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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
Published 2025“…We envisage that the NB2E3 nanobody-2× Mpro biosensor engineered here will be useful in drug discovery and functional characterization of Mpro mutants in newly emerging SARS-CoV-2 variants as well as in detecting SARS-CoV-2 infection in a point-of-care testing (POCT) format.…”
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A GRASP Approach for Solving Large-Scale Electric Bus Scheduling Problems
Published 2021“…The results of the conducted computational experiments indicate that an increase in infrastructure investment through high speed chargers can significantly decrease the size of the necessary fleets. The results also show that high speed chargers have a more significant impact than an increase in battery sizes of the EBs.…”
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Second-law-based performance evaluation of cooling towers and evaporative heat exchangers
Published 2020“…For the different input variables investigated, efficiencies were, almost always, seen to increase or decrease monotonically. We notice that an increase in the inlet wet bulb temperature invariably increases the second-law efficiency of all the heat exchangers. …”
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Dynamics of Neisseria gonorrhoeae transmission among female sex workers and clients: A mathematical modeling study
Published 2024“…Increasing condom use from 10 % to 50 % lowers NG prevalence among FSWs, clients, and their spouses from 12.2 % to 6.4 %, 1.2 % to 0.5 %, and 0.4 % to 0.2 %, respectively. …”
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Association Between Three-Months Vitamin D Supplementation and Depressive Symptomatology incidence among Saudi Arabian Adults
Published 2022“…The mean baseline 25(OH)D3 concentration was 16.92±7.23ng/ml in the vitamin D group and 16.44±5.91 ng/ml in the control group (p =0.76). …”
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Interleukin-35 and Thymoquinone nanoparticle-based intervention for liver protection against paracetamol-induced liver injury in rats
Published 2023“…Group IV (PAR) received 600 mg/kg of PAR orally; V (PAR + IL-35) and VI (PAR + TYHO); rats received 600 mg/kg of PAR orally and i.p injection of IL-35 (200 ng/kg) or THYO (0.5 mg/kg), respectively. …”
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Improved properties and salt rejection of polysulfone membrane by incorporation of hydrophilic cobalt-doped ZnO nanoparticles
Published 2024“…<p dir="ltr">In this study, the nanoparticles (NPs) of ZnO and Co<sup>2+</sup> ions doped ZnO (doped ZnO) were incorporated into a matrix of polysulfone (PSf) membranes to enhance their surface properties prepared using a simple wet phase inversion technique. The hybrid PSf membranes were fabricated with 0.5 wt. % of ZnO and doped ZnO NPs. …”
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Comprehensive thermoeconomic, exergoeconomic, and optimization analyses of direct oxy‐combustion supercritical CO<sub>2</sub> intercooled and reheated cycles under design and off‐d...
Published 2022“…At optimized conditions (<i>P</i><sub>c,o</sub> = 30 MPa, Pc,o = 8 MPa, TIT = 744°C, CIT = 30°C [wet‐cooling]), the ICC shows superior energetic performance (52.08%) compared to 47.97% for DRC, 49.20% for PIC, and 48.62% for RHC. …”
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An Experimental Investigation of the Effects of Dressing and Grinding Parameters on Sustainable Grinding of Inconel 738 Used for Automated Manufacturing
Published 2023“…The results indicate that the MQL technique increases the grinding performance of Inconel 738 by reducing ground workpiece surface roughness and decreasing the coolant–lubricant consumption comparing to the conventional wet grinding process. …”
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The effects of long-term testosterone treatment on endocrine parameters in hypogonadal men: 12-year data from a prospective controlled registry study
Published 2022“…This was accompanied by an increase in estradiol levels by 14.9 pmol/L (<i>p</i> < 0.0001), and decreases in progesterone (0.2 ng/mL, <i>p</i> < 0.0001), LH (10.4 U/L, <i>p</i> < 0.0001) and FSH (8.4 U/L, <i>p</i> < 0.0001) were demonstrated at 12-years. …”
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Impacts of twenty years of experimental warming on soil carbon, nitrogen, moisture and soil mites across alpine/subarctic tundra communities
Published 2022“…Long-term warming also caused loss of nitrogen, carbon and moisture from the mineral soil layer in mesic meadow, but not in wet meadow or heath or from the organic soil layer. …”
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The Effect of Atorvastatin (and Subsequent Metformin) on Adipose Tissue Acylation-Stimulatory-Protein Concentration and Inflammatory Biomarkers in Overweight/Obese Women With Polyc...
Published 2019“…</p><h3>Results</h3><p dir="ltr">There was significant reduction in ASP (156.7 ± 16.2 vs. 124.4 ± 14.8 ng/ml p <0.01), IL-6 (1.48 ± 0.29 vs.0.73 ± 0.34 pg/ml p = 0.01) and MCP-1 (30.4 ± 4.2 vs. 23.0 ± 4.5 pg/ml p = 0.02) after 12 weeks of atorvastatin that was maintained subsequently with 12 weeks treatment with metformin. …”
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Seasonal variations of trace metal chemical forms in bed sediments of a karstic river in Lebanon
Published 2015“…Climate is “Mediterranean”: wet winters and dry summers. Active sediment flushing is restricted to winter high discharge episodes. …”
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Adopting Geophysical Testing Techniques in Geotechnical Investigation and Shallow Foundation Design
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