Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit, Masania

“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit, Masania

“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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Awareness of disabilities in pharmacy program recruitment material: are we doing enough? by Hussain, Farhat Naz

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Uncovering the Epigenetic Contribution of Protein Arginine Methyltransferase 5 (PRMT5) during Zebrafish Cardiomyogenesis by Zakaria, Zain Zaki

“…The reduction of the expression of PRMT5 also resulted in a 4-fold decrease in the rate of hatching and had negative impacts on locomotion and tail flicking in PRMT5 morphants. …”
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Quality improvement can decrease blood delivery turnaround time: Evidence from a single tertiary-care academic medical center by Hammad Y.A.

“…The transport time significantly decreased from an initial majority of > 15 mins duration, to a majority of < 15 mins transport time after the second audit; there was a 50% improvement in 30 mins response time; and the percentage of requests processed in < 10 mins were significantly higher after the second audit. …”
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Ecotoxicological Assessment of Thermally- and Hydrogen-Reduced Graphene Oxide/TiO₂ Photocatalytic Nanocomposites Using the Zebrafish Embryo Model. by Al-Kandari, Halema

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Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... by Ganji, Vijay

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Host genetic variants potentially associated with SARS-CoV-2: A multi-population analysis by Smatti, Maria K.

“…Remarkably, Africans seem to carry extremely lower frequencies of SARS-CoV-1 susceptibility alleles, reaching to 32-fold decrease compared to other populations. …”
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Host Genetic Variants Potentially Associated With SARS-CoV-2: A Multi-Population Analysis. by Smatti, Maria K

“…Remarkably, Africans seem to carry extremely lower frequencies of SARS-CoV-1 susceptibility alleles, reaching to 32-fold decrease compared to other populations. …”
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Trends in fecal carriage of carbapenemase-producing Enterobacterales in children before and after the implementation of international travel restrictions in response to COVID-19 by Andrés, Pérez-López

“…Furthermore, CPE carriage rate decreased 3.6-fold (95% CI, 1.5–10.5; P < 0.001) after March 15, 2020. …”
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The impact of COVID-19 pandemic lockdown on smoking habits and lifestyle: A cross-sectional study by Khamees, Almu'atasim

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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... by Salma, Younes

“…At the 7th month, there was a significant decline in antibody responses among VN individuals, but not NI individuals, with a minimum decrease of 3.7-fold (p < 0.001). Among VN individuals, anti-S1 IgA levels began to decrease significantly (1.4-fold; p = 0.007) after two months, and both NtAb and S-RBD IgG levels began to decline significantly (NtAb: 2.0-fold; p = 0.042, S-RBD IgG: 2.4-fold; p = 0.035) after three months. …”
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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... by Salma, Younes

“…At the 7th month, there was a significant decline in antibody responses among VN individuals, but not NI individuals, with a minimum decrease of 3.7-fold (p < 0.001). Among VN individuals, anti-S1 IgA levels began to decrease significantly (1.4-fold; p = 0.007) after two months, and both NtAb and S-RBD IgG levels began to decline significantly (NtAb: 2.0-fold; p = 0.042, S-RBD IgG: 2.4-fold; p = 0.035) after three months. …”
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In vitro evaluation of Neosetophomone B inducing apoptosis in cutaneous T cell lymphoma by targeting the FOXM1 signaling pathway by Kuttikrishnan, Shilpa

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Anti-Neoplastic Effects of Annonacin against Renal Cell Carcinoma by Munusamy, Shankar

“…Results: hour annonacin treatment caused a significant and dose-dependent decrease in the viability of CaKi-2 cells, i.e., 42% in 0.5 ?…”
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Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2. by P, Sneha

“…Molecular docking analysis revealed a decrease in interaction between the protein and ATP in all the 3 mutations, and molecular dynamic simulations of 50 ns showed a loss of stability and compactness in the mutant proteins. …”
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Correlation between delta-endotoxin and proteolytic activities produced by Bacillus thuringiensis var. kurstaki growing in an economic production medium by Ennouri, Karim

“…Maximal protease activity (540-2468 UI) obtained by BUPM5-1 and BUPM5-2 was 2.34-fold and 10.7-fold, respectively, more than that obtained by the wild strain BUPM5 with a drastic decrease of their delta-endotoxin production. …”
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AMPK Activation Attenuates Albumin-induced Alterations in Renal Tubular Cells In Vitro by Allouch, Soumaya

“…In addition, 2.5-fold increase in LC3-II expression was noted. …”
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Reinforcement of polyacrylamide-co-tert-butyl acrylate base gel using nanosilica for conformance control at low and high reservoir temperatures by Shamlooh M.

“…In this study, different ratios of polymer to crosslinker were investigated to choose the optimum combination. Then, nanosilica (NS) with different sizes (20, 50 and 85 nm) was added to the polymeric formulation with the inorganic crosslinker (CrAc3) to study the effect of silica content and size on gel strength. …”
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The Cellular Interplay Between Na+/H+ Exchanger Isoform I and Osteopontin in Cardiac Hypertrophy by Abdelaziz, Iman Ahmed

“…This was significantly abolished in the presence of siRNA-OPN (20.2 fold decrease±0.12 of control) and (68.5±0.24% vs. 586.5±103.54% NHE1-infected). …”
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