A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate by Geethakumari, Anupriya M

“…Further, mutational analysis revealed a requirement for both cleavage sites to be intact for increased cleavage rate. Importantly, the inclusion of an Mpro-binding, but non-inhibiting, NB2E3 nanobody at the N-terminal further increased the cleavage rate of the 2× cleavage sequence-containing Mpro biosensor. …”
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A clustering metaheuristic for large orienteering problems by Almiqdad Elzein (13141038)

“…The metaheuristic aims to dramatically improve the computation time of a given Orienteering Problem algorithm without a significant decrease in the solution quality of that algorithm, especially for large Orienteering Problems. …”

A GRASP Approach for Solving Large-Scale Electric Bus Scheduling Problems by Raka Jovanovic (17947838)

“…To be able to solve large problem instances corresponding to real-world applications of the model, a metaheuristic approach is investigated. …”

When Should a Brain MRI Be Performed in Children with New-Onset Seizures? Results of a Large Prospective Trial by Hourani, R.

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The Effect of Soy Isoflavones on Steroid Metabolism by Amanda C. Swart (18153814)

“…<h3>Objective</h3><p dir="ltr">This study is a post-hoc analysis of steroid hormones before and after administration of pharmacological doses of soy isoflavones in a large cohort of men and women from two independent studies. …”

The Effect of the Variation of the Modulus of Subgrade Reaction on the Design of Large Shallow Foundations by Al Kaaby Al Zoaby, Hassan

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Shear Strength Behaviors of Tire Shred-Dune Sand Admixtures by Elmootassem, Ruba A.

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Assessment of Brain Function After 240 Days Confinement Using Functional Near Infrared Spectroscopy by Yahya, Fares

“…The power spectral density shows a significant increase with time-in-mission across all participants in most of the frontal area. …”
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Breaking the barriers towards large-scale microalgae-based bio-hydrogen production by Isra Koko (22631396)

The ortholog of human ssDNA-binding protein SSBP3 influences neurodevelopment and autism-like behaviors in <i>Drosophila melanogaster</i> by Safa Salim (9186786)

“…One such gene is the single-stranded DNA-binding protein 3 (<i>SSBP3</i>) and its Drosophila melanogaster ortholog is called sequence-specific single-stranded DNA-binding protein (<i>Ssdp</i>). …”

The emergence of new SARS-CoV-2 variant (Omicron) and increasing calls for COVID-19 vaccine boosters-The debate continues by Naushad Ahmad Khan (6406973)

“…The Delta variant was reported to have increased transmissibility, higher viral load [4] and high rates of reinfection [5]. …”

Parallel multi-voltage power minimization in VLSI circuits. (c2013) by Younes, Rabih Halim

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Operation optimization of propane pre-cooled mixed refrigerant LNG Process: A novel integration of knowledge-based and constrained Bayesian optimization approaches by Roba Shady (22048043)

“…In addition, the optimized SEC in this study is 14.5 % to 38.6 % lower than those reported in the literature. At large-scale LNG production (10,000 tons per day), the reduction in the SEC is translated into an 18 MW decrease in compression power, saving approximately 4.7 million $ per year for each C3MR train. …”

The synthetic cathinones MDPHP and MDPV: Comparison of the acute effects in mice, in silico ADMET profiles and clinical reports by Marta, Bassi

“…Our results substantiated that MDPHP and MDPV similarly affect sensorimotor and behavioural responses in mice, importantly increased locomotion and induced aggressive behaviour, and, at higher dosage, increased heart rate and blood pressure. …”
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Shear Strength Behavior of Tire Shred-Dune Sand Admixtures by Ahmad, Abrar

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COVID-19 biomarkers for severity mapped to polycystic ovary syndrome by Abu Saleh Md Moin (6189512)

“…However, it is observed that in metabolic conditions such as polycystic ovary syndrome expressed proteins differ compared to control women [2] and PCOS patients have increased platelet aggregation and decreased plasma fibrinolytic activity, resulting in a prothrombotic propensity [3, 4], with elevated coagulation markers [5]. …”

Antibody‐based methods for the measurement of α‐synuclein concentration in human cerebrospinal fluid – method comparison and round robin study by Brit Mollenhauer (482499)

“…A large body of literature suggests that these disorders are characterized by reduced concentrations of α‐synuclein in cerebrospinal fluid (CSF), with overlapping concentrations compared to healthy controls and variability across studies. …”

Enhanced optical properties of <i>β</i>-Ga₂O₃-_<em>x</em>S_<em>x</em>S: A DFT study by G.B. Eshonqulov (22927297)

“…<p dir="ltr"><a href="https://www.sciencedirect.com/topics/materials-science/gallium" target="_blank">Gallium</a> <a href="https://www.sciencedirect.com/topics/materials-science/oxide-compound" target="_blank">oxide</a> (GaO) is a promising material for ultraviolet optoelectronic applications due to its desirable properties, such as a large band gap, decent charge mobility, and high breakdown electrical characteristics. …”

Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis... by Marissa B Reitsma (8674341)

“…Substantial progress in reducing the prevalence of smoking tobacco use has been observed in countries from all regions and at all stages of development, but a large implementation gap remains for tobacco control. …”

Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss by Meritxell Espino Guarch (18810097)

“…<p dir="ltr">Age-related hearing loss (ARHL) is the most common sensory deficit in the elderly. The disease has a multifactorial etiology with both environmental and genetic factors involved being largely unknown. …”