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Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018)
Published 2018“…Both cell lines showed increased sensitivity at longer incubation periods of [HuArgI (Co)-PEG5000] treatment with IC50 values in the pM range, a result attributable to the arginine auxotrophy expressed in those two cell lines. …”
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masterThesis -
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Increasing efficiency of atriums in hot, arid zones
Published 2019“…Increasing the number of floors reduced the energy consumption by 5% per unit area. …”
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Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017)
Published 2017“…Sensitivity to arginine depletion using HuArgI (Co)-PEG5000 was evident in all of the tested PC cell lines with IC50 values in the pM range at 72 hours following treatment. …”
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masterThesis -
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Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1<sup>+</sup>/NKX6.1<sup>+</sup> progenitors
Published 2024“…Recent studies have also shown <i>RFX6</i> variants to be linked with type 2 diabetes. …”
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Elucidating the Probiotic Potential of <i>Lactobacillus</i> and <i>Bifidobacterium</i> Species in Modulating Glucose Metabolism and Inflammation in Gestational Diabetes Mellitus: A...
Published 2025“…Improvements in glucose metabolism were linked to short-chain fatty acids (SCFAs), activating G-protein coupled receptors (GPRs), boosting GLP1 secretion, and insulin release. Probiotic interventions also favorably modulated inflammatory markers (high-sensitivity C-reactive protein, interleukin-6 [IL-6], and tumor necrosis factor-α), likely through enhanced mucus production, SCFAs binding to GPR109, strengthening tight junctions, and concurrent release of IL-18 and IL-10. …”
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P-glycoprotein expression and function are increased in an animal model of amyotrophic lateral sclerosis
Published 2010“…Consistent with this, P-gp function was also increased by 1.5-fold and riluzole brain disposition was decreased by 1.7-fold in mSOD1 mice. …”
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Potential of horizontal louvers in increased energy savings in a commercial building in Dubai
Published 2018“…This dissertation investigates the use of horizontal louvers in increasing the energy efficiency of an office cabin in Dubai, facing south direction. …”
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Increase of satellite tobacco ringspot virus RNA initiated by inoculating circular RNA
Published 1995“…These results are consistent with models for the replication of the satellite RNA in which a circular form of the satellite RNA is a template for rolling circle transcription or is otherwise a replication intermediate or is readily converted to an intermediate. We also show that a circular form of a nonaccumulating satellite RNA mutant induced an increase in a satellite RNA that is endogenous to some tobacco ringspot virus virion preparations, as demonstrated previously for the linear form.…”
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Downregulation of Lymphoid enhancer‐binding factor 1 (<i>LEF‐1)</i> expression (by immunohistochemistry and/ flow cytometry) in chronic Lymphocytic Leukemia with atypical immunophe...
Published 2020“…</p><h3>Conclusion</h3><p dir="ltr">As downregulation of <i>LEF-1</i> expression is well correlated with atypical CLL, we suggest adding <i>LEF-1</i> to Matutes score as a beneficial marker to differentiate classic from atypical CLL <i>LEF-1</i> could also serve as a potential prognostic indicator for CLL clinical course.…”
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Increased Levels of Circulating and Tumor-Infiltrating Granulocytic Myeloid Cells in Colorectal Cancer Patients
Published 2016“…Interestingly, the expansion of peripheral GMCs correlated with higher stage and histological grade of cancer, thereby suggesting their role in cancer progression. Furthermore, an increase in CD33<sup>+</sup>CD11b<sup>+</sup>HLA-DR<sup>−</sup>CD14<sup>−</sup>CD15<sup>−</sup> immature myeloid cells was also observed in CRC tumor tissue. …”
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Increasing methylation of sperm rDNA and other repetitive elements in the aging male mammalian germline
Published 2020“…Similar to the tandemly repeated rDNA, methylation of human α‐satellite and interspersed LINE1 repeats, marmoset α‐satellite, bovine alpha‐ and testis satellite I, mouse minor and major satellite, and LINE1‐T repeats increases in the aging male germline, probably related to their sperm histone packaging. …”
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The Association of Hypertension with Increased Mortality Rate During the COVID-19 Pandemic: An Update with Meta-analysis
Published 2023“…Subgroup analyses indicated that patients with COVID-19 who have hypertension and male patients had slightly less risk of mortality than female patients [the percentage of men > 50%; OR 1.33: 95% CI (1.01, 1.76); the percentage of men ≤ 50%: OR 2.26; and 95% CI (1.15, 4.48)]. …”
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Studies on Natural Extracts as Inhibitors of Mild Steel Corrosion in 1M HC1 Solution
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doctoralThesis -
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Response of cauliflower (<i>Brassica oleracea</i> L.) to nitric oxide application under cadmium stress
Published 2022“…Although, toxic effect of Cd in the sand can overcome by the application of NO which not only increased plant growth and nutrients accumulation but also decreased the oxidative damage to the membranous bounded organelles and also Cd accumulation in various parts of the plants in all genotypes of B. oleracea. …”
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One Hundred Years After “Carcinoid”
Published 2008“…We observed a significant increase in the reported annual age-adjusted incidence of NETs from 1973 (1.09/100,000) to 2004 (5.25/100,000). …”
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