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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
Published 2025“…We envisage that the NB2E3 nanobody-2× Mpro biosensor engineered here will be useful in drug discovery and functional characterization of Mpro mutants in newly emerging SARS-CoV-2 variants as well as in detecting SARS-CoV-2 infection in a point-of-care testing (POCT) format.…”
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Soluble Neuropilin-1 Response to Hypoglycemia in Type 2 Diabetes: Increased Risk or Protection in SARS-CoV-2 Infection?
Published 2021“…</p><h3>Conclusion</h3><p dir="ltr">Hypoglycemia potentiated both plasma sNRP1 level elevation and its ligands VEGF and SEMA3A, likely through an ADAM9-mediated mechanism that was not associated with RAS overactivity or ACEi therapy; however, whether this is protective or promotes increased risk for SARS-CoV-2 infection in T2D is unclear.…”
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The emergence of new SARS-CoV-2 variant (Omicron) and increasing calls for COVID-19 vaccine boosters-The debate continues
Published 2022“…The Delta variant was reported to have increased transmissibility, higher viral load [4] and high rates of reinfection [5]. …”
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HbA1c over 8.5% is not predictive of increased infection rate following penile prosthesis implant surgery in diabetic patients with erectile dysfunction
Published 2021“…Penile prosthesis implantation infection rate was 0.83% (5/599), while the mean haemoglobinA1c level was 7.58 ± 1.45 mmol/l (range: 4.1–12.6). …”
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Percutaneous coronary intervention can be safely performed with left ventricular thrombus without increasing stroke risk: A 5-year retrospective review using real-world data
Published 2023“…<h3>Introduction</h3><p dir="ltr">Left ventricular thrombus (LVT) increases the risk of ischemic stroke. However, it remains uncertain if the percutaneous coronary intervention (PCI) in the confirmed LVT setting further augments the stroke risk. …”
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Assessment of tropospheric NO<sub>2</sub> concentrations over greater Doha using Sentinel-5 TROPOspheric monitoring instrument (TROPOMI) satellite data: Temporal analysis, 2018–202...
Published 2024“…Analysis of annual NO<sub>2</sub> levels from 2019 to 2023 showed an increase in 2022 compared to that of the previous three years and a clear decrease in 2023 post the completion of the world cup preparations and hosting. …”
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Increasing efficiency of atriums in hot, arid zones
Published 2019“…The light sensors and the roof’s thermal insulation resulted in the highest reduction of the atrium’s energy, 8.5% and 7.5%, respectively. Increasing the number of floors reduced the energy consumption by 5% per unit area. …”
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Cardiac phosphodiesterases are differentially increased in diabetic cardiomyopathy
Published 2021“…Moreover, we noted an early and specific upregulation of cardiac PDE1A, PDE2A, PDE4B, PDE4D and PDE5A expression at week 4, followed by increases in PDE3A levels in diabetic hearts at week 8. …”
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Drivers of MERS-CoV Emergence in Qatar
Published 2018“…The discovery and exploitation of oil and gas led to a 5-fold increase in Qatar GDP coupled with a 7-fold population growth in the past 30 years. …”
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SARS-CoV-2 Variants in Lebanon
Published 2024“…Co-infections of SARS-CoV-2 with influenza viruses were detected and led to increased infectivity and SARS-CoV-2 viral load. …”
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Walking around the preferred speed: examination of metabolic, perceptual, spatiotemporal and stability parameters
Published 2024“…Results indicated a significant main effect of speed on all studied variables. While metabolic, perceptual and spatiotemporal values were sensitive to the smallest change in speed (i.e., 0.5 km·h<sup>−1)</sup>, a significant increase in the rate of carbohydrate oxidation and decrease in % fat oxidation were only observed at speeds above PWS. …”
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Effect of speed and gradient on plantar force when running on an AlterG® treadmill
Published 2021“…Gradient made little difference except for a downhill grade of − 5% decreasing force peaks as compared to level or uphill running.…”
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Host Genetic Variants Potentially Associated With SARS-CoV-2: A Multi-Population Analysis
Published 2020“…<h3>Background</h3><p dir="ltr">Clinical outcomes of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) showed enormous inter-individual and inter-population differences, possibly due to host genetics differences. Earlier studies identified single nucleotide polymorphisms (SNPs) associated with SARS-CoV-1 in Eastern Asian (EAS) populations. …”
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Thermoelectric power of (Cu0.5Tl0.5)-1223 superconducting phase added with BaSnO3 nanoparticles
Published 2017“…Superconducting transition temperature (Tc) increases up to 117.5 for x = 0.25 wt.% and then it decreases with further x addition. …”
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