Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit, Masania

“…Mice with ectopic expression of uncoupling protein-1 (UCP1) in skeletal muscle exhibit a healthy aging phenotype with increased longevity and resistance to impaired metabolic health. …”
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Exploring the evolution of <i>Acinetobacter baumannii</i> and <i>Pseudomonas aeruginosa</i> resistance during the COVID-19 era by Emine Sehmen (22457614)

“…</p><h3>Results</h3><p dir="ltr">The average age of the patients was 61.3 ± 21.9 years (range: 18–95), with a majority of 1306 (51.6%) being male. During the pandemic, <i>A. baumannii</i> isolates showed a significant increase in resistance rates for several antibiotics compared to the pre-pandemic period: imipenem (96% vs 35.1%), amikacin (84.1% vs 14.4%), ciprofloxacin (96.9% vs 36.9%), trimethoprim-sulfamethoxazole (66.4% vs 27%), and ceftazidime (96.5% vs 33.3%) (all with <i>P</i>< .001). …”

<i>Tujjar </i>in the Gulf: Changes in Political Influence by Lakshmi Venugopal Menon (15445334)

“…</p><h2 dir="ltr">Other Information</h2><p dir="ltr">Published in: Social Change and Transformation in the Gulf Region<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See chapter on publisher's website: <a href="https://dx.doi.org/10.1007/978-981-19-7796-1_5" target="_blank">https://dx.doi.org/10.1007/978-981-19-7796-1_5</a></p>…”

The impact of different acidic conditions and food substrates on <i>Listeria </i><i>monocytogenes</i> biofilms development and removal using nanoencapsulated carvacrol by Jina Yammine (17317048)

“…In food substrates, nanoencapsulated carvacrol induced lower log reductions (1.58–2.90) than the ones in TSB (2.02–3.61). These findings provide valuable insights into the impact of different acidic conditions on the development of <i>L. monocytogenes</i> biofilms on stainless steel surfaces and the potential application of nanoencapsulated carvacrol as a biofilm control agent in food processing environments.…”

Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1⁺/NKX6.1⁺ progenitors by Noura Aldous (15429873)

“…Single-cell analysis revealed high RFX6 expression levels in endocrine clusters across various hESC-derived pancreatic differentiation stages. Upon differentiating iPSCs lacking RFX6 into pancreatic islets, a significant decrease in PDX1 expression at the PF stage was observed, although this did not affect PPs co-expressing PDX1 and NKX6.1. …”

iPSCs derived from insulin resistant offspring of type 2 diabetic patients show increased oxidative stress and lactate secretion by Bushra Memon (4792767)

“…The IR-iPSCs had increased lactate secretion and a higher phosphorylation of AKT upon stimulation with insulin. …”

Downregulation of <i>CYP17A1</i> by 20-hydroxyecdysone: plasma progesterone and its vasodilatory properties by Maneera Y Aljaber (18278971)

“…Direct effects on muscle and mesenteric arterioles were assessed by myography. Results: CYP17A1 was downregulated in 20-hydroxyecdysone-treated mice compared with untreated group (p = 0.04), with an insignificant increase in plasma progesterone. …”

Elucidating the Probiotic Potential of <i>Lactobacillus</i> and <i>Bifidobacterium</i> Species in Modulating Glucose Metabolism and Inflammation in Gestational Diabetes Mellitus: A... by Sidra A Uzair (23124226)

“…Probiotic supplementation with <i>Lactobacillus</i> and <i>Bifidobacterium</i> species has potential in addressing GDM by modulating gut microbiota. …”

Suppression of GATA-3 increases adipogenesis, reduces inflammation and improves insulin sensitivity in 3T3L-1 preadipocytes by Layla Al-Mansoori (9522518)

Downregulation of Lymphoid enhancer‐binding factor 1 (<i>LEF‐1)</i> expression (by immunohistochemistry and/ flow cytometry) in chronic Lymphocytic Leukemia with atypical immunophe... by Dina S. Soliman (14779333)

“…Absence of <i>LEF-1</i> expression in CLL/SLL is correlated (<i>P</i> < .05) with downregulation of CD5, CD23, CD200, expression of FMC7, brighter expression of CD79b, brighter expression of surface light chain, increased prolymphocytes and lower Matutes score.…”

Soluble Neuropilin-1 Response to Hypoglycemia in Type 2 Diabetes: Increased Risk or Protection in SARS-CoV-2 Infection? by Abu Saleh Md Moin (6189512)

“…The Renin-Angiotensin System (RAS) is activated in type 2 diabetes (T2D); therefore, the aim of this study was to determine if hypoglycaemia-induced stress in T2D would potentiate serum NRP1(sNRP1) levels, reflecting an increased risk for SARS-CoV-2 infection.…”

Emerging Glycation-Based Therapeutics—Glyoxalase 1 Inducers and Glyoxalase 1 Inhibitors by Naila Rabbani (291722)

“…Glycation of DNA and the spliceosome contribute to an antiproliferative and apoptotic response of high, cytotoxic levels of MG. Glyoxalase 1 (Glo1) of the glyoxalase system has a major role in the metabolism of MG. …”

Pga1. (c2009) by Hashash, Rami A.

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Studies on Natural Extracts as Inhibitors of Mild Steel Corrosion in 1M HC1 Solution by Shanableh, Alaa

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Entry of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine into the rat brain by Riachi, N.J.

“…We studied blood-to-brain entry of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), 1-methyl-4-phenylpyridinium (MPP+) and butanol in anesthetized rats using the indicator-fractionation method with right atrial bolus injection. …”
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L1-CAM knock-down radiosensitizes neuroblastoma IMR-32 cells by simultaneously decreasing MycN, but increasing PTEN protein expression by Rached, Johnny

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Genomic characterization of plasmid-borne colistin resistance variants, mcr-1.1 and mcr-1.26, in multidrug-resistant Escherichia coli isolated from backyard farm animals by Dina, Daaboul

“…However, colistin resistance and the emergence of the mobile colistin resistance (mcr) genes have been increasingly documented in clinical and community settings, including in humans, animals, and the environment [ [1] , [2] , [3] ], which severely limits available antimicrobial options for addressing critical infections. …”
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Response of cauliflower (<i>Brassica oleracea</i> L.) to nitric oxide application under cadmium stress by Jing Ma (24574)

“…Our results illustrated that the increasing levels of Cd in the sand, significantly (P < 0.05) decreased shoot length, root length, shoot fresh weight, root fresh weight, shoot dry weight, root dry weight, germination percentage, germination index, mean germination time, time to 50% germination, chlorophyll a, chlorophyll b, total chlorophyll and carotenoid contents in all genotypes of B. oleracea. …”

Seizure-like behavior and hyperactivity in <i>napb</i> knockout zebrafish as a model for autism and epilepsy by Kyung Chul Shin (13913556)

“…In this study, we generated NAPB zebrafish model using CRISPR-Cas9-sgRNAs technology for gene editing of the two orthologs <i>napba </i>and <i>napbb</i>. We observed that napb crispants (CR) show shorter motor neuron axons length together with altered locomotion behavior, including significant increases in larvae total distance traveled, swimming velocity, and rotation frequency, indicating that these behavioral changes effectively mimic the human epileptic phenotype. …”

I know you are watching me by Abdel Wahab, Omar

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