Civil Unrest and the Poaching of Rhinos in the Kaziranga National Park, India by Lopes, Adrian

“…This paper accounts for a period of civil unrest in Assam, India, which saw a marked increase in rhino poaching. Census data on the greater one-horned rhinoceros (Rhinoceros unicornis) in the Kaziranga National Park in Assam are used to estimate a population growth function. …”
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Solubilization of Protein Aggregates by the Acid Stress Chaperones HdeA and HdeB by Malki, Abderrahim

“…We observed a decrease in the size of protein aggregates in the presence of HdeA and HdeB, from very high molecular mass aggregates to 100–5000-kDa species. Moreover, a marked decrease in the exposed hydrophobicity of aggregated proteins in the presence of HdeA and HdeB was revealed by 1,1′-bis(4-anilino)naphtalene-5,5′-disulfonic acid binding experiments. …”
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Herbal Products and Dietary Supplements by El Khoury, Ghada

“…There has been a marked increase in use of herbal products and dietary supplements (HP/DS) in many developed and developing countries. …”
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Treatment with a Combination of Metformin and 2-Deoxyglucose Upregulates Thrombospondin-1 in Microvascular Endothelial Cells: Implications in Anti-Angiogenic Cancer Therapy by Samson Mathews Samuel (18808246)

“…We observed robust up-regulation of anti-angiogenic thrombospondin-1 (TSP1) and increased TSP1-CD36 co-localization with a marked decrease in the levels of phosphorylated vascular endothelial growth factor receptor-2 (pVEGFR2; Y1175) in 2DG (5 mM) exposed cells treated with metformin (2 mM). …”

DNAJB3 attenuates metabolic stress and promotes glucose uptake by eliciting Glut4 translocation by Abdelilah Arredouani (10914455)

“…Using JNK1- and IKKβ-dependent luciferase reporters, we show a marked decrease in luciferase activity by DNAJB3 in response to PMA and TNF-α that was consistent with a decrease in the translocation of p65/NF-κB to the nucleus in response to LPS. …”

Kefir induces cell-cycle arrest and apoptosis in HTLV-1-negative malignant T-lymphocytes by Rizk, Sandra

“…Upon kefir treatment, a marked increase in cell-cycle distribution was noted in the preG1 phase of CEM and Jurkat cells, indicating the proapoptotic effect of kefir, which was further confirmed by Cell Death Detection ELISA. …”
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A bibliometric analysis of the top cited articles on anterior cruciate ligament reconstruction with anterolateral ligament reconstruction by Osama Z., Alzobi

“…BackgroundIn recent years, there has been a marked increase in research interest in anterior cruciate ligament (ACL) reconstruction combined with anterolateral ligament (ALL) augmentation. …”
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Unexpected adrenal pheochromocytoma associated with a generalized tonic-clonic seizure in a prepubertal boy by Zlatan Zvizdic (9212371)

“…</p><h3>Diagnosis</h3><p dir="ltr">A 24-hour urine collection for catecholamines test showed a marked increase in Vanillylmandelic acid levels (338.9 μmol/L). …”

The impact of the COVID-19 pandemic on the perinatal mental health of women by Tom Farrell (7951295)

“…</p> <h3>Conclusions</h3> <p>Results indicate a marked increase in anxiety and depressive symptoms during the COVID-19 pandemic, among pregnant and puerperal individuals, who constitute a vulnerable group with respect to mental health morbidity. …”

GFRP-Reinforced Concrete Columns: State-of-the-Art, Behavior, and Research Needs by Elkafrawy, Mohamed

“…With a dataset spanning over 250 publications from 1988 to 2024, our findings reveal a marked increase in research interest, particularly in regions like China, Canada, and the United States, highlighting GFRP’s potential as a cost-effective and durable alternative to steel. …”
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Diet-induced mechanical stress promotes immune and metabolic alterations in the Drosophila melanogaster digestive tract by Abeer, Qush

