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A clustering metaheuristic for large orienteering problems
Published 2022“…The metaheuristic aims to dramatically improve the computation time of a given Orienteering Problem algorithm without a significant decrease in the solution quality of that algorithm, especially for large Orienteering Problems. …”
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Increased Levels of Circulating and Tumor-Infiltrating Granulocytic Myeloid Cells in Colorectal Cancer Patients
Published 2016“…<p dir="ltr">Increased levels of myeloid cells, especially myeloid-derived suppressor cells (MDSCs), have been reported to correlate with bad prognosis and reduced survival in cancer patients. …”
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Parallel multi-voltage power minimization in VLSI circuits. (c2013)
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Increased levels of CSF total but not oligomeric or phosphorylated forms of alpha-synuclein in patients diagnosed with probable Alzheimer’s disease
Published 2017“…</p><h2>Other Information</h2><p dir="ltr">Published in: Scientific Reports<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1038/srep40263" target="_blank">https://dx.doi.org/10.1038/srep40263</a></p>…”
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MRP4
Published 2011“…Application of ISO (1nM) induced a similar increase in cAMP level in WT and MRP4 KO mice (YFP/CFP: 4.4 ± 0.15 in WT vs 4.1 ± 0.44 in KO cells), whereas cAMP signal was greater in MRP4 KO compared to WT mice after PDE inhibition by IBMX (ISO 1nM + IBMX 300µM: 8.1 ± 0.6 in WT vs 11.8 ± 0.62 in KO cells; p<0.01). …”
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Cardiac phosphodiesterases are differentially increased in diabetic cardiomyopathy
Published 2021“…Moreover, we noted an early and specific upregulation of cardiac PDE1A, PDE2A, PDE4B, PDE4D and PDE5A expression at week 4, followed by increases in PDE3A levels in diabetic hearts at week 8. …”
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A GRASP Approach for Solving Large-Scale Electric Bus Scheduling Problems
Published 2021“…The analysis focuses on the relation between EB ranges (battery capacity) and required charging rates (in kW) on the size of the fleet needed to cover a public transport timetable. The results of the conducted computational experiments indicate that an increase in infrastructure investment through high speed chargers can significantly decrease the size of the necessary fleets. …”
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COVID-19 biomarkers for severity mapped to polycystic ovary syndrome
Published 2020“…<p dir="ltr">Large scale multi-omics analysis has identified significant differences in the biomarkers between COVID-19 disease and control subjects [1]. …”
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Cyclosporine lymphocyte maximum level
Published 2005“…Patients with normal graft function exhibited significantly lower LC (0.001292 ± 696 x 109/L) and serum creatinine levels (88.4 ± 35 µmol/L) when compared with rejecting patients (0.001717 ± 364 x 109/L, 132.6 ± 8.8 µmol/L) and those with nephrotoxicity (0.001884 ± 582 x 109/L, 123.7 ± 8.8 µmol/L) (P < 0.03, P < 0.001). …”
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Potential of horizontal louvers in increased energy savings in a commercial building in Dubai
Published 2018“…The artificial lighting in the cabin is linked to the dimmer sensors to a configuration that the lights will dim to 0.4% its original power if the lux level in the room is more than 500 Lux. …”
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Inositol 1,4,5-Trisphosphate Receptors in Hypertension
Published 2018“…Evidence supports a role for vascular aging in the development of hypertension involving an impairment in endothelial function together with an alteration in vascular smooth muscle cells (VSMCs) calcium homeostasis leading to increased myogenic tone. Changes in free intracellular calcium levels ([Ca<sup>2+</sup>]<sub><em>i</em></sub>) are mediated either by the influx of Ca<sup>2+</sup> from the extracellular space or release of Ca<sup>2+</sup> from intracellular stores, mainly the sarcoplasmic reticulum (SR). …”
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