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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…This may be achieved by decreasing protein glycation by the reactive metabolite, methylglyoxal (MG). …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…This may be achieved by decreasing protein glycation by the reactive metabolite, methylglyoxal (MG). …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…Specifically, the N501Y mutation in the S1 spike receptor binding domain (S1-RBD) of these variants have been reported to increase its affinity for ACE2, although the basis for this is not entirely clear yet. …”
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Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex
Published 2022“…<p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences <a href="https://dx.doi.org/10.3389/fmolb.2022.846996" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.846996</a>, published online 22 July 2022.…”
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Effects of vitamin E derivatives on the proliferation of KG-1 leukemic cells in vitro
Published 2017“…XTT cell viability assay, which detects the presence of metabolically active cells, was used to assess cell proliferation. A decrease in proliferation of KG-1 cells was observed upon treatment with both forms of vitamin E derivatives; however, β-T3 was more potent than γ-T3 in promoting cell death with lower IC50 values. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…PP2A, GSK3β and Tau reside together in a complex, which facilitates their interaction and (dys)-function as has been reported for several neurological disorders. …”
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eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways
Published 2018“…Furthermore, we show that hippuristanol perturbs the activation of the STAT3 pathway and expression of STAT3-gene targets such as IL-6. The decreased activation of STAT3, which resulted from a decrease in STAT3 protein expression, was due to the inhibition of STAT3 translation as there were no changes in STAT3 mRNA levels. …”
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Addressing Challenges of Distance Learning in the Pandemic with Edge Intelligence Enabled Multicast and Caching Solution
Published 2022“…Due to the closure of educational institutes, work and learn from home methods have burdened the network resources and considerably decreased a viewer’s Quality of Experience (QoE). The situation calls for innovative techniques to handle the surging load of video traffic on cellular networks. …”
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Application of Fe<sub>3</sub>O<sub>4</sub> magnetite nanoparticles grafted in silica (SiO<sub>2</sub>) for oil recovery from oil in water emulsions
Published 2021“…An excellent %<sub>hdem</sub> 90% was achieved C<sub>oil</sub> in the range 50 e2000 mg/L. Using an MD<sub>dose</sub> as low as 10 mg/L attained a %<sub>hdem</sub> in the range of 93% - 4.3% for O/W mixtures with C<sub>oil</sub> < 2000 mg/L, which slightly decreased to ~90% for higher concentrations. …”
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Notes total mesorectal excision (TME) for patients with rectal neoplasia
Published 2014“…This approach may lead to reduced postoperative pain, decreased hernia formation and improved cosmesis when compared to standard laparoscopy. …”
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Effect of Girder Damage on the Structural Behavior of Slab-on-Girder Bridges
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