Published 2005
“…This channel is gated by cAMP and thus allow to follow cAMP dynamics by recording the associated cationic current (ICNG) with the whole cell patch
clamp technique 24 h after infection. Cumulative concentrationresponse curve to the non-selective
E-adrenergic agonist isoprenaline (Iso) indicated
a 33%
decrease of the maximal cAMP accumulation produced by Iso while the effect of the hydrosoluble forskolin analog, L-858051 at
a saturating concentration (100 µM) was unchanged between the two groups. …”
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