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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Reduced graphene aerogels as energy efficient selective oil sorbents
منشور في 2022"…The presence of H<sub>2</sub> significantly decreased the oxygen-containing functional groups in graphene aerogel. …"
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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Evaluation of The Factors Affecting Microplastics and Nanoparticles in Plastic Water Supply Pipes
منشور في 2020احصل على النص الكامل
doctoralThesis -
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How global spine sagittal alignment and spinal degeneration affect locomotive syndrome risk in the elderly
منشور في 2024"…As LS risk increased, LBP prevalence and VAS scores rose, physical abilities, and back muscle strength decreased. TKA showed no variation across groups, while LLA decreased with advancing LS risk stage. …"
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Postprandial lipaemia 10 and 34 hours after playing football: Does playing frequency affect the response?
منشور في 2019"…The aim of the present study was to examine whether playing affects postprandial TG during 1.5 day of reduced activity. …"
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Two-surgeon technique of parenchymal transection contributes to reduced transfusion rate in patients undergoing major hepatectomy
منشور في 2010"…Although transfusion rates can be reduced to almost 0 in uncomplicated hepatectomies, the blood transfusion rates associated with liver resection remain significant at tertiary referral centers, such as ours. …"
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article -
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Methylation at global LINE-1 repeats in human blood are affected by gender but not by age or natural hormone cycles
منشور في 2011"…In vitro results largely confirmed these findings, as neither estrogen nor dihydrotestosterone affected LINE-1 or Alu methylation in Hek293T, HUVEC, or MDA-kb2 cell lines. …"
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احصل على النص الكامل
احصل على النص الكامل
article -
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Reversal of memory and neuropsychiatric symptoms and reduced tau pathology by selenium in 3xTg-AD mice
منشور في 2018"…Chronic sodium selenate treatment efficiently reversed hippocampal-dependent learning and memory impairments, and behavior- and neuropsychiatric-like symptoms in old female 3xTg-AD mice. Selenium significantly decreased the number of aggregated tau-positive neurons and astrogliosis, without globally affecting amyloid plaques, in the hippocampus of 3xTg-AD mice. …"
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An imageable retinoid acid derivative to detect human cancer xenografts and study therapeutic dosing to reduce its toxicity
منشور في 2010"…In addition, retinoic acid can reverse premalignancy, significantly decrease second primary tumors and provide a treatment benefit in head and neck, lung, esophagus, colon and bladder cancer. …"
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احصل على النص الكامل
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احصل على النص الكامل
article -
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Ecotoxicological Assessment of Thermally- and Hydrogen-Reduced Graphene Oxide/TiO<sub>2</sub> Photocatalytic Nanocomposites Using the Zebrafish Embryo Model
منشور في 2019"…However, both nanocomposites should be used with caution at concentration higher than the NOEC (400 mg/L), in particular RGOTi, which significantly (i) caused pericardial and yolk sac edema; (ii) decreased the hatching rate, locomotion, and hematopoietic activities; and (iii) affected the heart rate. …"
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Research on the potential of photovoltaic technologies in reducing energy consumption in an urban mixed use residential community. A Case study for net zero energy community in Dub...
منشور في 2018"…Therefore, the key challenge is to reduce the consumption of fossil fuels which decreases the production of greenhouse gases such as CO2 and CH4 by using renewable energy technologies to provide clean carbon free energy that can combat future energy security challenges. …"
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A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase
منشور في 2015"…The permeability effect of 12-HETE was significantly reduced in NOX2<sup>−/−</sup> mice compared with the WT mice. …"
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Exploring the Role of Perceived Organizational Injustice and Organizational Identification in the Impact of Discretionary HR Practices on Counterproductive Behaviors: Evidence from...
منشور في 2025"…It investigates how customized, flexible HR practices are resource-enhancing tools that decrease workplace deviant behaviors. The study uses survey responses from 214 Lebanese employees working in different sectors to fill a significant knowledge gap in HR studies, primarily focusing on Western business settings. …"
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احصل على النص الكامل
masterThesis -
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