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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
Published 2025“…Further, mutational analysis revealed a requirement for both cleavage sites to be intact for increased cleavage rate. Importantly, the inclusion of an Mpro-binding, but non-inhibiting, NB2E3 nanobody at the N-terminal further increased the cleavage rate of the 2× cleavage sequence-containing Mpro biosensor. …”
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Preoperative Bevacizumab Does Not Significantly Increase Postoperative Complication Rates in Patients Undergoing Hepatic Surgery for Colorectal Cancer Liver Metastases
Published 2008“…Purpose Although bevacizumab (BV) increases survival rates when used with chemotherapy (CTX) in patients who have metastatic colorectal cancer (CRC), an increase in wound complications has been observed in patients who undergo surgery while receiving BV. …”
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Exploring students’ understanding of the second derivative within the context of a differential equations course
Published 2025“…The teaching of this course emphasizes a qualitative approach and therefore a solid understanding of the first and second derivatives is critical to determine the increase/decrease of solutions as well as their rate of increase/decrease. …”
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Intelligent Rapidly-Exploring Random Tree Star Algorithm
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Effect of heating rate on the pyrolysis of camel manure
Published 2022“…The results indicated that the increase in heating rates increased the starting and ending temperatures (decomposition) of manure components. …”
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On the effects of user ratings on the profitability of cloud services
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Second-law-based performance evaluation of cooling towers and evaporative heat exchangers
Published 2020“…For the different input variables investigated, efficiencies were, almost always, seen to increase or decrease monotonically. We notice that an increase in the inlet wet bulb temperature invariably increases the second-law efficiency of all the heat exchangers. …”
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The thioredoxin homolog YbbN functions as a chaperone rather than as an oxidoreductase
Published 2008“…It increases 4-fold the rate of protein renaturation in vitro by the DnaK chaperone machine, suggesting that it cooperates with DnaK for the optimal expression of several cytoplasmic proteins.…”
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Effect of the stretch rate during uniaxial testing on the mechanical properties of prolene
Published 2017“…Statistically significant findings suggest an increasing trend for Prolene® stiffness vs. stretch rate (R2 = 0.9679; two-tailed p value = 0.0025) where the stiffness increases 26.2% when increasing the displacement rate from 1 to 500 mm/min. …”
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An optimal formulation for test scheduling network-on-chip using multiple clock rates
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Monitoring the variation of soil quality with sewage sludge application rates in absence of rhizosphere effect
Published 2020“…The dose-dependent improvement of organic matter content was the most significant event that reflected sludge application rates, and consequently influenced other soil properties. …”
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Neither Neoadjuvant nor Adjuvant Therapy Increases Survival After Biliary Tract Cancer Resection with Wide Negative Margins
Published 2012“…One hundred fifty-seven patients underwent resection for primary GBC (n = 63) and CC (n = 94). Fisher’s exact test, Student’s t test, the log-rank test, and a Cox proportional hazard model determined significant differences. …”
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