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b function » _ functional (Expand Search)
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A New Penalty Function Algorithm For Convex Quadratic Programming
Published 2020“…In this paper, we develop an exterior point algorithm for convex quadratic programming using a penalty function approach. …”
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Gene-specific machine learning model to predict the pathogenicity of BRCA2 variants
Published 2022“…<h3>Background</h3><p dir="ltr">Existing BRCA2-specific variant pathogenicity prediction algorithms focus on the prediction of the functional impact of a subtype of variants alone. …”
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Cohen syndrome and early-onset epileptic encephalopathy in male triplets: two disease-causing mutations in VPS13B and NAPB
Published 2023“…Interestingly, the functions of the two proteins; VPS13B, a transmembrane protein involved in intracellular protein transport, and SNAP-beta involved in neurotransmitters release at the neuronal synaptic complexes, have been associated with Golgi-mediated vesicular trafficking. …”
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Genetic and heuristic algorithms for regrouping service sites. (c2000)
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Optimizing clopidogrel dose response
Published 2016“…Purpose Response to clopidogrel varies widely with nonresponse rates ranging from 4% to 30%. A reduced function of the gene variant of the CYP2C19 has been associated with lower drug metabolite levels, and hence diminished platelet inhibition. …”
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Single-Cell Transcriptome Analysis Highlights a Role for Neutrophils and Inflammatory Macrophages in the Pathogenesis of Severe COVID-19
Published 2020“…Further analyses revealed genes associated with the inflammatory response and chemotaxis of myeloid cells, phagocytes, and granulocytes, among the top activated functional categories in BAL from severe COVID-19-affected patients. …”
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A novel method for the detection and classification of multiple diseases using transfer learning-based deep learning techniques with improved performance
Published 2024“…Hence, in this study, deep learning algorithms, such as VGG16, EfficientNetB4, and ResNet, are utilized to diagnose various diseases, such as Alzheimer's, brain tumors, skin diseases, and lung diseases. …”
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Kernel-Ridge-Regression-Based Randomized Network for Brain Age Classification and Estimation
Published 2024“…Moreover, the proposed algorithm demonstrated excellent prediction accuracy with a mean absolute error (MAE) of <b>3.89</b> years, <b>3.64 </b>years, and <b>4.49</b> years for GM, WM, and CSF regions, confirming that changes in WM volume are significantly associated with normal brain aging. …”
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Economic Production Lot-Sizing For An Unreliable Machine Under Imperfect Age-Based Maintenance Policy
Published 2020“…Numerical results are provided to illustrate both the use of the algorithm in the study of the optimal cost function and the latter's sensitivity to different changes in cost factors. …”
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Anonymizing multimedia documents
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Blood-Based Proteomic Profiling Identifies Potential Biomarker Candidates and Pathogenic Pathways in Dementia
Published 2023“…We used a high-throughput proximity extension immunoassay to quantify 1090 proteins in 122 participants (22 with dementia, 64 with mild cognitive impairment (MCI), and 36 controls with normal cognitive function). Limma-based differential expression analysis reported the dysregulation of 61 proteins in the plasma of those with dementia compared with controls, and machine learning algorithms identified 17 stable diagnostic biomarkers that differentiated individuals with AUC = 0.98 ± 0.02. …”
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CFD Based Airfoil Shape Optimization for Aerodynamic Drag Reduction
Published 2012Get full text
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Single-Cell Transcriptome Analysis Revealed Heterogeneity and Identified Novel Therapeutic Targets for Breast Cancer Subtypes
Published 2023“…Differential expression and gene set enrichment analysis in TNBC revealed enrichment in the cycle and mitosis functional categories in FDPShigh, while ENO1high was associated with numerous functional categories, including cell cycle, glycolysis, and ATP metabolic processes. …”
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Improving the Resilience of Smart Distribution Networks against Cyber Attacks
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Regression testing web services-based applications
Published 2006“…Moreover, modifications handled by the algorithm are classified into three classes: (a) adding an operation, (b) deleting an operation, (c) fixing a condition or an action. …”
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