum. …"

DNA Methylation Biomarkers in Aging and Age-Related Diseases حسب Yasmeen Salameh (8552571)

"…<p dir="ltr">Recent research efforts provided compelling evidence of genome-wide DNA methylation alterations in aging and age-related disease. It is currently well established that DNA methylation biomarkers can determine biological age of any tissue across the entire human lifespan, even during development. …"

Prevalence and attributable health burden of chronic respiratory diseases, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 حسب Joan B Soriano (6458528)

"…In this study, we aimed to characterise the burden of chronic respiratory diseases globally, providing a comprehensive and up-to-date analysis on geographical and time trends from 1990 to 2017. …"

Allergic rhinitis: Disease characteristics and coping measures in Saudi Arabia حسب Almehizia, Abdulmohsin A.

"…Background Despite allergic rhinitis (AR) being a highly prevalent disease, according to literature, it is often underdiagnosed or undertreated. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Breast Disease-Related Educational Outcomes at the University of Florida حسب Lind, D. Scott

"…Limiting breast surgery to a single service does not appear to improve resident accumulation and retention of breast disease-related knowledge. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Unusual Presentation of an Orphan Syndrome Masquerading as Castleman Disease in a Young Adult: Diagnostic Challenges and Clinical Implications: A Case Report حسب Mohamed Gaafar Mohamedali (17945609)

"…<p dir="ltr">IgG4‐related disease (IgG4‐RD) is a rare and diagnostically challenging fibroinflammatory condition characterized by diverse clinical presentations. …"

Potential efficacy of crizanlizumab in treating priapism in sickle cell disease: A case report حسب Mohammed Abdulgayoom (14777791)

"…<h3>Key Clinical Message</h3><p dir="ltr">This report documents the treatment of a 41‐year‐old male with sickle cell disease (SCD) and repeated stuttering priapism using crizanlizumab, which alleviated the priapism but induced a significant vaso‐occlusive crisis during the second infusion. …"

The solution of a recursive sequence arising from a combinatorial problem in botanical epidemiology حسب Al-Sharawi, Ziyad

"…One of the central problems in botanical epidemiology is whether disease spreads within crops in a regular pattern or follows a random process. …"
احصل على النص الكامل

Atypical IgG4‐related disease limited to the sino‐nasal cavity: A case report حسب Ahmed Shaikh (14777452)

"…<p></p><div> <p>Given the overlapping clinical features of sino-nasal immunoglobulin 4-related disease (IgG4-RD) to rhinitis or rhinosinusitis, this paper aims to delineate this rare, isolated manifestation significant to physicians for their daily practice and researchers contributing to this field.…"

Methylomic profiling in trisomy 21 identifies cognition- and Alzheimer’s disease-related dysregulation حسب Larissa Haertle (3864310)

"…Furthermore, T21 patients have a high risk of developing Alzheimer’s disease (AD) early in life, characterized by the presence of senile plaques of amyloid protein and neurofibrillary tangles, leading to neuronal loss and cognitive decline. …"

Forecasting the impact of diabetes mellitus on tuberculosis disease incidence and mortality in India حسب Susanne F Awad (18618622)

"…</p><h3>Conclusions </h3><p dir="ltr">The burgeoning DM epidemic is predicted to become a leading driver of TB disease incidence and mortality over the coming decades. …"

Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis... حسب Marissa B Reitsma (8674341)

"…<h3>Background</h3><p dir="ltr">Ending the global tobacco epidemic is a defining challenge in global health. Timely and comprehensive estimates of the prevalence of smoking tobacco use and attributable disease burden are needed to guide tobacco control efforts nationally and globally.…"

Burden of Transport-Related Injuries in the Eastern Mediterranean Region: A Systematic Analysis for the Global Burden of Disease Study 2017 حسب Saeid Safiri (3713035)

Tolfenamic Acid Derivatives: A New Class of Transcriptional Modulators with Potential Therapeutic Applications for Alzheimer’s Disease and Related Disorders حسب Jaunetta Hill (18255631)

"…<p dir="ltr">The field of Alzheimer’s disease (AD) has witnessed recent breakthroughs in the development of disease-modifying biologics and diagnostic markers. …"

Corneal Confocal Microscopy Identifies Neurodegeneration in Relation to Disease Severity and Neuropathic Symptoms in Rosacea حسب Ioannis N. Petropoulos (8748726)

"…We now seek to demonstrate the utility of CCM to assess neurodegeneration in relation to disease onset and progression, subtypes, and treatment efficacy in patients with rosacea.…"

Rising mortality related to cardiovascular disease and prostate cancer amongst older men across the United States حسب Abdul Ahad (545575)

Islamic Perspectives on Polygenic Testing and Selection of IVF Embryos (PGT-P) for Optimal Intelligence and Other Non–Disease-Related Socially Desirable Traits حسب A. H. B. Chin (17787767)

"…<p dir="ltr">In recent years, the genetic testing and selection of IVF embryos, known as preimplantation genetic testing (PGT), has gained much traction in clinical assisted reproduction for preventing transmission of genetic defects. However, a more recent ethically and morally controversial development in PGT is its possible use in selecting IVF embryos for optimal intelligence quotient (IQ) and other non–disease-related socially desirable traits, such as tallness, fair complexion, athletic ability, and eye and hair colour, based on polygenic risk scores (PRS), in what is referred to as PGT-P. …"

Global, regional, and national burden of household air pollution, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 حسب Fiona B, Bennitt

"…We first estimated the mean fuel type-specific concentrations (in μg/m3) of fine particulate matter (PM2·5) pollution to which individuals using solid fuels for cooking were exposed, categorised by fuel type, location, year, age, and sex. Using a systematic review of the epidemiological literature and a newly developed meta-regression tool (meta-regression: Bayesian, regularised, trimmed), we derived disease-specific, non-parametric exposure–response curves to estimate relative risk as a function of PM2·5 concentration. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Global, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 حسب Valery L Feigin (5320574)

"…The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) aims to provide a standardised and comprehensive measurement of these metrics at global, regional, and national levels. …"

Glucose excursions in type 2 diabetes modulate amyloid-related proteins associated with dementia حسب Abu Saleh Md Moin (6189512)

"…<p dir="ltr">We have reported that hypoglycemia was associated with changes in Alzheimer’s disease (AD)-related proteins in accord with the direct link of cognitive dysfunction to hypoglycemia. …"