Nitric Oxide Releasing Hydrogel Nanoparticles Decreases Epithelial Cell Injuries Associated With Airway Reopening. by Shurbaji, Samar

Get full text
Get full text

Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling by Chung, Jihyun

“…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …”
Get full text
Get full text

A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate by Geethakumari, Anupriya M

“…We envisage that the NB2E3 nanobody-2× Mpro biosensor engineered here will be useful in drug discovery and functional characterization of Mpro mutants in newly emerging SARS-CoV-2 variants as well as in detecting SARS-CoV-2 infection in a point-of-care testing (POCT) format.…”
Get full text
Get full text
Get full text

Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... by Ganji, Vijay

Get full text
Get full text

Effects of SARS-CoV-2 Alpha, Beta, and Delta variants, age, vaccination, and prior infection on infectiousness of SARS-CoV-2 infections by Qassim, Suelen H.

“…Using the cycle threshold (Ct) value of an RT-qPCR-positive test to proxy the inverse of infectiousness, we investigated infectiousness of SARS-CoV-2 infections by variant, age, sex, vaccination status, prior infection status, and reason for testing in a random sample of 18,355 RT-qPCR-genotyped infections. …”
Get full text
Get full text
Get full text

Host genetic variants potentially associated with SARS-CoV-2: A multi-population analysis by Smatti, Maria K.

“…Earlier studies identified single nucleotide polymorphisms (SNPs) associated with SARS-CoV-1 in Eastern Asian (EAS) populations. In this report, we aimed at exploring the frequency of a set of genetic polymorphisms that could affect SARS-CoV-2 susceptibility or severity, including those that were previously associated with SARS-CoV-1. …”
Get full text
Get full text

Host Genetic Variants Potentially Associated With SARS-CoV-2: A Multi-Population Analysis. by Smatti, Maria K

“…Earlier studies identified single nucleotide polymorphisms (SNPs) associated with SARS-CoV-1 in Eastern Asian (EAS) populations. In this report, we aimed at exploring the frequency of a set of genetic polymorphisms that could affect SARS-CoV-2 susceptibility or severity, including those that were previously associated with SARS-CoV-1. …”
Get full text
Get full text

Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... by Salma, Younes

“…MethodThe study comprised fully-vaccinated naïve individuals (VN; n = 596) who had no history of SARS-CoV-2 infection, and received two doses of either BNT162b2 or mRNA-1273, and naturally infected individuals who had a documented history of SARS-CoV-2 infection and no vaccination record (NI cohort; n = 218). …”
Get full text
Get full text
Get full text

Impact of SARS-CoV-2 on Ambient Air Quality in Northwest China (NWC) by Zaib, Shah

“…To prevent the spread of the SARS-CoV-2 outbreak, China imposed a countrywide lockdown that significantly improved the air quality. …”
Get full text
Get full text

Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... by Salma, Younes

“…MethodThe study comprised fully-vaccinated naïve individuals (VN; n = 596) who had no history of SARS-CoV-2 infection, and received two doses of either BNT162b2 or mRNA-1273, and naturally infected individuals who had a documented history of SARS-CoV-2 infection and no vaccination record (NI cohort; n = 218). …”
Get full text
Get full text
Get full text

Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar by Abdelrahman, Doua

“…Human parvovirus (B19V) is the causative agent of erythema infectiosum in children and is linked to a wide range of clinical manifestations. …”
Get full text
Get full text

A 5-year trend in the use of sodium-glucose co-transporter 2 inhibitors and other oral antidiabetic drugs in a Middle Eastern country by Zaghloul, Nancy

“…Background: Sodium glucose co-transporter 2 inhibitors (SGLT2is) are a novel class of oral antidiabetic drugs. …”
Get full text
Get full text

Turning point in COVID-19 severity and fatality during the pandemic: a national cohort study in Qatar by Chemaitelly, Hiam

“…Conclusion The conclusion of the first omicron wave was a turning point in the severity of the pandemic. …”
Get full text
Get full text

The impact of COVID-19 pandemic lockdown on smoking habits and lifestyle: A cross-sectional study by Khamees, Almu'atasim

Get full text
Get full text

SARS-CoV-2: An Analysis of the Vaccine Candidates Tested in Combatting and Eliminating the COVID-19 Virus by Elmancy, Laila

“…Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2), better known as COVID-19, is a highly contagious virus, transferable via air droplets from close human-human contact. …”
Get full text
Get full text
Get full text

Effects of a single dose of ivermectin on viral and clinical outcomes in asymptomatic sars-cov-2 infected subjects: A pilot clinical trial in lebanon by Samaha, Ali A.

“…Methods: A randomized controlled trial was conducted in 100 asymptomatic Lebanese subjects that have tested positive for SARS-CoV2. …”
Get full text
Get full text

Blue photobiomodulation LED therapy impacts SARS-CoV-2 by limiting its replication in Vero cells by Zupin, L.

“…Our in vitro findings could represent the starting point for translational applications of PBMT as a supportive approach to fight SARS-CoV-2.…”
Get full text
Get full text
Get full text

Reducing energy consumption of CO2 desorption in CO2-loaded aqueous amine solution using Al2O3/HZSM-5 bifunctional catalysts by Zhang X.

“…The aim of this work is to find a potential way for great decrease in CO2 capture energy requirement. …”
Get full text
Get full text

Understanding the False Positive of Modified Martensitic Steels in Sweet & Sour Service Conditions Using a Point Defect Model Perspective by Martinez, Alan

“…These results indicate a critical point in temperature in the tests with only CO2, where resistance to pitting susceptibility is maximized due to a decrease in the cation vacancy diffusivity.…”
Get full text

A comparative study of the growth of Tetraselmis sp. in large scale fixed depth and decreasing depth raceway ponds by Das, Probir

Get full text
Get full text