Gene-specific machine learning model to predict the pathogenicity of BRCA2 variants by Mohannad N. Khandakji (13885434)

“…<h3>Background</h3><p dir="ltr">Existing BRCA2-specific variant pathogenicity prediction algorithms focus on the prediction of the functional impact of a subtype of variants alone. …”

Genetic and heuristic algorithms for regrouping service sites. (c2000) by Tabbara, Hiba

Get full text
Get full text

Defense against adversarial attacks: robust and efficient compressed optimized neural networks by Insaf Kraidia (19198012)

“…A cumulative updating loss function was employed for overall optimization, demonstrating remarkable superiority over traditional optimization techniques. …”

Cortical EEG Source Localization of Focal Epilepsy by Siyam, Wisal Elfatih Mohamed

Get full text

Single-Cell Transcriptome Analysis Highlights a Role for Neutrophils and Inflammatory Macrophages in the Pathogenesis of Severe COVID-19 by Hibah Shaath (5599658)

“…Further analyses revealed genes associated with the inflammatory response and chemotaxis of myeloid cells, phagocytes, and granulocytes, among the top activated functional categories in BAL from severe COVID-19-affected patients. …”

Optimizing clopidogrel dose response by Saab, Yolande B.

“…Purpose Response to clopidogrel varies widely with nonresponse rates ranging from 4% to 30%. A reduced function of the gene variant of the CYP2C19 has been associated with lower drug metabolite levels, and hence diminished platelet inhibition. …”
Get full text
Get full text
Get full text
Get full text

Autonomous Robot Navigation Based On Recurrent Neural Networks by Al-Sagban, Mariam Qusai

Get full text

The Use of Enumerative Techniques in Topological Optimization of Computer Networks Subject to Fault Tolerance and Reliability by Abd-El-barr, Mostafa

“…A fault tolerant network is able to function even in the presence of some faults in the network. …”
Get full text

Prediction of biogas production from chemically treated co-digested agricultural waste using artificial neural network by Fares Almomani (12585685)

“…<p dir="ltr">The present study evaluates the effect of co-digestion of agricultural solid wastes (ASWs), cow manure (CM), and the application of chemical pre-treatment with NaHCO₃ on the performance of anaerobic digestion (AD) process. …”

Detecting protein complexes in protein interaction networks using Mapper and Graph Convolution Networks by Daou, Leonardo

Get full text
Get full text
Get full text

Large language models for code completion: A systematic literature review by Rasha Ahmad Husein (19744756)

“…This is achieved by predicting subsequent tokens, such as keywords, variable names, types, function names, operators, and more. Different techniques can achieve code completion, and recent research has focused on Deep Learning methods, particularly Large Language Models (LLMs) utilizing Transformer algorithms. …”

Blood-Based Proteomic Profiling Identifies Potential Biomarker Candidates and Pathogenic Pathways in Dementia by Hanan Ehtewish (17149825)

“…We used a high-throughput proximity extension immunoassay to quantify 1090 proteins in 122 participants (22 with dementia, 64 with mild cognitive impairment (MCI), and 36 controls with normal cognitive function). Limma-based differential expression analysis reported the dysregulation of 61 proteins in the plasma of those with dementia compared with controls, and machine learning algorithms identified 17 stable diagnostic biomarkers that differentiated individuals with AUC = 0.98 ± 0.02. …”

Single-Cell Transcriptome Analysis Revealed Heterogeneity and Identified Novel Therapeutic Targets for Breast Cancer Subtypes by Radhakrishnan Vishnubalaji (3563306)

“…Differential expression and gene set enrichment analysis in TNBC revealed enrichment in the cycle and mitosis functional categories in FDPShigh, while ENO1high was associated with numerous functional categories, including cell cycle, glycolysis, and ATP metabolic processes. …”

Cohen syndrome and early-onset epileptic encephalopathy in male triplets: two disease-causing mutations in VPS13B and NAPB by Alice AbdelAleem (17753799)

“…Homozygosity mapping of ES data of this consanguineous family revealed multiple chromosomal regions of homozygosity stretches with the residing of VPS13B (chr8: 100830758G > A) and NAPB (Chr20: 23,375,774 A > C) variants within the largest homozygous blocks further supporting the disease-genes causal role. Interestingly, the functions of the two proteins; VPS13B, a transmembrane protein involved in intracellular protein transport, and SNAP-beta involved in neurotransmitters release at the neuronal synaptic complexes, have been associated with Golgi-mediated vesicular trafficking. …”

DeepRaman: Implementing surface-enhanced Raman scattering together with cutting-edge machine learning for the differentiation and classification of bacterial endotoxins by Samir Brahim, Belhaouari

“…ObjectiveThis study utilized various classical machine learning techniques, such as support vector machines, k-nearest neighbors, and random forests, in conjunction with a modified deep learning approach called DeepRaman. These algorithms were employed to distinguish and categorize bacterial endotoxins, following appropriate spectral pre-processing, which involved novel filtering techniques and advanced feature extraction methods. …”
Get full text
Get full text
Get full text

Exploring the Dynamic Interplay of Deleterious Variants on the RAF1–RAP1A Binding in Cancer: Conformational Analysis, Binding Free Energy, and Essential Dynamics by Abbas Khan (5141000)

“…Hence, the current study focuses on the screening of clinically reported substitutions in the <i>RAF1</i> and <i>RAP1A</i> genes using predictive algorithms integrated with all‐atoms simulation, essential dynamics, and binding free energy methods. …”

Copy number variations in the genome of the Qatari population by Khalid A. Fakhro (3158862)

“…Up to 40 % of all CNVs affected genes, including novel CNVs affecting Mendelian disease genes, segregating at different frequencies in the 3 major Qatari subpopulations, including those with Bedouin, Persian/South Asian, and African ancestry. …”