A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate by Geethakumari, Anupriya M

“…We envisage that the NB2E3 nanobody-2× Mpro biosensor engineered here will be useful in drug discovery and functional characterization of Mpro mutants in newly emerging SARS-CoV-2 variants as well as in detecting SARS-CoV-2 infection in a point-of-care testing (POCT) format.…”
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Mercury pollution in doha (Qatar) coastal environment by Al-Madfa, H.

“…1). Organic Hg (0.6 ng L?1) contributed only 5.0% of total Hg. Mercury showed a strong tendency to be associated with suspended matter in Doha coastal waters, as it represented about 73.0% of the total. …”
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Dynamics of Neisseria gonorrhoeae transmission among female sex workers and clients: A mathematical modeling study by Houssein H., Ayoub

“…Increasing condom use from 10 % to 50 % lowers NG prevalence among FSWs, clients, and their spouses from 12.2 % to 6.4 %, 1.2 % to 0.5 %, and 0.4 % to 0.2 %, respectively. …”
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Investigation of Spatiotemporal Variability of Microplastics in Qatar's Cstal Environment by Ben-Hamadou, Radhouane

“…There has been a tremendous proliferation in plastic production in the last five decades due to its low cost and versatile applications. …”
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Differentiation of human olfactory bulb-derived neural stem cells toward oligodendrocyte. by Marei, Hany E

“…The differentiation medium, containing cAMP, PDGFA, T3, and all-trans-retinoic acid (ATRA), promotes OBNSCs to generate mostly oligodendrocytes (OLs) displaying morphological changes, and appearance of long cytoplasmic processes. OBNSCs showed, after 5 days in OLs differentiation medium, a considerable decrease in the number of nestin positive cells, which was associated with a concomitant increase of NG2 immunoreactive cells and few O4(+)-OPCs. …”
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Effect of Hyperglycemia on eNOS function in EPCs by Elshiekh, Duaa Ibnomer

“…Cells were treated with normal glucose (NG, 5.5mM) and high glucose (HG, 25mM) media for 3 & 6 days, and the effect on eNOS and Akt phosphorylation were assessed using western blot. …”
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Reinforcement of polyacrylamide-co-tert-butyl acrylate base gel using nanosilica for conformance control at low and high reservoir temperatures by Shamlooh M.

“…In this study, different ratios of polymer to crosslinker were investigated to choose the optimum combination. Then, nanosilica (NS) with different sizes (20, 50 and 85 nm) was added to the polymeric formulation with the inorganic crosslinker (CrAc3) to study the effect of silica content and size on gel strength. …”
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Roadmap toward energy-positive upfront nitrogen removal process in baseload LNG plant by Mkacher, Hajer

“…The results show that UNrem of 87.5% from the NG feed can reduce the total power requirements by 0.24%, increase the production flow rate by 4.4%, and decrease the exergy losses by 0.23% compared with the base case. …”
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PERFORMANCE OPTIMIZATION OF PROPANE PRE-COOLED MIXED REFRIGERANT (C3MR) PROCESS FOR NATURAL GAS LIQUEFACTION by SHADY, ROBA TAWFIK SAAD MOHAMED

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Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2. by P, Sneha

“…Molecular docking analysis revealed a decrease in interaction between the protein and ATP in all the 3 mutations, and molecular dynamic simulations of 50 ns showed a loss of stability and compactness in the mutant proteins. …”
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RIGOROUS SIMULATION AND OPTIMIZATION OF THE COLD SECTION IN A REAL LNG PLANT: UPFRONT NITROGEN REMOVAL AS PROCESS ENHANCING CONCEPT by MKACHER, HAJER

“…Compared with baseline operation, removing up to 87.5% of nitrogen from the feed was found optimal as it decreases the total power requirement by 0.24 MW and increases the LNG product flow rate by 4.4 %, while exergy loss decreased by 7.08 MW. …”
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The Expression of TBC1 Domain Family, Member 4 (TBC1D4) in Skeletal Muscles of Insulin-Resistant Mice in Response to Sulforaphane by Rizk, Nasser M

“…Methodology: C57BL/6 mice (n=20) were fed with a high fat diet (60%) for 16 weeks to generate diet induced obese (DIO) mice with body weights between 45–50 gm. Thereafter, DIO mice received either SFN (5mg/kg BW) (n=10) or vehicle (n=10) as controls daily by intraperitoneal injections for four weeks. …”
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Effect of Seagrass Liquid Extracts on Bell Pepper (Capsicum annuum) Under Salt stress Conditions. by Al-qahtani, Noora Saad

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INVESTIGATION OF SPATIOTEMPORAL VARIABILITY AND CONTAMINATION OF PLASTIC MARINE DEBRIS IN QATAR’S COASTAL WATERS by Abayomi, Oyebamiji Abib

“…There has been a tremendous proliferation in plastic production in the last five decades due to its low cost and versatile applications. …”
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Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach by P., Sneha

“…Triplicate runs of molecular dynamic (MD) simulations (50ns) revealed smaller changes in patterns of deviation, fluctuation, and compactness, in complexes containing the R131Q and R131W mutations, compared to complexes containing the R203C mutant complex. …”
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A computational model to predict the structural and functional consequences of missense mutations in O6-methylguanine DNA methyltransferase by Thirumal Kumar, D

“…Considering true positives, true negatives, false positives, and false negatives, three mutations (Y114E, R128G, and C145A) showed "loss of DNA repair activity," and were analyzed further using molecular dynamics simulations (MDS) using GROMACS for 50ns. MDS run showed that the C145A mutant demonstrated higher structural deviation, decreased compactness, and the binding patterns. …”
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Freezing-Based Acid Gas Removal and Its Integration with the Cold Section in an LNG Plant by Pal, Ajinkya

“…The feed-to-fuel (FFF) ratio decreases from 6.94% for the base process to 5.7% for the integrated process.…”
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Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021 by Stein Emil, Vollset

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Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021 by Stein Emil, Vollset

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Comparing Methods for Induction of Insulin Resistance in Mouse 3T3-L1 Cells. by Al-Jaber, Hend

“…These factors included 2.5nM tumor necrosis factor-alpha (TNFα), 20 ng/ml interleukin-6 (IL-6), 10 micromole 4-hydroxynonenal (4HNE), and high insulin (HI) at a concentration of 100nM. …”
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