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Hyperhydration-induced decrease in urinary luteinizing hormone concentrations of Male athletes in doping control analysis
Published 2019“…Baseline urinary LH concentrations, expressed as the mean � SD for each individual, were within the acceptable physiological range (7.11 � 5.42 IU/L). …”
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Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling
Published 2019“…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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Effect of octylphenol polyethylene oxide on the corrosion inhibition of steel in 0.5 M H2SO4
Published 2004“…A non-ionic surfactant, octylphenol polyethylene oxide (OPPEO), was evaluated as an inhibitor for corrosion of low-carbon steel in 0.5M H 2SO4. …”
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An Eco-Friendly Quaternary Ammonium Salt as a Corrosion Inhibitor for Carbon Steel in 5 M HCl Solution: Theoretical and Experimental Investigation
Published 2022“…This study aims to investigate the performance of an environment-friendly Quaternium-22 (Q-22) surfactant which is widely used in cosmetics for C-steel corrosion inhibition in a 5 M HCl medium. Weight loss experiments were performed at different concentrations and immersion times, presenting a maximum efficiency at 2.22 mmol·L−1. …”
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Host genetic variants potentially associated with SARS-CoV-2: A multi-population analysis
Published 2020“…Analysis of Qatari genomes revealed significantly lower AF of risk variants linked to SARS-CoV-1 severity (CCL2, MBL, CCL5, AHSG, and IL4) compared to that of 1000Genome and/or the EAS population (up to 25-fold change). …”
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Host Genetic Variants Potentially Associated With SARS-CoV-2: A Multi-Population Analysis.
Published 2020“…Remarkably, Africans seem to carry extremely lower frequencies of SARS-CoV-1 susceptibility alleles, reaching to 32-fold decrease compared to other populations. …”
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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
Published 2025“…Here, we report the engineering of a Bioluminescence Resonance Energy Transfer (BRET)-based SARS-CoV-2 main protease (Mpro) biosensor containing the Mpro N-terminal autocleavage sequence in tandem and a nanobody that shows an enhanced rate of Mpro-mediated proteolytic cleavage. …”
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The impact of COVID-19 pandemic lockdown on smoking habits and lifestyle: A cross-sectional study
Published 2023“…Females who started smoking last year were 2.6-fold more than males (p < 0.0001). We also noticed that there is a significant relationship between those who started smoking and are <18 years, living in a family consisting of seven members or more, being unemployed, having a diploma or bachelor's degree in a health-related major, having no chronic illnesses, increasing of daily meals or night meals, almost daily sugar intake, starting to follow social media account concerning physical activity, exercising once or twice a week, and sleeping more hours per day since the beginning of the pandemic (p < 0.01). …”
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PRMT5-PTEN molecular pathway regulates senescence and self-renewal of primary glioblastoma neurosphere cells
Published 2017“…Our results uncover a very significant role for PRMT5 in GBMNS self-renewal capacity and proliferation. …”
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Sliding mode control based dtc of sensorless parallel-connected two five-phase pmsm drive system
Published 2018“…This paper presents a sensorless direct torque control (DTC) combined with sliding mode approach (SM) and space vector modulation (SVM) to achieve mainly a high performance and reduce torque and flux ripples of a parallel-connected two five-phase permanent magnet synchronous machine (PMSM) drive system. …”
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Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar
Published 2021“…Human parvovirus (B19V) is the causative agent of erythema infectiosum in children and is linked to a wide range of clinical manifestations. …”
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Wind energy potential along the onshore and offshore Qatar
Published 2020“…cant increase or decrease of wind power around Qatar in the last 40 years in most of the locations, while there is a slight decreasing trend in the o?…”
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Structural evaluation, preliminary in vitro stability and electrochemical behavior of apatite coatings on Ti6Al4V substrates
Published 2016“…Results showed the formation of an amorphous apatite layer onto the alloy, that was further shown to partially crystallize upon heat treatment. As a result of SBF treatment, the apatite layer was found to remodel through a dissolution-precipitation mechanism due to its amorphous and non-stoichiometric nature, forming a smooth layer with better homogeneity and decreased surface roughness. …”
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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov...
Published 2023“…Among VN individuals, anti-S1 IgA levels began to decrease significantly (1.4-fold; p = 0.007) after two months, and both NtAb and S-RBD IgG levels began to decline significantly (NtAb: 2.0-fold; p = 0.042, S-RBD IgG: 2.4-fold; p = 0.035) after three months. …”
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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov...
Published 2023“…Among VN individuals, anti-S1 IgA levels began to decrease significantly (1.4-fold; p = 0.007) after two months, and both NtAb and S-RBD IgG levels began to decline significantly (NtAb: 2.0-fold; p = 0.042, S-RBD IgG: 2.4-fold; p = 0.035) after three months. …”
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