apoA2 correlates to gestational age with decreased apolipoproteins A2, C1, C3 and E in gestational diabetes by Manjunath Ramanjaneya (14603468)

“…</p><h3>Conclusions</h3><p dir="ltr">Apoproteins apoA2, apoC1, apoC3 and apoE are decreased in women with GDM and may have a role in inflammation, as apoA2 and C3 correlated with CRP. …”

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit Masania (7164239)

“…From this and previous transcriptomic studies, signaling involved in enhanced removal of MG-modified protein is likely increased HSPB1-directed HUWE1 ubiquitination through eIF2α-mediated, ATF5-induced increased expression of HSPB1. …”

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit, Masania

“…From this and previous transcriptomic studies, signaling involved in enhanced removal of MG-modified protein is likely increased HSPB1-directed HUWE1 ubiquitination through eIF2α-mediated, ATF5-induced increased expression of HSPB1. …”
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Genome-Wide Association Study of Vitamin D Deficiency in the Middle East With a Relevant Characterization of the Novel <i>SDR42E1 </i>Gene by Nagham Nafiz Ahmad Hendi (19938204)

“…Cellular viability also decreased significantly after the knockout of SDR42E1 in the HCT116 cells.…”

Novel Concrete Mix for 3D Concrete Printing with Special Functions by Malek Omar Mohammad (20433575)

“…To address some of the limitations of conventional concrete construction, the proposed research develops a novel concrete material that possesses better thermal insulation properties, which can decrease energy consumption during the building’s operational phase, and is applicable for 3D concrete printing (3DCP), which removes the need for formwork, increases building design flexibility, and can improve the environmental effect. …”

3D Tissue-Engineered Vascular Drug Screening Platforms: Promise and Considerations by Isra Marei (11312895)

“…<p dir="ltr">Despite the efforts devoted to drug discovery and development, the number of new drug approvals have been decreasing. Specifically, cardiovascular developments have been showing amongst the lowest levels of approvals. …”

3D printing of circular materials: Comparative environmental analysis of materials and construction techniques by Shoukat Alim Khan (14778226)

“…<p>The use of 3D printing in construction activities can help to reduce waste, lower energy consumption, and minimize the environmental impact of building projects. …”

eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways by Zvi Cramer (10742876)

“…Here we show that hippuristanol, a compound that impedes eIF4A in a manner distinct from PatA, similarly inhibits the iNOS/NO pathway and cytokine-induced muscle wasting. …”

Magnesium-reinforced PMMA composite scaffolds: Synthesis, characterization, and 3D printing <i>via</i> stereolithography by Ambreen Afridi (22224310)

“…This mixture was then used to 3D-print test coupons and scaffolds via SLA. The impact of Mg incorporation on the scaffold’s structural integrity, thermal degradation, and biological response was assessed through physicochemical and thermal characterization and biocompatibility experiments. …”

3D Concrete Printing Sustainability: A Comparative Life Cycle Assessment of Four Construction Method Scenarios by Malek Mohammad (17150977)

3D FEM Model on the Parameters’ Influence of EPB-TBM on Settlements of Single and Twin Metro Tunnels During Construction by Masoud Forsat (14158980)

Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications by Sumama Nuthana Kalva (17302906)

“…<p>This study presents a comprehensive performance evaluation of 3D-printed PLA/WE43 magnesium alloy composites, offering novel insights into composition–structure–function relationships for bone tissue engineering. …”

Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies by Fawaz E., Alanazi

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Effect of Mg incorporation on the properties of PCL/Mg composites for potential tissue engineering applications by Sumama Nuthana Kalva (19206064)

“…This study investigates the influence of Mg incorporation on the properties of PCL/Mg composites, aiming to evaluate their suitability for 3D-printable (3DP) tissue engineering applications. …”

A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. …”

Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

“…Hematoxylin and eosin staining and Sirius red staining were performed to identify bone formation in vivo. Results. Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”

Underrepresentation of racial and ethnic minorities in cascade testing for hereditary cancer syndromes by Muhammad Danyal Ahsan (14488278)

“…Cascade testing is critical as relatives found to carry a pathogenic gene variant have the opportunity to pursue targeted cancer risk reduction and early detection, decreasing cancer-associated morbidity and mortality. …”

High-sensitive detection and quantitation of thyroid-stimulating hormone (TSH) from capillary/fingerstick and venepuncture whole-blood using fluorescence-based rapid lateral flow i... by Samar, Shurbaji

“…Most of these TSH-LFIAs are designed for qualitative measurements (i.e., if TSH values > 5, or >15 IU/L) and as screening tests for primary hypothyroidism in children and adults. …”
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Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... by Vijay Ganji (8710491)

Pilot testing of a novel Multi Effect Distillation (MED) technology for seawater desalination by Shahzada Aly (17191465)

“…By implementing this invention's design, the heat transfer area has been decreased and accordingly, the capital cost of the evaporator is reduced by 20%. …”