Immunoprofile of childhood diabetes by Meritxell Espino-Guarch (15430868)

“…</p> <p>Methods: Here we collected transcriptomic and metabolomic data from 86 children under 17 years-old to identify the regulatory events that participate in IR development. A comparative analysis of the transcriptome of the two major subtypes of CD4+ T cells, regulatory-T cells (Treg) and conventional T cells (Tcon) was conducted and compared with the plasma metabolome of 14 Control, 19 Obese, 17 Pre-diab, 16 T2D, and 20 T1D cases. …”

Understanding the Mechanism of Diabetes Mellitus in LRBA-Deficient Patient by Iman Hawari (12561958)

“…Knocking down LRBA did not induce immediate cell death, but lead to a reduced glucose metabolism in β cell.</p><h3>Conclusion</h3><p dir="ltr">To report a novel nonsense mutation in <i>LRBA</i>. …”