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Parallel multi-voltage power minimization in VLSI circuits. (c2013)
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DNA Methylation Biomarkers in Aging and Age-Related Diseases
Published 2020“…<p dir="ltr">Recent research efforts provided compelling evidence of genome-wide DNA methylation alterations in aging and age-related disease. It is currently well established that DNA methylation biomarkers can determine biological age of any tissue across the entire human lifespan, even during development. …”
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Operation optimization of propane pre-cooled mixed refrigerant LNG Process: A novel integration of knowledge-based and constrained Bayesian optimization approaches
Published 2024“…In addition, the optimized SEC in this study is 14.5 % to 38.6 % lower than those reported in the literature. At large-scale LNG production (10,000 tons per day), the reduction in the SEC is translated into an 18 MW decrease in compression power, saving approximately 4.7 million $ per year for each C3MR train. …”
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Breast Disease-Related Educational Outcomes at the University of Florida
Published 2000“…Limiting breast surgery to a single service does not appear to improve resident accumulation and retention of breast disease-related knowledge. …”
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Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis...
Published 2021“…<h3>Background</h3><p dir="ltr">Ending the global tobacco epidemic is a defining challenge in global health. Timely and comprehensive estimates of the prevalence of smoking tobacco use and attributable disease burden are needed to guide tobacco control efforts nationally and globally.…”
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Unusual Presentation of an Orphan Syndrome Masquerading as Castleman Disease in a Young Adult: Diagnostic Challenges and Clinical Implications: A Case Report
Published 2025“…<p dir="ltr">IgG4‐related disease (IgG4‐RD) is a rare and diagnostically challenging fibroinflammatory condition characterized by diverse clinical presentations. …”
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Potential efficacy of crizanlizumab in treating priapism in sickle cell disease: A case report
Published 2024“…<h3>Key Clinical Message</h3><p dir="ltr">This report documents the treatment of a 41‐year‐old male with sickle cell disease (SCD) and repeated stuttering priapism using crizanlizumab, which alleviated the priapism but induced a significant vaso‐occlusive crisis during the second infusion. …”
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The solution of a recursive sequence arising from a combinatorial problem in botanical epidemiology
Published 2013“…One of the central problems in botanical epidemiology is whether disease spreads within crops in a regular pattern or follows a random process. …”
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Atypical IgG4‐related disease limited to the sino‐nasal cavity: A case report
Published 2023“…<p></p><div> <p>Given the overlapping clinical features of sino-nasal immunoglobulin 4-related disease (IgG4-RD) to rhinitis or rhinosinusitis, this paper aims to delineate this rare, isolated manifestation significant to physicians for their daily practice and researchers contributing to this field.…”
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Methylomic profiling in trisomy 21 identifies cognition- and Alzheimer’s disease-related dysregulation
Published 2019“…Furthermore, T21 patients have a high risk of developing Alzheimer’s disease (AD) early in life, characterized by the presence of senile plaques of amyloid protein and neurofibrillary tangles, leading to neuronal loss and cognitive decline. …”
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Tolfenamic Acid Derivatives: A New Class of Transcriptional Modulators with Potential Therapeutic Applications for Alzheimer’s Disease and Related Disorders
Published 2023“…<p dir="ltr">The field of Alzheimer’s disease (AD) has witnessed recent breakthroughs in the development of disease-modifying biologics and diagnostic markers. …”
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Corneal Confocal Microscopy Identifies Neurodegeneration in Relation to Disease Severity and Neuropathic Symptoms in Rosacea
Published 2025“…We now seek to demonstrate the utility of CCM to assess neurodegeneration in relation to disease onset and progression, subtypes, and treatment efficacy in patients with rosacea.…”
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Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss
Published 2018“…The disease has a multifactorial etiology with both environmental and genetic factors involved being largely unknown. …”
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A clustering metaheuristic for large orienteering problems
Published 2022“…The metaheuristic aims to dramatically improve the computation time of a given Orienteering Problem algorithm without a significant decrease in the solution quality of that algorithm, especially for large Orienteering Problems. …”
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Islamic Perspectives on Polygenic Testing and Selection of IVF Embryos (PGT-P) for Optimal Intelligence and Other Non–Disease-Related Socially Desirable Traits
Published 2023“…<p dir="ltr">In recent years, the genetic testing and selection of IVF embryos, known as preimplantation genetic testing (PGT), has gained much traction in clinical assisted reproduction for preventing transmission of genetic defects. However, a more recent ethically and morally controversial development in PGT is its possible use in selecting IVF embryos for optimal intelligence quotient (IQ) and other non–disease-related socially desirable traits, such as tallness, fair complexion, athletic ability, and eye and hair colour, based on polygenic risk scores (PRS), in what is referred to as PGT-P. …”
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Glucose excursions in type 2 diabetes modulate amyloid-related proteins associated with dementia
Published 2021“…<p dir="ltr">We have reported that hypoglycemia was associated with changes in Alzheimer’s disease (AD)-related proteins in accord with the direct link of cognitive dysfunction to hypoglycemia. …”
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Changes and trends of pre-hospital emergency disease spectrum in Beijing in the past decade (from 2003 to 2012)
Published 2015“…<h3 dir="ltr">Backgrounds</h3><p dir="ltr">Pre-hospital emergency call is a crucial index to indicate emergency disease spectrum. …”
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Pregnancy-related issues in women with multiple sclerosis: an evidence-based review with practical recommendations
Published 2020“…</p><h3>Results</h3><p dir="ltr">MS has no effect on fertility, pregnancy or fetal outcomes, and pregnancies do not affect the long-term disease course and accumulation of disability. There is a potential risk for relapse after use of gonadotropin-releasing hormone agonists during assisted reproduction techniques. …”