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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
Published 2021“…This study aims to investigate the inhibitory effect of metformin on VISTA via AHR in melanoma cells (CHL-1, B16) and animal models. VISTA and AHR levels were assessed by qPCR, Western blot, immunofluorescence microscope, flow cytometry, and immunohistochemistry. …”
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Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy
Published 2019“…Cells were co-transfected with a C-terminal modified α-synuclein (SynT) and synphilin-1, and then treated with DHM (10 μM) and Sal B (50 μM) 16 hours after transfection; levels of α-synuclein aggregation decreased significantly (68% for DHM and 75% for Sal B). …”
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Adult appendicitis score versus Alvarado score: A comparative study in the diagnosis of acute appendicitis
Published 2023“…<h3><b>Background</b></h3><p dir="ltr">Acute Appendicitis (AA) is the most common abdominal surgical emergency. …”
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Central and peripheral muscle fatigue following repeated‐sprint running in moderate and severe hypoxia
Published 2020“…The decrease in potentiated twitch torque in SL (Δ = −13.3 ± 5.2 N m) was not different to MH (Δ = −13.3 ± 6.3 N m) but was lower than in SH (Δ = −16.1 ± 4 N m) from Pre- to Post-set 1 (interaction, <i>P</i> < 0.003). …”
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A robust experimental-based artificial neural network approach for photovoltaic maximum power point identification considering electrical, thermal and meteorological impact
Published 2020“…The results showed a decrease in the MSE of V<sub>mp</sub> by 74.3% (from 1.6 V to 0.411 V), and in the MSE of I<sub>mp</sub> by 95% (from 4.4e−6 A to 2.16e−7 A), respectively. …”
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The Effect of Olanzapine, Tart Cherry, Fish Oil and High Fat in the Composition of the Gut Microbiome in Obese Mice
Published 2022“…In comparing between LF and HF diet, <i>Faecalibaculum</i> was high in LF, whereas <i>Mucispirillum, Ruminiclostridium, </i>and<i> Roseburia</i> increased in HF diet.…”
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SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs
Published 2019“…The IC<sub>50</sub> values were found to be in the micromolar to submicromolar range. The <i>K</i><sub><em>i</em></sub> values of compound 16 were determined to be 0.047 and 0.020 μM for the inhibition of MAO-A and MAO-B, respectively. …”
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Modulation of gut microbiota: The effects of a fruits and vegetables supplement
Published 2022“…The gut microbiome composition, measured by 16S rDNA sequencing, showed no difference in both alpha and beta diversities, whereas the LEfse analysis revealed a microbial shift after the treatment, with a decreased abundance of the genus <i>Ruminococcus</i> from the Lachnospiraceae family (<i>p</i> = 0.009), and the unclassified genus from the family Erysipelotrichaceae (UC36, <i>p</i> = 0.003) in the FVS group compared with the PLA group (confirmed by SIAMCAT analysis, AUC = 74.1%). …”
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Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019
Published 2022“…We included International Classification of Diseases 9th edition codes 079.6, 466–469, 470.0, 480–482.8, 483.0–483.9, 484.1–484.2, 484.6–484.7, and 487–489 and International Classification of Diseases 10th edition codes A48.1, A70, B97.4–B97.6, J09–J15.8, J16–J16.9, J20–J21.9, J91.0, P23.0–P23.4, and U04–U04.9. …”
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