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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…In conjunction with these data, whole-cell electrophysiological studies revealed that this concentration had maximum effect on membrane potentials, conductance and currents. Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. …”
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The Potential Role of Daucus carota Aqueous and Methanolic Extracts on Inflammation and Gastric Ulcers in Rats
Published 2009“…None of the extracts showed significant antibacterial activity. DCAE intake (250 mg/kg body weight) for one month period did not show adverse effects on lipemia, glycemia, hepatic and liver function except for a slight decrease in HDL cholesterol (p<0.05). …”
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Global, regional and national burden of bladder cancer and its attributable risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of...
Published 2021“…Bladder cancer accounted for 4.39 million (4.09 to 4.70) DALYs in 2019, and the age-standardised DALY rate decreased significantly by 18.6% (11.2 to 24.3) during the period 1990–2019. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Kefir's anti‑cancer potential was tested on CRC cell lines, Caco‑2 and HT‑29, through cytotoxicity, proliferation, and apoptotic assays. …”
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Effect of the stretch rate during uniaxial testing on the mechanical properties of prolene
Published 2017“…No statistically significant dependence of peak load on stretch rate was found. …”
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Pharmacist Role in Hypertension Management in the Community Setting: Questionnaire Development, Validation, and Application
Published 2023“…Pharmacists can play a substantial role in decreasing the burden of the disease.</p><h3>Purpose</h3><p dir="ltr">The primary aim of this study was to develop and validate a scale assessing the pharmacist role in hypertension management in the community pharmacy setting. …”
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A comprehensive design and rating study of evaporative coolers and condensers. Part I. Performance evaluation
Published 2020“…It is demonstrated that thermal effectiveness of the evaporative heat exchangers degrades significantly with time indicating that, for a low risk level (pZ0.01), there is about 66.7% decrease in effectiveness for the given fouling model. …”
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Wave-packet dynamics in monolayer graphene with periodic scattering potentials
Published 2025“…For example, depending on the height and size of the incident wave packet, the transmission probability can decrease by more than 30%. The alteration of the polarity of the potential barriers also contributes to the transmission probabilities of the wave packets in graphene. …”
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Suppression of Unstable Flow by Using Rough Surfaces at Small Mass Flow Rates in a Radial Diffuser
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Two-surgeon technique of parenchymal transection contributes to reduced transfusion rate in patients undergoing major hepatectomy
Published 2010“…The decrease in transfusion rate associated with the use of the 2-surgeon technique emphasizes the important role of the hepatobiliary surgeon in determining outcomes after liver resection. …”
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Unpacking the asymmetric impact of exchange rate volatility on trade flows: A study of selected developed and developing Asian economies
Published 2023“…The non-linear models yielded more significant findings, while the linear models did not indicate any significant effects of exchange rate volatility on trade flows. …”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …”
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Role of family in supporting children with mental disorders in Qatar
Published 2023“…Age has no statistically significant effect on the role of family members in supporting people with mental disorders.…”
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Heart Rate Variability Analysis Reveals a Non-monotonic Relationship between Humanin Concentration and Cardiac Autonomic Regulation
Published 2022“…Humanin (HN), a mitochondrial-derived peptide, plays an important role in lowering OS. Sympathovagal balance was assessed in 124 healthy participants through heart rate variability (HRV) analysis and compared across changes in HN concentrations divided into quintiles, with values of HN ranging from 64.6 to 343.2 pg/mL. …”
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