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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…The optimal management of PDA in these infants is unsettled; however, medical treatment with cyclooxygenases (COX) inhibitors such as ibuprofen or indomethacin is the current practice in most neonatal intensive care units (NICU). Most studies show equal efficacy of both drugs but with a better side effect profile with ibuprofen treatment. …”
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Evidence and gaps in clinical outcomes of novel pharmacologic therapies for sickle cell disease: A systematic literature review highlighting insights from clinical trials and real-...
Published 2025“…The high discontinuation rate and results of the STAND trial led to a significant decrease in the use of crizanlizumab. The HOPE trial demonstrated a 51 % improvement in hemoglobin response and a reduction in hemolytic markers in patients treated with voxelotor. …”
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Percutaneous coronary intervention can be safely performed with left ventricular thrombus without increasing stroke risk: A 5-year retrospective review using real-world data
Published 2023“…Most of the patients were Asian (67%), male (96%), with a mean age of 56 years. …”
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Exendin-4 promotes GSIS without increasing β-cell number through upregulation of glucose-sensing apparatus and mitochondrial oxidative phosphorylation machinery genes in hPSC-deriv...
Published 2023“…Interestingly, addition of Exendin-4 (50 nM) during the last 3 days of the differentiation significantly enhanced GSIS associated with increased expression of glucose-sensing apparatus genes (Glut2, G6P2C, GCK) and genes encoding mitochondrial oxidative phosphorylation machinery.…”
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STARD 13 in prostate cancer. (c2018)
Published 2018“…Knocking down StarD13 by siRNA led to an increase in cell proliferation and adhesion yet a decrease in cell motility and cell speed in prostate cancer. …”
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The relationship between Determinants of Risk Governance assurance and efficacy of the Public projects in the Government of Dubai from the perspective of Internal Audit Function
Published 2018“…The success of these public initiatives may create the course for the government to decrease its reliance on other sectors. However, not all of these projects are completed on time and adhering to the predetermined budget. …”
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Urban Geometry: The Effect of Height Diversity and Buildings Configuration on Thermal Performance and Cooling Load at Urban Scale. A Case Study in Dubai / UAE
Published 2018“…Therefore, designing the urban block with a significant diversity in building heights, or gradual height variation will have the potential of a shading effect and wind speed increase to enhance the thermal performance of the urban block. …”
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Trade Flow and Nation Brand Distance: A Structural Gravity Model Approach
Published 2021“…The results on the impact of NBD on FTA and trade flows provides some interesting insights as the there is a negative and significant moderation impact of NBD on the relationship between FTA and both export and import volume which suggest that a decrease of NBD will increase the effect of FTA on trade flow. …”
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Estimation of Virtual Trust on Driverless Cars using Type-1 Fuzzy logic
Published 2024“…These cars utilize cutting-edge technology to efficiently address human mobility needs. Using the most advanced technological elements, this is a significant advancement in the automobile manufacturing sector. …”
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Visitors off the trail: Impacts on the dominant plant, bryophyte and lichen species in alpine heath vegetation in sub-arctic Sweden
Published 2021“…The results showed that proximity to the trail did not cause a decrease in the majority of dominant species, with none of the eight most dominant vascular plants showing any significant effects of proximity to the trail. …”
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Pharmacological evaluation of aqueous extract of Althaea officinalis flower grown in Lebanon
Published 2011“…Increasing the dose to 500 mg/kg body weight caused a significant decrease in stool water content. …”
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Efficacy of Lebanese Cannabis Oil Extract in the Treatment of Folic Acid-Induced Renal Fibrosis in Rats
Published 2023“…Treatment with 20mg/Kg Cannabis oil caused a significant increase in body weight compared to the Folic acid treated group. …”
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Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells
Published 2021“…Western blot analysis showed significant decrease in stem cell markers SOX-2 and Oct-4, and tumorigenic protein HMGA1, whereas it showed significant increase in apoptotic markers cleaved PARP and cleaved caspase-3. …”
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Orthodontic camouflage versus orthodontic-orthognathic surgical treatment in borderline class III malocclusion: a systematic review
Published 2022“…Regarding the vertical jaw relation, one study reported a significant decrease in mandibular plane inclination in OC and a significant increase in OOS. …”
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Formation of Trihalomethanes during Seawater Chlorination
Published 2010“…Chlorination of seawater has shown significant increase in total THMs (TTHMs) and in bromoform concentrations. …”
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Assessment of Brain Function After 240 Days Confinement Using Functional Near Infrared Spectroscopy
Published 2024“…The FCN shows a significant decrease in most of the right frontal areas. …”
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