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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…From this and previous transcriptomic studies, signaling involved in enhanced removal of MG-modified protein is likely increased HSPB1-directed HUWE1 ubiquitination through eIF2α-mediated, ATF5-induced increased expression of HSPB1. …”
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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
Published 2021“…Recent studies specified the overexpression of V-domain Ig suppressor of T-cell activation (VISTA) and Aryl Hydrocarbon Receptor (AHR) in melanoma. …”
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Ferroelectric Properties and Electrocaloric Effect in Dy2O3 Substitution on Lead-Free (Na0.5 Bi0.5)0.94 Ba0.06TiO3 Ceramic
Published 2023“…Using the direct EC measurement, the ceramic corresponding to y = 0.02 exhibited a significant EC response, where ΔT = 1.2 K under 5 kV/mm. The incorporation of Dy was found to enhance the EC responsivity coefficient ζ = iT/ΔE), with a best value of ζ = 0.24 K.mm/kV for y = 0.02.…”
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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov...
Published 2023“…We measured the levels of neutralizing total antibodies (NtAbs), anti-S-RBD IgG, and anti-S1 IgA titers among VN and NI up to ∼10 months from administration of the first dose, and up to ∼7 months from SARS-CoV-2 infection, respectively. …”
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Global, regional, and national burden of household air pollution, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
Published 2025“…The rate of HAP-attributable DALYs was higher for males (1530·5, 1023·4–2263·6) than for females (1318·5, 866·1–1977·2). …”
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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
Published 2025“…We envisage that the NB2E3 nanobody-2× Mpro biosensor engineered here will be useful in drug discovery and functional characterization of Mpro mutants in newly emerging SARS-CoV-2 variants as well as in detecting SARS-CoV-2 infection in a point-of-care testing (POCT) format.…”
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Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants
Published 2017“…Global age-standardised prevalence of raised blood pressure was 24·1% (21·4–27·1) in men and 20·1% (17·8–22·5) in women in 2015. Mean systolic and mean diastolic blood pressure decreased substantially from 1975 to 2015 in high-income western and Asia Pacific countries, moving these countries from having some of the highest worldwide blood pressure in 1975 to the lowest in 2015. …”
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Exploring Beyond Numeric Weight Loss: The Metabolic Effects of Semaglutide.
Published 2025“…Also, it enhanced glycemic control, as evidenced by significant reductions in hemoglobin A1C (HbA1c) with the 0.5 mg and 1.0 mg doses. From a baseline range of 8.1–8.7%, 0.5mg dose lowered HbA1c by 1.2–1.5%, while the 1.0 mg dose reduced it by 1.4–1.8%. …”
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Impact of the COVID-19 pandemic on sexually transmitted infection testing and diagnosis in Lebanon: A retrospective chart review
Published 2024“…Post-COVID-19 onset, 1.7 % of patients tested positive for any STI compared with 1.1 % pre-COVID-19 onset (OR: 1.5, 95%CI: 0.8–2.7). Close to 90 % of all positive diagnoses were among MSM. …”
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Human health risks associated with the consumption of groundwater in the Gaza Strip
Published 2023“…On the other hand, nitrate (NO3) decreased by 30 %, due to expansion of the sewer network and decrease in the number and distribution of septic tanks. …”
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Effect of sintering temperature of NBT–6BT lead-free ceramics on the structural, ferroelectric and piezoelectric properties
Published 2022“…It is found that the optimal ferroelectric and piezoelectric values were obtained at 1150 °C (P r = 27 µC/cm 2 , E c = 3.89 kV/mm and d 33 = 110 pC/N). …”
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Empirical evaluation of change in crash risk due to lane marking reallocation: A case study in Kochi City, Japan
Published 2023“…In addition, the results indicate that the PICUD value tends to decrease (i.e., the crash risk tends to increase) with increasing speed of the following vehicle relative to the leading vehicle. …”
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Unraveling the future productivity burden of cardiovascular disease in Qatar: Investigating the modifiable risk factors control in type 2 diabetes
Published 2025“…The financial value of PALYs was determined based on the gross domestic product (GDP) per full-time worker (i.e. US$80,573). The base-case model estimated the productivity burden of CVD, and interventional scenarios were simulated to assess potential gains resulting from improved control of modifiable risk factors, including reduced incidence of T2D, lower systolic blood pressure (SBP), decreased number of smokers, and reduced total cholesterol. …”
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Modeling the influence of daily temperature and precipitation extreme indices on vegetation dynamics in Katsina State using statistical downscaling model (SDM)
Published 2023“…Tmax and Tmin were projected under low emissions at 20.1 0C and 14.25 0C (RCP2.6), 20.13 °C and 14.26 0C (RCP4.5), and 20.15 0C and 14.27 0C (RCP8.5) respectively. …”
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Methane production enhancement from Tetraselmis biomass co-digestion using frying oil residue as co-substrate and ultrasonication as pretreatment
Published 2023“…Interestingly, compared to untreated Tetraselmis biomass, sonication pretreatment using specific energy of 1.6 kJ/g VS significantly improved specific methane production by 60.5%. However, increasing specific energy sonication to 3.2 kJ/g VS decreased the positive energy balance of whole process from 8.6 to 5.5 ± 0.3 kJ/g VS. …”
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Influence of temperature on tire-pavement noise in hot climates: Qatar case
Published 2021“…This temperature correction factor is developed based on the local environment (temperature varying from 5 °C to 35 °C) and generally varies with different pavements. …”
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Influence of shelf-life duration on mechanical, thermal and shape recovery motion derivatives of shape memory polyurethane
Published 2024“…The results indicated that tensile and flexural strength decreased by 35.16 % and 29.3 % respectively, from S1 to S10. …”
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Regional variations in incidence of surgical site infection and associated risk factors in women undergoing cesarean section: A systematic review and Meta-Analysis
Published 2025“…The SSI incidence in LMICs was 8.0 % (95 % CI: 6.0 %–10.0 %) with moderate certainty, while the incidence in HICs was 5.0 % (95 % CI: 4.0 %–7.0 %) with low certainty. …”
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Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 co...
Published 2024“…Non-communicable diseases contributed 1·73 billion (95% UI 1·54–1·94) DALYs in 2021, with a decrease in age-standardised DALY rates since 2010 of 6·4% (95% UI 3·5–9·5). …”
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