“…Particularly, we show that feeding on MC-containing diet promotes a marked increase in the relative abundance of Leuconostocaceae/Leuconostoc, microbiota-dependent Reactive Oxygen Species (ROS) production, IMD pathway activation, and IMD-dependent elevation in Tk expression. …”
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Diet-induced mechanical stress promotes immune and metabolic alterations in the<i> Drosophila melanogaster </i>digestive tract by Abeer Qush (21383261)

“…Particularly, we show that feeding on MC-containing diet promotes a marked increase in the relative abundance of Leuconostocaceae/Leuconostoc, microbiota-dependent Reactive Oxygen Species (ROS) production, IMD pathway activation, and IMD-dependent elevation in <i>Tk</i> expression. …”

Co-production of high density biomass and high-value compounds via two-stage cultivation of Chlorella vulgaris using light intensity and a combination of salt stressors by Eman A. El-fayoumy (17788952)

“…The combination of 7.5 g L⁻¹NaCl / 7.5 g L⁻¹MgCl₂ also resulted in a marked increase in the protein content (35.32 ± 2.20%) and total carotenoids (0.31 ± 0.03 μg mL⁻¹) as compared to the Controls. …”

Targeting acute myeloid leukemia cells with novel photosensitive ruthenium-based metal-organic compounds. (c2015) by Azar, Daniel Fadi

“…Of the four final complexes Ru-II3, Ru-II2-III, Ru-II-III2 and Ru-III3, only Ru-II3 and Ru-II2-III have shown significant activity against all tested cell lines in the dark, whereas photo-activation against ML2 has shown a marked increase of potency of all four complexes, even those shown to be biologically inert in the dark, reaching IC50 values in the nM range. …”
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Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways by Shehaby, Wassim N.

“…Treatment of HT-29 cells with either fraction markedly decreased the levels of both phosphorylated Erk and Akt. …”
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Recombinant prostate-specific antigen proaerolysin shows selective protease sensitivity and cell cytotoxicity by Abi-Habib, Ralph

“…Recombinant modified proaerolysin had no furin sensitivity and markedly increased prostate-specific antigen sensitivity relative to wild-type proaerolysin. …”
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FLACON: A Deep Federated Transfer Learning-Enabled Transient Stability Assessment During Symmetrical and Asymmetrical Grid Faults by Mohamed Massaoudi (16888710)

“…To avoid the constant adjustment of hyperparameters, the FLACON employs an inductive transfer learning approach for hyperparameter tuning of the pre-trained model, markedly decreasing training time. Extensive experiments on datasets from the IEEE 39-bus system and the IEEE 68-bus system demonstrate FLACON's exceptional accuracy of 98.98% compared to some competitive alternatives.…”

The relationship of soluble neuropilin-1 to severe COVID-19 risk factors in polycystic ovary syndrome by Abu Saleh Md Moin (6189512)

“…Neuropilin-1 (NRP1) is such a co-factor that, when expressed alone shows minimal viral infectivity, but when co-expressed with ACE2 markedly increases viral infectivity [1]. NRP1 is a transmembrane glycoprotein, which is expressed in endothelial cells, and serves as a receptor for vascular endothelial growth factor (VEGF) [2], and both NRP1 and VEGF expression are increased in COVID-19 patients [3,4]. …”

Sulforaphane Delays Fibroblast Senescence by Curbing Cellular Glucose Uptake, Increased Glycolysis, and Oxidative Damage by Florence Hariton (18629764)

“…Cell senescence is associated with a progressive and marked increased rate of glucose metabolism through glycolysis. …”

Synthetic Cannabinoid AB-FUBINACA Negatively Impacted the Male Fertility and Induced Testicular Toxicity by Ayman Alzu’bi (13162392)

“…<h3 dir="ltr">Purpose</h3><p dir="ltr">The recreational use of synthetic cannabinoids (SCs) by adolescents and adults has markedly increased in recent years. Previous studies demonstrated that exposure to SCs is associated with multiple adverse health effects. …”