Fourier-Transform Infrared Imaging Spectroscopy and Laser Ablation -ICPMS New Vistas for Biochemical Analyses of Ischemic Stroke in Rat Brain by Mohamed H. M. Ali (5768066)

“…Areas close to the stroke focus experienced decrease in the lipid and lipid acyl contents associated with an increase in lipid ester, olefin, and methyl bio-contents with a novel finding of Aβ1-42 in the PL-GM and L-WM. …”

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit Masania (7164239)

“…Decreased formation and increased clearance of MG-derived AGEs may be associated with healthy aging in the HSA-mUCP1 mouse.…”

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit, Masania

“…Decreased formation and increased clearance of MG-derived AGEs may be associated with healthy aging in the HSA-mUCP1 mouse.…”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex by Wesam S. Ahmed (10170053)

“…Here, we dissect the mechanism underlying the increased binding affinity of the N501Y mutant for ACE2 using molecular dynamics (MD) simulations of the available ACE2-S1-RBD complex structure (6M0J) and show a prolonged and stable interfacial interaction of the N501Y mutant S1-RBD with ACE2 compared to the wild type S1-RBD. …”

Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex by Wesam S. Ahmed (10170053)

Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

Combined Noncoding RNA-mRNA Regulomics Signature in Reprogramming and Pluripotency in iPSCs by Salam Salloum-Asfar (656363)

“…Decreased levels of let-7a-5p showed an increase of SP8 as described previously. …”

Energy-Efficient Cell Association and Load Balancing for Low Battery Users in Heterogeneous Cellular Networks by Abdul Qadeer Khan (22502168)

“…This paper proposes improved cell association schemes based on the battery levels of UE and Deep Q-learning (DQL) to achieve load balancing and to decrease the power consumption of Low Battery Users (LBUs). …”

A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate by Geethakumari, Anupriya M

“…Specifically, we designed Mpro biosensors containing 2×, 4× and 8× repeats of Mpro N-terminal autocleavage sequences and a combination of Mpro cleavage sequences containing a total of 12 cleavage sites sandwiched between mNeonGreen (mNG) and NanoLuc (NLuc). Gaussian accelerated molecular dynamics (GaMD) simulations of the predicted alpha-helical synthetic Mpro cleavage sequences revealed a dynamic nature of the cleavage sequences, which is critical for their efficient cleavage, and a relatively short end-to-end distances, which is required for high BRET. …”
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SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs by Raed Shalaby (3756112)

“…Our results revealed that these selected chalcone analogs increased dopamine levels in the rat hepatoma (H4IIE) cells and decreased the relative mRNA expression of the MAO-B enzyme.…”

The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... by Wesal Habbab (17346961)

“…In this study we recorded maximum increase in total PP2A at 3 µM sodium selenate in a neuron cell line. In conjunction with these data, whole-cell electrophysiological studies revealed that this concentration had maximum effect on membrane potentials, conductance and currents. …”

Characterizing the Protein Coding RNAs (mRNA) and Long Non-Coding RNAs (LncRNAs) in Chemo Resistant Triple Negative Breast Cancer by Ahmed Mahmoud Mahmoud Mohamed Kardousha (19926096)

“…In current study, we investigated the expression of protein coding messenger RNAs (mRNAs) and long noncoding RNAs (lncRNAs) in doxorubicin-resistant MDA-MB-231 cell model. …”

Using artificially generated pictures in customer-facing systems: an evaluation study with data-driven personas by Joni Salminen (7434770)

Impact of trace noble metals on the catalytic performance of LaNiMgO towards methane dry reforming by Mohamed, Assem T.

“…On the other hand, at the same time-on-stream LaNiMgO-Rh lost 0.3 and 0.7 % of its maximum CO2 and CH4 conversions, respectively.In durability measurements, and after 140h LaNiMgO-Rh exhibited slight decay in the CO2 conversion from 77.6 % to 70.5%, the CH4 conversion decreased from 72.3% to 64.2%. …”
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Impact of trace noble metals on the catalytic performance of LaNiMgO towards methane dry reforming by Yahia H. Ahmad (14340210)

“…In durability measurements, and after 140h LaNiMgO-Rh exhibited slight decay in the CO₂ conversion from 77.6 % to 70.5%, the CH₄ conversion decreased from 72.3% to 64.2%. …”

Theoretical and experimental insights into the C-steel aqueous corrosion inhibition at elevated temperatures in 1.0 M HCl via multi-carbonyl Gemini cationic surfactants by Nasser M. El-Basiony (18021631)

“…The Tafel polarization revealed that at 0.1 mM of LAPG and MAPG, the corrosion current density (i _corr) of CS was reduced to the lowest extent (75.56 and 53.82 μA cm⁻²) compared to 529.3 μA cm⁻² in the absence of the inhibitors. …”

Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis by Meritxell Espino‐Guarch (22565774)

“…Ex vivo incubation of LAT2KO muscle with rapamycin recovered proteolysis function, demonstrating a mTORC1‐dependent pathway. Decreased proteolysis in LAT2KO animals was associated with increased mTORC1 translocation to the lysosome (mTORC1‐Lamp1 colocalization in fasted LAT2KO muscles was 1.23‐fold, <i>p</i> < 0.0001). …”

SARS‐CoV‐2 infection triggers more potent antibody‐dependent cellular cytotoxicity (ADCC) responses than mRNA‐, vector‐, and inactivated virus‐based COVID‐19 vaccines by Hadeel T. Zedan (12535521)

“…We analyzed ADCC activity targeting SARS‐CoV‐2 spike (S) and nucleocapsid (N) proteins in convalescent sera following WT SARS‐CoV‐2‐infection (<i>n</i> = 91), including symptomatic and asymptomatic infections, omicron‐infection (<i>n</i> = 8), COVID‐19 vaccination with messenger RNA‐ (mRNA)‐ (BNT162b2 or mRNA‐1273, <i>n</i> = 77), adenovirus vector‐ (<i>n</i> = 41), and inactivated virus‐ (<i>n</i> = 46) based vaccines, as well as post‐mRNA vaccination BTI caused by omicron (<i>n</i> = 28). …”

Persona Transparency: Analyzing the Impact of Explanations on Perceptions of Data-Driven Personas by Joni Salminen (7434770)

“…<p dir="ltr">Computational techniques are becoming more common in persona development. However, users of personas may question the information in persona profiles because they are unsure of how it was created. …”