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Methylation at global LINE-1 repeats in human blood are affected by gender but not by age or natural hormone cycles
Published 2011“…In vitro results largely confirmed these findings, as neither estrogen nor dihydrotestosterone affected LINE-1 or Alu methylation in Hek293T, HUVEC, or MDA-kb2 cell lines. …”
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A clustering metaheuristic for large orienteering problems
Published 2022“…The metaheuristic aims to dramatically improve the computation time of a given Orienteering Problem algorithm without a significant decrease in the solution quality of that algorithm, especially for large Orienteering Problems. …”
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The chemotherapeutic effect of β-2-himachalen-6-ol in chemically induced skin tumorigenesis
Published 2018“…Only Cisplatin treatment caused a significant decrease in body weight and increase in serum ALT. In conclusion, β-2-himachalen-6-ol induced significant tumor shrinkage, an effect partly mediated via promoting apoptosis through inhibition of the MAPK/ERK and PI3K/AKT pathways, with no significant toxicity to laboratory mice.…”
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Performance of Olive Waste Ash Concrete Exposed to Thermal Cycling
Published 2010“…The OWA concrete was found more resistant to thermal cycling compared to plain concrete. Additionally, the resistance of OWA concrete to thermal cycling increased with increasing the OWA content. …”
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THE USE OF AN OPEN CYCLE ABSORPTION SYSTEM IN AUTOMOBILES AS AN ALTERNATIVE TO CFCS
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β-2-himachalen-6-ol protects against skin cancer development in vitro and in vivo
Published 2017“…Flow cytometry analysis revealed that treatment with 10 μg/ml HC significantly increased the number of cells undergoing late apoptosis (28%), while 25 μg/ml caused a larger cell shift towards late apoptosis (46.6%) and necrosis (39%). …”
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Dietary Curcumin Nanoparticles Improve Growth Performance, Oxidative Status and Immune Response of European Seabass (<i>Dicentrarchus Labrax</i>)
Published 2024“…Fish fed with CURNPS at various levels exhibited remarkable increase in digestive enzymes (amylase and lipase), immune markers (immunoglobulin G (IgG), lysozyme and phagocytic indices), and antioxidant enzymes (superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx)). A noticeable decrease (P<0.05) in malondialdehyde (MDA) and considerable upregulation of hepatic insulin-like growth factor 1 (IGF1) and interleukin-1beta (IL-1β) mRNA levels were found in CURNPs-supplemented fish in a dose-dependent manner. …”
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Parallel multi-voltage power minimization in VLSI circuits. (c2013)
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Off-design performance analysis of combined CSP power and direct oxy-combustion supercritical carbon dioxide cycles
Published 2021“…On the other hand, the increase of the TIT improves the cycle efficiency (by 8.6%) but also increases the consumed fuel by (57%).…”
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Off-design performance analysis of combined CSP power and direct oxy-combustion supercritical carbon dioxide cycles
Published 2021“…On the other hand, the increase of the TIT improves the cycle efficiency (by 8.6%) but also increases the consumed fuel by (57%).…”
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Comparative life cycle assessment of sustainable energy carriers including production, storage, overseas transport and utilization
Published 2021“…<p dir="ltr">Countries are under increasing pressure to reduce greenhouse gas emissions as an act upon the Paris Agreement. …”
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Antitumor activity of β-2-himachalen-6-ol in colon cancer is mediated through its inhibition of the PI3K and MAPK pathways
Published 2017“…Chemical analysis of DCOE led to the isolation of β-2-himachalen-6-ol (HC) which exhibited potent anticancer activity against colon, breast, brain and skin cancer cells. …”
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The anticancer effect of β-2 himachalen-6-ol from Lebanese wild carrot on human acute myeloid leukemia cells. (c2016)
Published 2016“…There was no sign of cell cycle arrest. Co-incubation of AML cells with β-2-himachalen-6-ol and a MEK1/2 inhibitor (U0126) revealed an additive effect in Mono-Mac-1 and U937; the effect was mild in HL60. …”
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Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018)
Published 2018“…Both cell lines showed increased sensitivity at longer incubation periods of [HuArgI (Co)-PEG5000] treatment with IC50 values in the pM range, a result attributable to the arginine auxotrophy expressed in those two cell lines. …”
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Effects of vitamin E derivatives on the proliferation of KG-1 leukemic cells in vitro
Published 2017“…XTT cell viability assay, which detects the presence of metabolically active cells, was used to assess cell proliferation. A decrease in proliferation of KG-1 cells was observed upon treatment with both forms of vitamin E derivatives; however, β-T3 was more potent than γ-T3 in promoting cell death with lower IC50 values. …”
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