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Pregnancy-related issues in women with multiple sclerosis: an evidence-based review with practical recommendations
منشور في 2020"…<h3>Objective</h3><p dir="ltr">To review the current evidence regarding pregnancy-related issues in multiple sclerosis (MS) and to provide recommendations specific for each of them.…"
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Atypical IgG4‐related disease limited to the sino‐nasal cavity: A case report
منشور في 2023"…<p></p><div> <p>Given the overlapping clinical features of sino-nasal immunoglobulin 4-related disease (IgG4-RD) to rhinitis or rhinosinusitis, this paper aims to delineate this rare, isolated manifestation significant to physicians for their daily practice and researchers contributing to this field.…"
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DNA Methylation Biomarkers in Aging and Age-Related Diseases
منشور في 2020"…<p dir="ltr">Recent research efforts provided compelling evidence of genome-wide DNA methylation alterations in aging and age-related disease. It is currently well established that DNA methylation biomarkers can determine biological age of any tissue across the entire human lifespan, even during development. …"
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Prevalence and attributable health burden of chronic respiratory diseases, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017
منشور في 2020"…Smoking was the leading risk factor for chronic respiratory disease-related disability across all regions for men. …"
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Allergic rhinitis: Disease characteristics and coping measures in Saudi Arabia
منشور في 2019"…The sample size comprised 3,458 participants and 2,849 adults had at least one of the four signs of AR, i.e. watery-nose, sneezing, nasal obstruction, itchy nose, watery eyes, in the past year, not related to cold/flu. …"
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Methylomic profiling in trisomy 21 identifies cognition- and Alzheimer’s disease-related dysregulation
منشور في 2019"…Furthermore, T21 patients have a high risk of developing Alzheimer’s disease (AD) early in life, characterized by the presence of senile plaques of amyloid protein and neurofibrillary tangles, leading to neuronal loss and cognitive decline. …"
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Forecasting the impact of diabetes mellitus on tuberculosis disease incidence and mortality in India
منشور في 2019"…Sensitivity analyses were conducted by accommodating less conservative effect sizes for the TB-DM interactions, by factoring the age-dependence of the TB-DM association, and by assuming different TB disease incidence rate trajectories. </p><h3>Results</h3><p dir="ltr"> In 1990, 11.4% (95% uncertainty interval (UI)=6.3%-14.4%) of new TB disease incident cases were attributed to DM. …"
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Molecular Analysis and Conformational Dynamics of Human MC4R Disease-Causing Mutations
منشور في 2022"…A number of mutations have been reported in MC4R that are responsible for causing obesity and related complications. …"
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Corneal Confocal Microscopy Identifies Neurodegeneration in Relation to Disease Severity and Neuropathic Symptoms in Rosacea
منشور في 2025"…We now seek to demonstrate the utility of CCM to assess neurodegeneration in relation to disease onset and progression, subtypes, and treatment efficacy in patients with rosacea.…"
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Potential efficacy of crizanlizumab in treating priapism in sickle cell disease: A case report
منشور في 2024"…However, the potential for infusion‐related adverse events warrants close supervision. …"
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Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis...
منشور في 2021"…We modelled multiple smoking-related indicators from 3625 nationally representative surveys. …"
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Tolfenamic Acid Derivatives: A New Class of Transcriptional Modulators with Potential Therapeutic Applications for Alzheimer’s Disease and Related Disorders
منشور في 2023"…<p dir="ltr">The field of Alzheimer’s disease (AD) has witnessed recent breakthroughs in the development of disease-modifying biologics and diagnostic markers. …"
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Glucose excursions in type 2 diabetes modulate amyloid-related proteins associated with dementia
منشور في 2021"…<p dir="ltr">We have reported that hypoglycemia was associated with changes in Alzheimer’s disease (AD)-related proteins in accord with the direct link of cognitive dysfunction to hypoglycemia. …"
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Changes and trends of pre-hospital emergency disease spectrum in Beijing in the past decade (from 2003 to 2012)
منشور في 2015"…Based on the changes and trends of pre-hospital emergency disease spectrum, it is encouraged to provide specific training program for emergency medical service staff and improve related medical devices. …"
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Efficacy and safety of ensifentrine, a novel phosphodiesterase 3 and 4 inhibitor, in chronic obstructive pulmonary disease: A systematic review and meta-analysis
منشور في 2024"…</p><h3>Conclusion </h3><p dir="ltr">Ensifentrine is associated with improvements in outcomes related to COPD symptoms such as peak FEV-1, morning trough FEV-1 and TDI in the patients suffering from this chronic disease. …"
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Sulforaphane Delays Fibroblast Senescence by Curbing Cellular Glucose Uptake, Increased Glycolysis, and Oxidative Damage
منشور في 2018"…<div><p>Increased cell senescence contributes to the pathogenesis of aging and aging-related disease. Senescence of human fibroblasts in vitro may be delayed by culture in low glucose concentration. …"