Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit, Masania

“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit Masania (7164239)

“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”

Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex by Wesam S. Ahmed (10170053)

“…Here, we dissect the mechanism underlying the increased binding affinity of the N501Y mutant for ACE2 using molecular dynamics (MD) simulations of the available ACE2-S1-RBD complex structure (6M0J) and show a prolonged and stable interfacial interaction of the N501Y mutant S1-RBD with ACE2 compared to the wild type S1-RBD. …”

Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex by Wesam S. Ahmed (10170053)

“…<p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences <a href="https://dx.doi.org/10.3389/fmolb.2022.846996" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.846996</a>, published online 22 July 2022.…”

apoA2 correlates to gestational age with decreased apolipoproteins A2, C1, C3 and E in gestational diabetes by Manjunath Ramanjaneya (14603468)

“…</p><h3>Conclusions</h3><p dir="ltr">Apoproteins apoA2, apoC1, apoC3 and apoE are decreased in women with GDM and may have a role in inflammation, as apoA2 and C3 correlated with CRP. …”

A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. …”

Genome-Wide Association Study of Vitamin D Deficiency in the Middle East With a Relevant Characterization of the Novel <i>SDR42E1 </i>Gene by Nagham Nafiz Ahmad Hendi (19938204)

“…Cellular viability also decreased significantly after the knockout of SDR42E1 in the HCT116 cells.…”

eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways by Zvi Cramer (10742876)

“…Previously, we demonstrated that Pateamine A (PatA), a compound that targets eukaryotic initiation factor 4A (eIF4A), could prevent muscle wasting by modulating the translation of the inducible Nitric Oxide Synthase (iNOS) mRNA. …”

Effect of AlN nanoparticle concentration in the electrolyte on corrosion resistance and mechanical properties of the electrodeposited composite coatings by Khan, M.S.

“…Furthermore, the coatings displayed improved mechanical strength, with the Ni-P-0.4 g/L AlN composite coating registering the highest hardness at 660 HV0.025. …”
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Effect of AlN nanoparticle concentration in the electrolyte on corrosion resistance and mechanical properties of the electrodeposited composite coatings by M.S. Khan (22047413)

“…Furthermore, the coatings displayed improved mechanical strength, with the Ni-P-0.4 g/L AlN composite coating registering the highest hardness at 660 HV0.025. …”

Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies by Fawaz E., Alanazi

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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

Enhanced thermoelectric properties of Bi₂Te_2.55Se_0.45 nanocomposites using eco-friendly Eocene Midra Shale palygorskite nanofillers: A sustainable... by Farah M. El-Makaty (14157090)

“…<p dir="ltr">This paper investigates the influence of incorporating Eocene Midra Shale (EMS), consisting of 1D palygorskite and 2D irregular dolomite flakes, on the thermoelectric properties of an n-type Bi₂Te_2.55Se_0.45 alloy. …”

Masked phenomenon: renal and cardiovascular complications; review and updates by Elmukhtar Habas (14777677)

Combined Noncoding RNA-mRNA Regulomics Signature in Reprogramming and Pluripotency in iPSCs by Salam Salloum-Asfar (656363)

“…From each fibroblast (N = 4), three iPSC clones were examined (N = 12). iPSCs and original fibroblasts expressed miRNA clusters differently and miRNA clusters were compared to mRNA hits. …”

A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate by Geethakumari, Anupriya M

“…Specifically, we designed Mpro biosensors containing 2×, 4× and 8× repeats of Mpro N-terminal autocleavage sequences and a combination of Mpro cleavage sequences containing a total of 12 cleavage sites sandwiched between mNeonGreen (mNG) and NanoLuc (NLuc). …”
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Response of cauliflower (<i>Brassica oleracea</i> L.) to nitric oxide application under cadmium stress by Jing Ma (24574)

“…The present study was conducted using four different genotypes of B. oleracea named as FD-3, FD-4, FD-2 and Ceilo Blanco which were subjected to the Cd stress at various concentrations i.e., 0, 5, 10 and 20 µM with or without the application of NO i.e., 0.10 mM in the sand containing nutrient Hoagland’s solution. …”

Dietary Curcumin Nanoparticles Improve Growth Performance, Oxidative Status and Immune Response of European Seabass (<i>Dicentrarchus Labrax</i>) by Albandari Bin-Ammar (16381128)

“…Fish fed with CURNPS at various levels exhibited remarkable increase in digestive enzymes (amylase and lipase), immune markers (immunoglobulin G (IgG), lysozyme and phagocytic indices), and antioxidant enzymes (superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx)). A noticeable decrease (P<0.05) in malondialdehyde (MDA) and considerable upregulation of hepatic insulin-like growth factor 1 (IGF1) and interleukin-1beta (IL-1β) mRNA levels were found in CURNPs-supplemented fish in a dose-dependent manner. …”

Development of a thermodynamical approach for the prediction of the bulk modulus of spherical cubic silicon carbide <i>(β−SiC)</i> nanosolids by Esam H. Abdul-Hafidh (19420882)

“…<p dir="ltr">A direct thermodynamical model is developed, aiming at predicting the mechanical properties (i.e. bulk modulus, <i>B</i>_<em>T</em><i> </i>) of spherical SiC nanoparticles (NPs), as a function of both temperature and pressure that were varied within 273 − 1673 K and 0 − 70 GPa, respectively. …”

SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs by Raed Shalaby (3756112)

“…Our results revealed that these selected chalcone analogs increased dopamine levels in the rat hepatoma (H4IIE) cells and decreased the relative mRNA expression of the MAO-B enzyme.…”