DNA Methylation Biomarkers in Aging and Age-Related Diseases by Yasmeen Salameh (8552571)

Parallel multi-voltage power minimization in VLSI circuits. (c2013) by Younes, Rabih Halim

Get full text
Get full text

Operation optimization of propane pre-cooled mixed refrigerant LNG Process: A novel integration of knowledge-based and constrained Bayesian optimization approaches by Roba Shady (22048043)

“…In addition, the optimized SEC in this study is 14.5 % to 38.6 % lower than those reported in the literature. At large-scale LNG production (10,000 tons per day), the reduction in the SEC is translated into an 18 MW decrease in compression power, saving approximately 4.7 million $ per year for each C3MR train. …”

Tolfenamic Acid Derivatives: A New Class of Transcriptional Modulators with Potential Therapeutic Applications for Alzheimer’s Disease and Related Disorders by Jaunetta Hill (18255631)

“…<p dir="ltr">The field of Alzheimer’s disease (AD) has witnessed recent breakthroughs in the development of disease-modifying biologics and diagnostic markers. …”

Methylomic profiling in trisomy 21 identifies cognition- and Alzheimer’s disease-related dysregulation by Larissa Haertle (3864310)

“…Performing a targeted association analysis for the significant T21-associated CpG sites in the AgeCoDe cohort, we found that 9 showed significant methylation differences related to AD dementia, including one in the ADAM10 gene. …”

Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis... by Marissa B Reitsma (8674341)

“…Although prevalence of smoking had decreased significantly since 1990 among both males (27·5% [26·5–28·5] reduction) and females (37·7% [35·4–39·9] reduction) aged 15 years and older, population growth has led to a significant increase in the total number of smokers from 0·99 billion (0·98–1·00) in 1990. …”

A genome-wide DNA methylation signature for SETD1B-related syndrome by I. M. Krzyzewska (18614968)

“…Here, we identify a specific hypermethylation signature associated with loss of function mutations in theSETD1Bgene which may be used as an epigenetic marker supporting the diagnosis of syndromicSETD1B-related diseases. …”

A clustering metaheuristic for large orienteering problems by Almiqdad Elzein (13141038)

“…The metaheuristic aims to dramatically improve the computation time of a given Orienteering Problem algorithm without a significant decrease in the solution quality of that algorithm, especially for large Orienteering Problems. …”

Bi-allelic truncating variants in <i>CASP2</i> underlie a neurodevelopmental disorder with lissencephaly by Eyyup Uctepe (19342522)

Joint analysis of diet quality, inflammatory potential of diet and ultra-processed food exposure in relation to chronic respiratory diseases and lung cancer mortality by Tefera Chane, Mekonnen

“…ObjectiveExamined the combined effects of ultra-processed food (UPF), Dietary Inflammatory Index (DII), Healthy Eating Index-2015 (HEI-2015), and Dietary Antioxidant Index (DAI) on mortality from chronic respiratory diseases (CRDs), chronic obstructive pulmonary disease (COPD), and lung cancer. …”
Get full text
Get full text
Get full text

Burden of Transport-Related Injuries in the Eastern Mediterranean Region: A Systematic Analysis for the Global Burden of Disease Study 2017 by Saeid Safiri (3713035)

Expression of CD91 in extracellular vesicles: A potential biomarker for the diagnosis of non-small cell lung cancer by Shayista Akbar (14442117)

Changes and trends of pre-hospital emergency disease spectrum in Beijing in the past decade (from 2003 to 2012) by Tianbing Wang (514759)

“…The top five call demands based on the rank of proportion were trauma related demands(25.4%, including falls（5.0%）, traffic/ transportation incidents(7.2%) and traumatic injuries(13.1%)), sick person(17.7%), heart problems(11.4%), unconscious/fainting（10.0%） and breathing problems（8.1%）Also, they were the top five fastest growing call demands.…”

Correlated levels of cerebrospinal fluid pathogenic proteins in drug-naïve Parkinson’s disease by Hidetomo Murakami (6105284)

“…<h3>Background and aim</h3><p dir="ltr">Toxic oligomeric α-synuclein (αS; O-αS) has been suggested to play a central role in the pathogenesis of Lewy body diseases such as Parkinson’s disease (PD). Cerebrospinal fluid (CSF) levels of αS, O-αS, total and phosphorylated tau, and amyloid β 1–42 (Aβ1–42) are thought to reflect the pathophysiology or clinical symptoms in PD. …”

The solution of a recursive sequence arising from a combinatorial problem in botanical epidemiology by Al-Sharawi, Ziyad

“…One of the central problems in botanical epidemiology is whether disease spreads within crops in a regular pattern or follows a random process. …”
Get full text

A GRASP Approach for Solving Large-Scale Electric Bus Scheduling Problems by Raka Jovanovic (17947838)

“…To be able to solve large problem instances corresponding to real-world applications of the model, a metaheuristic approach is investigated. …”

Cross-sectional proteomic expression in Parkinson's disease-related proteins in drug-naïve patients vs healthy controls with longitudinal clinical follow-up by Ilham Yahya Abdi (17870462)

“…In conclusion, with the use of advance multiplex proteomic technology, a blood-based protein signature profile was identified from serum samples of a well-characterized PD cohort capable of potentially differentiating PD from HC and predicting clinical disease progression of related motor and non-motor PD symptoms. …”

Pregnancy-related issues in women with multiple sclerosis: an evidence-based review with practical recommendations by Beatriz Canibaño (18102676)

“…Pregnancies in MS are not <i>per se</i> high risk pregnancies, and MS does not influence the mode of delivery or anesthesia unless in the presence of significant disability. …”

Molecular analysis of inflammatory diseases by Aya Hamad Almughrbi (21348293)

“…However, researchers nowadays have powerful tools to support this journey to the complexity of the unknown: Next generation Sequencing technologies have provided a plethora of data describing the different OMICs possibly involved in the different inflammatory diseases. Here, we focused on autoinflammatory skin diseases showing the progress of OMICs‐related findings in the understanding of Syndromic HS pathogenesis. …”

Comparative Transcriptome Analysis Reveals That Exendin-4 Improves Steatosis in HepG2 Cells by Modulating Signaling Pathways Related to Lipid Metabolism by Khaoula Errafii (10914446)