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Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels
Published 2024“…Additionally, a decrease in glycochenodeoxycholic acid levels was also triggered by treatment with AuNPs, suggesting modulation of bile acid metabolism with potential effects on lipid homeostasis. …”
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Abiotic stress applied to Tetraselmis subcordiformis reveals enhanced metabolic responses and increased production of Omega-3 fatty acids: A Metabolomic approach
Published 2023“…Moreover, nitrogen content increase by 20 % and 5.8 % for 100 PSU and N-starvation stress. …”
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Abiotic stress applied to Tetraselmis subcordiformis reveals enhanced metabolic responses and increased production of Omega-3 fatty acids: A Metabolomic approach
Published 2024“…Moreover, nitrogen content increase by 20 % and 5.8 % for 100 PSU and N-starvation stress. …”
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A clustering metaheuristic for large orienteering problems
Published 2022“…The metaheuristic aims to dramatically improve the computation time of a given Orienteering Problem algorithm without a significant decrease in the solution quality of that algorithm, especially for large Orienteering Problems. …”
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Asphalt modification with polyphosphoric acid
Published 2017“…The results demonstrate that a level of polyphosphoric acid near 0.5 percent works well for most binders.…”
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6
A GRASP Approach for Solving Large-Scale Electric Bus Scheduling Problems
Published 2021“…To be able to solve large problem instances corresponding to real-world applications of the model, a metaheuristic approach is investigated. …”
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Metabolic Signatures of Type 2 Diabetes Mellitus and Hypertension in COVID-19 Patients With Different Disease Severity
Published 2022“…</p><p><br></p><h3>Results</h3><p dir="ltr">Reduced levels of various triacylglycerols were observed with increased disease severity in the diabetic patients, including those containing palmitic (C16:0), docosapentaenoic (C22:5, DPA), and docosahexaenoic (C22:6, DHA) acids (FDR < 0.01). …”
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Cyclosporine lymphocyte maximum level
Published 2005“…No significant difference was observed among the 3 groups with regard to CsA dosage, C0, Cmax, mycophenolate mofetil (MMF) dosage, and mycophenolic acid (MPA) plasma levels. CsA LTmL closely correlated in an exponential (R2 = 0.98) and linear (R2 = 0.35) fashion with LC and hematocrit level, respectively. …”
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Shear Strength Behaviors of Tire Shred-Dune Sand Admixtures
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Targeting Breast Cancer Using Hyaluronic Acid-Conjugated Liposomes Triggered with Ultrasound
Published 2021“…HA conjugation to the liposomes resulted in a significant increase in calcein uptake by the breast cancer cell line MDA-MB-231 known for its CD44 (HA receptor) overexpression, while such an effect was not recorded with NIH-3T3, an embryonic mouse fibroblast, with low levels of CD44 expression. …”
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A review on the solid–liquid–vapor phase equilibria of acid gases in methane
Published 2023“…<p></p><div> <p>In spite of the increasing levels of greenhouse gases in the atmosphere, and their impact on the environment, the demand for natural/biogas will increase significantly in the coming few decades. …”
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Synergistic Effect of Epigenetic Inhibitors Decitabine and Suberoylanilide Hydroxamic Acid on Colorectal Cancer In vitro
Published 2019“…Furthermore, the combination therapy upregulates protein expression levels of pro-apoptotic proteins Bax, p53 and cytochrome c, downregulates the expression of antiapoptotic Bcl-2 protein and increases the cleavage of procaspases 8 and 9; this suggests that the combination activates apoptosis via both the intrinsic and extrinsic pathways. …”
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Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy
Published 2019“…Impaired protein degradation and increased levels of α-synuclein may trigger a pathological aggregation <i>in vitro</i> and <i>in vivo</i>. …”
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The ortholog of human ssDNA-binding protein SSBP3 influences neurodevelopment and autism-like behaviors in <i>Drosophila melanogaster</i>
Published 2023“…One such gene is the single-stranded DNA-binding protein 3 (<i>SSBP3</i>) and its Drosophila melanogaster ortholog is called sequence-specific single-stranded DNA-binding protein (<i>Ssdp</i>). …”
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Parallel multi-voltage power minimization in VLSI circuits. (c2013)
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20
Operation optimization of propane pre-cooled mixed refrigerant LNG Process: A novel integration of knowledge-based and constrained Bayesian optimization approaches
Published 2024“…In addition, the optimized SEC in this study is 14.5 % to 38.6 % lower than those reported in the literature. At large-scale LNG production (10,000 tons per day), the reduction in the SEC is translated into an 18 MW decrease in compression power, saving approximately 4.7 million $ per year for each C3MR train. …”