Decreased Expression and Activity of cAMP Phosphodiesterases in Cardiac Hypertrophy and Its Impact on β-Adrenergic cAMP Signals by Abi-Gerges, Aniella

“…Methods and Results: Cardiac hypertrophy was induced in rats by thoracic aortic banding over a time period of 5 weeks and was confirmed by anatomic measurements and echocardiography. Ex vivo myocardial function was evaluated in Langendorff-perfused hearts. …”
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Hypospadias Reconstruction Training: Development of an Ex-Vivo Model for Objective Evaluation of Surgical Skills by Abbas, Tariq

“…Surgeons wore wireless EMG and accelerometer sensors on their dominant hand while performing tasks on ex-vivo cadaveric calf penises. The study focused on 4 skills as follows: urethral mobilization, dorsal inlay graft harvest/implantation, meatal-based flap urethroplasty, and dorsal plication. …”
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Hypospadias Reconstruction Training: Development of an Ex-Vivo Model for Objective Evaluation of Surgical Skills by Tariq Abbas (368053)

“…Surgeons wore wireless EMG and accelerometer sensors on their dominant hand while performing tasks on ex-vivo cadaveric calf penises. The study focused on 4 skills as follows: urethral mobilization, dorsal inlay graft harvest/implantation, meatal-based flap urethroplasty, and dorsal plication. …”

Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway by Olfa Khalifa (10914452)

“…Additionally, after β-catenin silencing, OA treatment significantly increased the expression of nuclear transcription factors SREBP-1 and TCF4, whereas Ex-4 significantly decreased this upregulation. …”

Deep Reinforcement Learning Powered IRS-Assisted Downlink NOMA by Muhammad Shehab (16904880)

Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4 by Olfa Khalifa (10914452)

“…</p> <p>Results: Treatment with 200nM Ex-4 for 3h decreased the OA-induced lipid buildup significantly (p<0.05). …”

A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate by Geethakumari, Anupriya M

“…We envisage that the NB2E3 nanobody-2× Mpro biosensor engineered here will be useful in drug discovery and functional characterization of Mpro mutants in newly emerging SARS-CoV-2 variants as well as in detecting SARS-CoV-2 infection in a point-of-care testing (POCT) format.…”
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Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis by Meritxell Espino‐Guarch (22565774)

“…Decreased proteolysis in LAT2KO animals was associated with increased mTORC1 translocation to the lysosome (mTORC1‐Lamp1 colocalization in fasted LAT2KO muscles was 1.23‐fold, <i>p</i> < 0.0001). …”

Investigation of the Effect of Exendin-4 on Oleic Acid-Induced Steatosis in HepG2 Cells Using Fourier Transform Infrared Spectroscopy by Olfa Khalifa (10914452)

“…Analysis of the Oil Red O staining showed that Ex-4 significantly reduces steatosis. This reduction was confirmed by FTIR analysis, as the phospholipid band (C=O) at 1740 cm−1 in Ex-4 treated cells is significantly decreased compared to steatotic cells. …”

Dividend policy and corporate investment under information shocks by Harakeh, Mostafa

“…Then, I find that the constraining effect of dividends on investments declines following the information shock, especially among firms with higher levels of information asymmetry ex-ante. …”
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Allelopathic Effects of the Invasive Prosopis juliflora (Sw.) DC. on Native Plants: Perspectives toward Agrosystems by Shazia Bibi (16500318)

“…The seed germination and radicle length of S. aegyptica and H. perfoliata were significantly decreased at 2 mg mL−1 of extract of P. juliflora. …”

A new method for broad‐scale modeling and projection of plant assemblages under climatic, biotic, and environmental cofiltering by Alessandro Ferrarini (3951098)

“…Our model explained presences and absences of 175 plant species in 608 plots with >87% cross-validated accuracy, predicted decreases in <i>α, β</i>, and <i>γ</i> diversity by 2040 under both moderate and extreme climate scenarios, and identified likely advantaged and disadvantaged plant species under climate change. …”

Dynamics of Neisseria gonorrhoeae transmission among female sex workers and clients: A mathematical modeling study by Houssein H., Ayoub

“…Increasing condom use from 10 % to 50 % lowers NG prevalence among FSWs, clients, and their spouses from 12.2 % to 6.4 %, 1.2 % to 0.5 %, and 0.4 % to 0.2 %, respectively. …”
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Application of an empirical transport model to simulate retention of nanocrystalline titanium dioxide in sand columns by Choy, Christine Chin

“…Most of the nanoparticles remained in the sand columns, with an increasing then decreasing retained solids pattern. Application of a one-dimensional advection–dispersion flow model, that included two empirical kinetic terms to account for particle retention in the porous media, produced data fits that followed the general trend of the data, but did not truly capture the concentration maxima in the data sets. …”
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State of Global Financial Crime In-­depth Analysis on GCC Countries by Odeh, Layan Mazen

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Association Between Three-Months Vitamin D Supplementation and Depressive Symptomatology incidence among Saudi Arabian Adults by Khaddaj, Rashel

“…The mean baseline 25(OH)D3 concentration was 16.92±7.23ng/ml in the vitamin D group and 16.44±5.91 ng/ml in the control group (p =0.76). …”
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Interleukin-35 and Thymoquinone nanoparticle-based intervention for liver protection against paracetamol-induced liver injury in rats by Maisa Siddiq Abduh (16381125)

“…Group IV (PAR) received 600 mg/kg of PAR orally; V (PAR + IL-35) and VI (PAR + TYHO); rats received 600 mg/kg of PAR orally and i.p injection of IL-35 (200 ng/kg) or THYO (0.5 mg/kg), respectively. …”

The effects of long-term testosterone treatment on endocrine parameters in hypogonadal men: 12-year data from a prospective controlled registry study by Aksam Yassin (14779204)

“…This was accompanied by an increase in estradiol levels by 14.9 pmol/L (<i>p</i> < 0.0001), and decreases in progesterone (0.2 ng/mL, <i>p</i> < 0.0001), LH (10.4 U/L, <i>p</i> < 0.0001) and FSH (8.4 U/L, <i>p</i> < 0.0001) were demonstrated at 12-years. …”

Hepatitis serology predicts tumor and liver-disease characteristics but not prognosis after resection of hepatocellular carcinoma by Abdalla, Eddie

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The Effect of Atorvastatin (and Subsequent Metformin) on Adipose Tissue Acylation-Stimulatory-Protein Concentration and Inflammatory Biomarkers in Overweight/Obese Women With Polyc... by Thozhukat Sathyapalan (704787)

“…</p><h3>Results</h3><p dir="ltr">There was significant reduction in ASP (156.7 ± 16.2 vs. 124.4 ± 14.8 ng/ml p <0.01), IL-6 (1.48 ± 0.29 vs.0.73 ± 0.34 pg/ml p = 0.01) and MCP-1 (30.4 ± 4.2 vs. 23.0 ± 4.5 pg/ml p = 0.02) after 12 weeks of atorvastatin that was maintained subsequently with 12 weeks treatment with metformin. …”