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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…The expression of certain genes involved in proliferation and apoptosis was measured using reverse transcriptase‑polymerase chain reaction (RT‑PCR) and western blotting. …”
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Evaluation of The Factors Affecting Microplastics and Nanoparticles in Plastic Water Supply Pipes
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Reversal of memory and neuropsychiatric symptoms and reduced tau pathology by selenium in 3xTg-AD mice
Published 2018“…Selenium significantly decreased the number of aggregated tau-positive neurons and astrogliosis, without globally affecting amyloid plaques, in the hippocampus of 3xTg-AD mice. …”
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Inland Treatment of the Brine Generated from Reverse Osmosis Advanced Membrane Wastewater Treatment Plant Using Epuvalisation System
Published 2013“…The reverse osmosis (RO) brine generated from the Al-Quds University wastewater treatment plant was treated using an epuvalisation system. …”
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Postprandial lipaemia 10 and 34 hours after playing football: Does playing frequency affect the response?
Published 2019“…For the 3FOOT, there was a non significant decrease in postprandial TG AUC (-2.7%; p = 0.73; 95%CI = -2.0 to 1.5; ES = 0.05) and iAUC (-17.5%; p = 0.41; 95%ci = -2.5 to 1.1; ES = 0.31) from 10 to 34 hrs, respectively. …”
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Methylation at global LINE-1 repeats in human blood are affected by gender but not by age or natural hormone cycles
Published 2011“…In vitro results largely confirmed these findings, as neither estrogen nor dihydrotestosterone affected LINE-1 or Alu methylation in Hek293T, HUVEC, or MDA-kb2 cell lines. …”
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Multilayer Reversible Data Hiding Based on the Difference Expansion Method Using Multilevel Thresholding of Host Images Based on the Slime Mould Algorithm
Published 2022“…This is because placing data in an image can cause permanent distortion after data mining. Therefore, a reversible data hiding (RDH) technique is required. …”
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The impact of maternal care on child development
Published 2019“…Studying heterogeneous effects reveals a differential impact by child's age. An increase of 6.5 h per week in the time 2-year-olds spend with their mothers significantly improves their non-cognitive skills.…”
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The Impact of Employee Engagement on Turnover Intention and Burnout
Published 2021“…Employee engagement has been the center of attention for a long period because of the significant positive impact that it exerts on work-related outcomes of employees. …”
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Unpacking the asymmetric impact of exchange rate volatility on trade flows: A study of selected developed and developing Asian economies
Published 2023“…The results of the study suggest that in the case of Pakistan, both the linear and non-linear models indicate that increased exchange rate volatility adversely affects exports and imports, while decreased volatility enhances both. …”
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The Impact of the 2019 Lebanese Multidimensional Crisis on Young Adults’ Political Attitudes and Behavior
Published 2022“…Findings show that the 2019 multidimensional crisis had a significant negative impact on young adults’ political attitudes and behavior, affecting their affiliations, political interest, and trust. …”
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3D Concrete Printing Sustainability: A Comparative Life Cycle Assessment of Four Construction Method Scenarios
Published 2020“…Moreover, the use of an alternative concrete mixture in 3DCP showed a further decrease in the GWP, AP, EP, and FFD impact. Ultimately, the findings in this paper support the advantages of 3DCP technology and recommend the investigation of the development of (i) sustainable printable concrete materials and (ii) novel reinforcement techniques that are suitable for 3DCP rather than adopting conventional reinforcement techniques.…”
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The Impact of a Computerized Potassium Alert on Adverse Drug Events and Pharmacists' Interventions
Published 2010“…Conclusions: Implementation of a computerized pharmacy alert resulted in a statistically significant decrease in adverse drug events related to hyperkalemia in our institution. …”
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Impact of the positive pressure valve on vascular access device occlusions and bloodstream infections
Published 2009“…These types of devices have been shown to significantly decrease VAD occlusion rates by 8.2%, when compared to a standard connector device (Jacobs et al., 2004). …”
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