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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
Published 2025“…Further, mutational analysis revealed a requirement for both cleavage sites to be intact for increased cleavage rate. Importantly, the inclusion of an Mpro-binding, but non-inhibiting, NB2E3 nanobody at the N-terminal further increased the cleavage rate of the 2× cleavage sequence-containing Mpro biosensor. …”
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Parallel multi-voltage power minimization in VLSI circuits. (c2013)
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On the effects of user ratings on the profitability of cloud services
Published 2017“…The surprising point is that providers having low ratings do not get much benefit from increasing their average ratings, meanwhile, they can perform well when they lower the service price.…”
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Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic anal...
Published 2020“…Independent estimates of HIV-specific mortality generated by an epidemiological analysis of HIV prevalence surveys and antenatal clinic serosurveillance and other sources were incorporated into the estimates in countries with large epidemics. Annual and single-year age estimates of net migration and population for each country and territory were generated using a Bayesian hierarchical cohort component model that analysed estimated age-specific fertility and mortality rates along with 1250 censuses and 747 population registry years. …”
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Operation optimization of propane pre-cooled mixed refrigerant LNG Process: A novel integration of knowledge-based and constrained Bayesian optimization approaches
Published 2024“…In addition, the optimized SEC in this study is 14.5 % to 38.6 % lower than those reported in the literature. At large-scale LNG production (10,000 tons per day), the reduction in the SEC is translated into an 18 MW decrease in compression power, saving approximately 4.7 million $ per year for each C3MR train. …”
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Traffic fatality trends in four continents based micro level data for three decades
Published 2015“…The analysis is based on gathered traffic death frequencies and rates for over three decades considering 176 countries within the four continents. …”
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Effect of the stretch rate during uniaxial testing on the mechanical properties of prolene
Published 2017“…Statistically significant findings suggest an increasing trend for Prolene® stiffness vs. stretch rate (R2 = 0.9679; two-tailed p value = 0.0025) where the stiffness increases 26.2% when increasing the displacement rate from 1 to 500 mm/min. …”
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Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burd...
Published 2021“…</p><p><br></p><h3>Methods</h3><p dir="ltr">We completed all-cause mortality and cause-specific mortality analyses from 204 countries and territories for detailed age groups separately, with aggregated mortality probabilities per 1000 livebirths computed for neonatal mortality rate (NMR) and under-5 mortality rate (U5MR). …”
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The Association of Hypertension with Increased Mortality Rate During the COVID-19 Pandemic: An Update with Meta-analysis
Published 2023“…Meta-regression analysis results also showed a statistically significant association between hypertension and COVID-19 mortality.</p><h3>Conclusion</h3><p dir="ltr">This systematic review and meta-analysis suggest that hypertension may not be the only risk factor associated with the increased mortality rate during the COVID-19 pandemic. …”
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Repeat hepatectomy for recurrent colorectal liver metastases is associated with a high survival rate
Published 2011“…The post-operative morbidity and mortality rates were 12% and 0%, respectively. After a median follow-up of 33 months from a repeat hepatectomy, 5-year overall and progression-free survival rates were 73% and 22%, respectively. …”
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Monitoring the variation of soil quality with sewage sludge application rates in absence of rhizosphere effect
Published 2020“…Accordingly, soil structural stability increased by 13.3%, 28.8% and 59.4% for treatments SS-40, SS-80 and SS-120 respectively as compared to unamended control. …”
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Effect of structural remodeling (retraction and recoil) of the pipeline embolization device on aneurysm occlusion rate
Published 2014“…The aneurysm occlusion rate, however, is lowered by overelongation of the Pipeline Embolization Device.…”
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Two-surgeon technique of parenchymal transection contributes to reduced transfusion rate in patients undergoing major hepatectomy
Published 2010“…Liver resection has been used increasingly in the last 20 years, and mortality rates associated with the procedure are less than 5% at high-volume centers.1, 2 and 3 The safety of liver resection is in part the result of the development of techniques aimed at reducing blood loss. …”
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Preoperative Bevacizumab Does Not Significantly Increase Postoperative Complication Rates in Patients Undergoing Hepatic Surgery for Colorectal Cancer Liver Metastases
Published 2008“…Purpose Although bevacizumab (BV) increases survival rates when used with chemotherapy (CTX) in patients who have metastatic colorectal cancer (CRC), an increase in wound complications has been observed in patients who undergo surgery while receiving BV. …”
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Comparison of quit rates among exclusive cigarette smokers at Tobacco Control Center in Qatar: telephone versus face-to-face consultation
Published 2025“…The objective of this study was to (1) determine if telephone care increases smoking quit rate compared to face-to-face intervention and (2) investigate factors associated with successful smoking cessation.…”
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Evaluation of Workability and Structuration Rate of Locally Developed 3D Printing Concrete Using Conventional Methods
Published 2022“…Higher a/b ratios resulted in increased structuration rate, buildability, and compressive strength of cast specimens. …”
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A clustering metaheuristic for large orienteering problems
Published 2022“…The metaheuristic aims to dramatically improve the computation time of a given Orienteering Problem algorithm without a significant decrease in the solution quality of that algorithm, especially for large Orienteering Problems. …”