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Increased Levels of Circulating and Tumor-Infiltrating Granulocytic Myeloid Cells in Colorectal Cancer Patients
Published 2016“…<p dir="ltr">Increased levels of myeloid cells, especially myeloid-derived suppressor cells (MDSCs), have been reported to correlate with bad prognosis and reduced survival in cancer patients. …”
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Increased levels of CSF total but not oligomeric or phosphorylated forms of alpha-synuclein in patients diagnosed with probable Alzheimer’s disease
Published 2017“…</p><h2>Other Information</h2><p dir="ltr">Published in: Scientific Reports<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1038/srep40263" target="_blank">https://dx.doi.org/10.1038/srep40263</a></p>…”
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Parallel multi-voltage power minimization in VLSI circuits. (c2013)
Published 2013Get full text
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MRP4
Published 2011“…Application of ISO (1nM) induced a similar increase in cAMP level in WT and MRP4 KO mice (YFP/CFP: 4.4 ± 0.15 in WT vs 4.1 ± 0.44 in KO cells), whereas cAMP signal was greater in MRP4 KO compared to WT mice after PDE inhibition by IBMX (ISO 1nM + IBMX 300µM: 8.1 ± 0.6 in WT vs 11.8 ± 0.62 in KO cells; p<0.01). …”
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Cardiac phosphodiesterases are differentially increased in diabetic cardiomyopathy
Published 2021“…Moreover, we noted an early and specific upregulation of cardiac PDE1A, PDE2A, PDE4B, PDE4D and PDE5A expression at week 4, followed by increases in PDE3A levels in diabetic hearts at week 8. …”
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Peripheral inflammatory and metabolic markers as potential biomarkers in treatment-resistant schizophrenia: Insights from a Qatari Cohort
Published 2024“…The NTRS group also showed higher HbA1c levels. Variations in inflammatory markers were noted, with the NTRS group exhibiting a higher platelet/lymphocyte ratio (PLR). …”
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Operation optimization of propane pre-cooled mixed refrigerant LNG Process: A novel integration of knowledge-based and constrained Bayesian optimization approaches
Published 2024“…In addition, the optimized SEC in this study is 14.5 % to 38.6 % lower than those reported in the literature. At large-scale LNG production (10,000 tons per day), the reduction in the SEC is translated into an 18 MW decrease in compression power, saving approximately 4.7 million $ per year for each C3MR train. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…In aged HSA-mUCP1 mice, urinary MG-derived AGEs/FL ratio was decreased ca. 60% whereas there was no change in CML/FL ratio – a marker of oxidative damage. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…In aged HSA-mUCP1 mice, urinary MG-derived AGEs/FL ratio was decreased ca. 60% whereas there was no change in CML/FL ratio – a marker of oxidative damage. …”
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Cyclosporine lymphocyte maximum level
Published 2005“…Patients with normal graft function exhibited significantly lower LC (0.001292 ± 696 x 109/L) and serum creatinine levels (88.4 ± 35 µmol/L) when compared with rejecting patients (0.001717 ± 364 x 109/L, 132.6 ± 8.8 µmol/L) and those with nephrotoxicity (0.001884 ± 582 x 109/L, 123.7 ± 8.8 µmol/L) (P < 0.03, P < 0.001). …”
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Potential of horizontal louvers in increased energy savings in a commercial building in Dubai
Published 2018“…The artificial lighting in the cabin is linked to the dimmer sensors to a configuration that the lights will dim to 0.4% its original power if the lux level in the room is more than 500 Lux. …”
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Urinary Metabolomic Markers of Protein Glycation, Oxidation, and Nitration in Early-Stage Decline in Metabolic, Vascular, and Renal Health
Published 2019“…Urinary analyte changes were as follows: impaired metabolic health—increased N<em>ε</em>-carboxymethyl-lysine, glucosepane, glutamic semialdehyde, and pyrraline; impaired vascular health—increased glucosepane; and impaired renal health—increased BCAAs and decreased N<em>ε</em>-(<em>γ</em>-glutamyl)lysine. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Inositol 1,4,5-Trisphosphate Receptors in Hypertension
Published 2018“…Evidence supports a role for vascular aging in the development of hypertension involving an impairment in endothelial function together with an alteration in vascular smooth muscle cells (VSMCs) calcium homeostasis leading to increased myogenic tone. Changes in free intracellular calcium levels ([Ca<sup>2+</sup>]<sub><em>i</em></sub>) are mediated either by the influx of Ca<sup>2+</sup> from the extracellular space or release of Ca<sup>2+</sup> from intracellular stores, mainly the sarcoplasmic reticulum (SR). …”