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Showing 1 - 20 results of 165 for search '(( 1 i decrease ) OR ((( _ we decrease ) OR ( _ e decrease ))))~', query time: 0.19s Refine Results
  1. 1
    Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle

    Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit, Masania

    Published 2023
    “…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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  2. 2
    Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle

    Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit, Masania

    Published 2023
    “…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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  3. 3
    Quality improvement can decrease blood delivery turnaround time: Evidence from a single tertiary-care academic medical center

    Quality improvement can decrease blood delivery turnaround time: Evidence from a single tertiary-care academic medical center by Hammad Y.A.

    Published 2018
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  4. 4
    Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2.

    Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2. by P, Sneha

    Published 2018
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  5. 5
    A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation causing breast cancer.

    A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation... by Thirumal Kumar, D

    Published 2019
    “…The molecular interaction study also revealed that the co-crystallized AKT1 inhibitor N-(4-(5-(3-acetamidophenyl)-2-(2-aminopyridin-3-yl)-3H-imidazo [4,5-b]pyridin-3-yl)benzyl)-3-fluorobenzamide (12j) exhibited a better interaction with native AKT1 compared with the E17K mutant AKT1 protein, whereas, Akti-1/2 exhibited the opposite effects, i.e., a better interaction with the E17K mutant AKT1 than the native AKT1. …”
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  6. 6
    Quantification of the growth suppression of HER2+ breast cancer colonies under the effect of trastuzumab and PD-1/PD-L1 inhibitor.

    Quantification of the growth suppression of HER2+ breast cancer colonies under the effect of trastuzumab and PD-1/PD-L1 inhibitor. by Padmanabhan, Regina

    Published 2022
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  7. 7
    The Interference of Notch1 target Hes1 affects cell growth, differentiation and invasiveness of glioblastoma stem cells through modulation of multiple oncogenic targets

    The Interference of Notch1 target Hes1 affects cell growth, differentiation and invasiveness of glioblastoma stem cells through modulation of multiple oncogenic targets by Cenciarelli, Carlo

    Published 2017
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  8. 8
    Drastic difference between hole and electron injection through the gradient shell of Cd: XSeyZn1- xS1- y quantum dots

    Drastic difference between hole and electron injection through the gradient shell of Cd: XSeyZn1- xS1- y quantum dots by Abdellah, Mohamed

    Published 2017
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  9. 9
    SIRT1 may play a crucial role in overload-induced hypertrophy of skeletal muscle

    SIRT1 may play a crucial role in overload-induced hypertrophy of skeletal muscle by Koltai, Erika

    Published 2017
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  10. 10
    Glycolytic overload-driven dysfunction of periodontal ligament fibroblasts in high glucose concentration, corrected by glyoxalase 1 inducer

    Glycolytic overload-driven dysfunction of periodontal ligament fibroblasts in high glucose concentration, corrected by glyoxalase 1 inducer by Ashour, Amal

    Published 2020
    “…Results In high glucose concentration cultures, there was a ca. twofold increase in cellular MG, cellular protein MG-H1 content and decreased attachment of PDLFs to collagen-I. …”
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  11. 11
    Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach

    Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach by P., Sneha

    Published 2017
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  12. 12
    Cry1Ac toxicity enhancement towards lepidopteran pest Ephestia kuehniella through its protection against excessive proteolysis

    Cry1Ac toxicity enhancement towards lepidopteran pest Ephestia kuehniella through its protection against excessive proteolysis by Elleuch, Jihen

    Published 2016
    “…The P20 presence slightly increased Cry1Ac inclusions solubility in E. kuehniella midgut conditions. …”
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  13. 13
    Elaeagnus angustifolia Plant Extract Inhibits Angiogenesis and Downgrades Cell Invasion of Human Oral Cancer Cells via Erk1/Erk2 Inactivation.

    Elaeagnus angustifolia Plant Extract Inhibits Angiogenesis and Downgrades Cell Invasion of Human Oral Cancer Cells via Erk1/Erk2 Inactivation. by Saleh, Alaaeldin I

    Published 2018
    “…These changes are accompanied by an upregulation of E-cadherin expression. The molecular pathway analysis of the EA flower extract reveals that it can inhibit the phosphorylation of Erk1/Erk2, which could be behind the inhibition of angiogenesis, the initiation of MET event, and the overexpression of E-cadherin. …”
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  14. 14
    Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants

    Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants by Bin, Zhou

    Published 2017
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  15. 15
    Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants

    Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants by Bin, Zhou

    Published 2017
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  16. 16
    Theoretical and experimental insights into the C-steel aqueous corrosion inhibition at elevated temperatures in 1.0M HCl via multi-carbonyl Gemini cationic surfactants

    Theoretical and experimental insights into the C-steel aqueous corrosion inhibition at elevated temperatures in 1.0M HCl via multi-carbonyl Gemini cationic surfactants by El-Basiony, Nasser M.

    Published 2023
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  17. 17
    Use and assessment of “e-plastics” as recycled aggregates in cement mortar

    Use and assessment of “e-plastics” as recycled aggregates in cement mortar by Makri, Chrysanthi

    Published 2019
    “…The obtained results, for all RPs, (especially those of 7.5% and 10%) exhibited an increase in the CS of the specimens by 15.4% and 7.8%, respectively, with the MoE decreased in both cases by 18.1% and 23.8%, respectively. …”
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  18. 18
    The effects of oxygen concentration on in vitro output of prostaglandin E2 and interleukin-6 from human fetal membranes.

    The effects of oxygen concentration on in vitro output of prostaglandin E2 and interleukin-6 from human fetal membranes. by Al-Asmakh, Maha

    Published 2007
    “…The output of prostaglandin E(2) from non-activated fetal membranes in response to IL-1beta was decreased by approximately 80% at 16 and 24 h of culture, whereas the inhibition of IL-6 production was time-dependent, reaching 90% after 16 h and 50% after 24 h. …”
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  19. 19
    Fluorinated Benzofuran and Dihydrobenzofuran as Anti-Inflammatory and Potential Anticancer Agents

    Fluorinated Benzofuran and Dihydrobenzofuran as Anti-Inflammatory and Potential Anticancer Agents by Ayoub, Abeer J.

    Published 2023
    “…Their IC50 values ranged from 1.2 to 9.04 µM for interleukin-6; from 1.5 to 19.3 µM for Chemokine (C-C) Ligand 2; from 2.4 to 5.2 µM for nitric oxide; and from 1.1 to 20.5 µM for prostaglandin E2. …”
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  20. 20
    Salvia fruticosa Induces Vasorelaxation in Rat Isolated Thoracic Aorta: Role of the PI3K/Akt/eNOS/NO/cGMP Signaling Pathway

    Salvia fruticosa Induces Vasorelaxation in Rat Isolated Thoracic Aorta: Role of the PI3K/Akt/eNOS/NO/cGMP Signaling Pathway by Anwar, M. Akhtar

    Published 2017
    “…Prior exposure to PI3K inhibitors, wortmannin (0.1 µM) or LY294002 (10 µM), decreased cGMP accumulation and attenuated the SF-induced vasorelaxation by approximately 50% (Rmax). …”
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