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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. …”
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Special issues in breast cancer gene expression profiling in breast cancer
Published 2009“…• Gene expression profiling has been increasingly used to determine new cancer markers. This technology holds major promises for improving the management of patients with breast cancer in which traditional clinicopathologic parameters do not account for all the heterogeneity of this disease and its distinct prognostic groups. …”
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Raising breast cancer awareness
Published 2015“…<p>Breast cancer is one of the most common forms of cancer in the world, but is highly treatable if detected early enough. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…In aged HSA-mUCP1 mice, urinary MG-derived AGEs/FL ratio was decreased ca. 60% whereas there was no change in CML/FL ratio – a marker of oxidative damage. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…In aged HSA-mUCP1 mice, urinary MG-derived AGEs/FL ratio was decreased ca. 60% whereas there was no change in CML/FL ratio – a marker of oxidative damage. …”
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Regression Analysis between the Different Breast Dose Quantities Reported in Digital Mammography and Patient Age, Breast Thickness, and Acquisition Parameters
Published 2022“…Screening mammography is considered the primary imaging modality for the early detection of breast cancer. The radiation dose from mammography increases the patients’ risk of radiation-induced cancer. …”
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P-glycoprotein expression and function are increased in an animal model of amyotrophic lateral sclerosis
Published 2010“…Expression and functionality of P-glycoprotein (ABCB1, P-gp) and Breast Cancer Resistance Protein (ABCG2, BCRP), two major efflux pumps, were studied. …”
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CD146, a novel target of CD44-signaling, suppresses breast tumor cell invasion
Published 2017“…While the exact function of CD146 in breast cancer (BC) is not completely understood, substantial evidence from our work and others support the hypothesis that CD146 is a suppressor of breast tumor progression. …”
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Ultrasound‑triggered herceptin liposomes for breast cancer therapy
Published 2021“…Exposing the liposomes to low-frequency ultrasound (LFUS) triggered drug release which increased with the increase in power density. Trastuzumab conjugation resulted in enhancing the sensitivity of the liposomes to LFUS. …”
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Mammary adipose dysfunction in the dual epidemic of obesity and breast cancer
Published 2025“…<p dir="ltr">Breast cancer (BC) is one of the leading causes of death among women, with obesity being a significant factor. …”
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Breast cancer cells and bone marrow mesenchymal stromal cells
Published 2017“…Objective The role of direct cell–cell interactions mediating selective bone metastasis by breast cancer cells (BCCs) niche is still mostly unknown. …”
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Breast cancer screening in Lebanon: Understanding knowledge, attitudes and barriers
Published 2024“…Background Breast cancer (BC) has been increasing in both prevalence and incidence in Lebanon. …”
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Epigenetic and breast cancer therapy: Promising diagnostic and therapeutic applications
Published 2022“…<p dir="ltr">The global burden of breast cancer (BC) is increasing significantly. This trend is caused by several factors such as late diagnosis, limited treatment options for certain BC subtypes, drug resistance which all lead to poor clinical outcomes. …”
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Beyond genetics: Exploring the role of epigenetic alterations in breast cancer
Published 2024“…<p>Breast cancer remains a major global health challenge. …”
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Evaluation of Estrone Liposomes using Microfluidics for Breast Cancer Therapy
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Breast Density Estimation in Mammograms Using Unsupervised Image Segmentation
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Ultrasound triggered release of Trastuzumab-conjugated immunoliposomes targeting breast cancer
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Immunomodulatory effects of tumor Lactate Dehydrogenase C (LDHC) in breast cancer
Published 2025“…Silencing LDHC in breast cancer cell lines (MDA-MB-468, BT-549, HCC-1954) enhanced early T cell activation and cytolytic activity. …”