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Olodaterol for the treatment of chronic obstructive pulmonary disease
منشور في 2016"…Olodaterol (Striverdi Respimat, Boehringer Ingelheim), a LABA with high selectivity for β2-adrenergic receptors, is indicated for the treatment of chronic obstructive pulmonary disease (COPD); the recommended dose is 5 µg, to be delivered once daily via the Respimat inhaler. …"
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Morphological changes in amblyopic eyes in choriocapillaris and Sattler’s layer in comparison to healthy eyes, and in retinal nerve fiber layer in comparison to fellow eyes through...
منشور في 2021"…Results The method of measuring reflectivity is good to excellent reliability for all regions of interest except the fourth. The mean reflectivity of the choriocapillaris and Sattler’s layer in amblyopic eyes were significantly lower than in healthy eyes (p = 0.003 and p = 0.008 respectively). …"
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Combined bronchodilators (tiotropium plus olodaterol) for patients with chronic obstructive pulmonary disease
منشور في 2015"…The combination of olodaterol and tiotropium provided additional improvements in lung function greater than monotherapy with each drug alone. Several well-designed randomized trials confirmed that the synergistic effect of both drugs in combination was able to improve lung function and health-related quality of life without a significant increase in adverse effects. …"
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A cross-sectional analysis of zinc and copper levels and their relationship to cardiovascular disease risk markers in Qatar biobank participants
منشور في 2024"…<p dir="ltr">Cardiovascular diseases (CVD) are the leading cause of mortality and morbidity worldwide. …"
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Validation of Polygenic Risk Scores for Coronary Heart Disease in a Middle Eastern Cohort Using Whole Genome Sequencing
منشور في 2022"…Of 400 known genome-wide significant loci, 33 replicated at <i>P</i><10−4. However, the 9p21 locus did not replicate. …"
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Outdoor Air Pollution and Human Health
منشور في 2022"…Air pollution exposure is well known to cause several diseases and pose a greater risk to human health, and most significantly contributes to cardiopulmonary diseases, stroke, lung cancer, and communicable diseases, such as pneumonia. …"
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COVID-19 biomarkers for severity mapped to polycystic ovary syndrome
منشور في 2020"…<p dir="ltr">Large scale multi-omics analysis has identified significant differences in the biomarkers between COVID-19 disease and control subjects [1]. …"
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Hyper-Hypo study: A Retrospective Observational Study of Neonatal Hypoglycemia Related to Maternal Hypertension
منشور في 2023"…On the other hand, neonates of hypertensive mothers administered with methyldopa showed a significant decrease of initial blood glucose reading.…"
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Self-reported awareness and attitude of cancer patients towards clinical nurse coordinators
منشور في 2017"…Responses on Likert scales were converted to percentage mean scores. Results: The overall percentage mean scores ± standard deviation of knowledge was 59 ± 17, perception towards clinical nurse coordinators (79 ± 14) and attitude towards seeking their services (69 ± 16). …"
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Sleeve Gastrectomy in Patients with Type 2 Diabetes: Anthropometric and Cardiometabolic Improvements at 1, 3, 5, 7, and 9 years—Are the Initial Benefits Sustained?
منشور في 2025"…Mean HbA1c significantly decreased from 8.1%preop to 6.77%<sub>year 9</sub>. …"
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Effect of clinical hyperthyroidism and hypothyroidism on patent diabetes. 59 cases
منشور في 1983"…Following treatment of the hyperthyroidism, control was improved in 63%, with an 11-83% (mean 44%) decrease in insulin dosage in 59% of them. …"
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The association between tobacco use and COVID-19 in Qatar
منشور في 2022"…Our data suggests that only smokeless tobacco users may be at an increased risk for severe disease, yet this requires further investigation as other studies have reported smoking to be associated with an increased risk of greater disease severity.…"
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Modification of glucocorticoid effects on body weight gain, plasma lipids by changes in diet composition
منشور في 2003"…Prednisolone-treated groups revealed significantly lower intestinal absorption. However, prednisolone-treated high-carbohydrate (HC) fed rats showed significantly higher weight gain, concomitant with a significant increase in feed efficiency. …"
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Metabolomics in the Diagnosis and Prognosis of COVID-19
منشور في 2021"…With rapidly expanding data on the metabolic profiles of COVID-19 patients with varying degrees of severity, it is likely that metabolomics will play an important role in near future in predicting the outcome of the disease with a greater degree of certainty.</p><h2>Other Information</h2><p dir="ltr">Published in: Frontiers in Genetics<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3389/fgene.2021.721556" target="_blank">https://dx.doi.org/10.3389/fgene.2021.721556</a></p>…"
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Renal Function Decline in Recipients and Donors of Kidney Grafts
منشور في 2015"…Results: Decline in renal function was estimated at 1-year post-transplantation and annually thereafter (median follow-up 8 years, range 3.6-18.3), as the mean of the annualized decrease in the glomerular filtration rate. …"
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L1-CAM knock-down radiosensitizes neuroblastoma IMR-32 cells by simultaneously decreasing MycN, but increasing PTEN protein expression
منشور في 2016"…Tumorsphere formation is one of the indicators of aggressiveness in malignant cancers, which was significantly inhibited in IMR-32 cells after L1-CAM KD or Sutent treatment, however, no synergistic effect was observed with dual treatments, rather L1-CAM KD alone showed a greater inhibition on tumorsphere formation compared to Sutent treatment alone. …"
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Exploring the Fecal miRNA Profile in FMF Patients and the Role of miR-21-5p in Inflammatory Pathways Associated with FMF Pathogenesis
منشور في 2025"…Correlation studies revealed that three anti-inflammatory miRNAs, mir-144-3p, mir-29b- 3p, and mir-374b-5p, were downregulated in M694V homozygous patients compared to those with other genotypes and six miRNAs were higher in patients with greater disease severity. The inhibition of mir-21-5p in LPS-stimulated THP-1 derived macrophages reduced the activation of NF-κB and inflammasome pathways. …"
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Endoscopic ultrasound for early stage esophageal adenocarcinoma
منشور في 2011"…Conclusions Current staging techniques are inadequate for predicting T1-2N0 disease in esophageal adenocarcinoma. Survival is excellent with operation alone in patients with tumors appropriately staged as T1-2N0, although patients with tumors upstaged to greater than T2N0 have significantly worse survival. …"
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Nurses’ work environment and intent to leave in Lebanese hospitals
منشور في 2011"…Results The NWI-R subscale with the lowest mean score related to control. Younger nurses had lower scores on organizational support and career development. …"
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